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Levothyroxine User Reviews & Ratings (Page 4)

Brand names: Synthroid, Euthyrox, Tirosint, Levoxyl, Unithroid, Eltroxin, Tirosint-Sol, Thyquidity, Ermeza, Levolet, Levo-T Novothyrox Eutroxsig Evotrox …show all brand names

Levothyroxine has an average rating of 5.1 out of 10 from a total of 867 reviews on Drugs.com. 41% of reviewers reported a positive experience, while 47% reported a negative experience.

Reviews for Levothyroxine

  • BellB...
  • Taken for less than 1 month
  • January 3, 2020

Euthyrox (levothyroxine) for TSH Suppression "I have been on levo since 2007 for TSH suppression after total thyroidectomy, my pharmacy switched to this type of levo replacement & it is an awful prescription. Within 3 days my chest had such tightness I was ER bound"

1 / 10
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  • Jial
  • Taken for 1 to 6 months
  • November 2, 2015

Tirosint (levothyroxine) for Underactive Thyroid "Devastating side effects - I have developed severely crippling joint pain in both knees, debilitating nerve pain in feet after 12 weeks of taking this drug for underactive thyroid. Also experiencing muscle spasms, tremors, depression, suicidal thoughts, restlessness, some chest pains and tingling all over body. If I could have given it a lower rating, I would have."

1 / 10
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  • Ash
  • May 19, 2020

Tirosint (levothyroxine) for Underactive Thyroid "I have been using Tirosint for over 8 months. I feel good and more energetic during my day. I can actually get more work done without having to take a mid day nap. However, I haven’t done blood work to see how the real effects are taking place within, but for the pass two months I starting experiencing terrible joint pains in my wrist, fingers and legs. So I’m starting to wonder base on some of the other comments if this med is cause these pains."

8 / 10
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Frequently asked questions

  • sd21
  • Taken for less than 1 month
  • March 4, 2015

Synthroid (levothyroxine) for Underactive Thyroid "I began taking my Synthroid three weeks ago and I feel great. First I began breaking my 25 mcg pills into quarters and started out taking only a 1/4 pill. I do this in the morning with a glass of water. I am now taking one 25 mcg pill. My sleeping has improved, I have more energy, my skin looks better and my face does not look tired,. I refused to take this drug initially when I was first diagnosed in 2011 because of a bad scare taking the generic brand, so I let my new meds sit for six months before trying this brand. It works wonders for me and being a life-long gym and karate guy, I have more energy to do laps in the pool and do weights too. I have taken iodine and it works ok, but nothing like my Synthroid. Time will tell."

10 / 10
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  • Pebbles
  • Taken for 5 to 10 years
  • October 25, 2019

Synthroid (levothyroxine) for Underactive Thyroid "I do not notice any difference with the medicine, I’m still suffering from depression and I have extreme hair loss and weight gain even if I don’t eat more than 1500 calories a day. High protein, low carbs"

1 / 10
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Are you taking this medicine?

  • KAano
  • Taken for 1 to 6 months
  • September 19, 2019

Tirosint (levothyroxine) for Hypothyroidism, After Thyroid Removal "Thyroid removed in 2014 due to cancer. Have been on every medicine out there. I was happy on Naturethroid until change in 2018 and it quit working. Not happy with NP or Synthroid. Just tried Tirosint 6 weeks ago. Noticed a lot of aches and pains have disappeared. Although this med is absorbed much easier for me and I had to start skipping a day every 5th day on 125. If I didn't - I experienced pains in lower legs and other signs of over treatment. I just got my blood work and TSH was 1.19. So its working very well. Could prob go on 100 but Dr is happy with what I am doing. I had a small amount of hashimoto in my removed thyroid. This med is stronger than levo so be careful when switching. I was on 135 levo before the switch and started on 125 of this med and I could tell it was still too much. I even eat breakfast with mine. It doesn't even bother it. So those with gastro issues try eating with your dose. I'm happy and hope it stays this way for a while. I'm tired of switching meds."

9 / 10
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  • thyroid...
  • Taken for 2 to 5 years
  • February 7, 2024

Tirosint (levothyroxine) for Hypothyroidism, After Thyroid Removal "Tirosint is the lesser of all the evils for me. When my levels are good (below a 2), then I feel wonderful and am functioning well. If they dip, I feel like everything goes haywire. If I'm too suppressed, my period goes crazy. Serious anxiety in the form of obsessive worrying. If my dose is too low, my period just stops, my face puffs up. I can't sleep. Neurological issues. Acne. I do better having my levels checked every 3 months. I skip my dose on lab day and take it immediately afterwards. This has kept me pretty close to the 2 range. I'm a woman, so healthcare professionals disregard me and my symptoms, so I'm just writing this hoping it will help another woman."

7 / 10
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More FAQ

  • LJL
  • Taken for less than 1 month
  • August 8, 2020

Euthyrox (levothyroxine) for Hashimoto's disease "This drug has many side effects that I am experiencing. Labored breathing - hair loss - blurred vision - fatigue - chest pain - heart skipping beats - nausea - insomnia - was taking a little oblong yellow levorthyroxin that worked great - drug store changed companies and this pill is round white."

1 / 10
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  • Anonymous
  • February 27, 2008

Synthroid (levothyroxine) for Underactive Thyroid "If you boil up balsom tea every day for one month you will cut your colestral and your thyroid down to where you dont have to take drugs. Its no quick fix but its a lot better than taking drugs. My wife is going off a lot of drugs and feels a lot better."

1 / 10
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  • Im...
  • Taken for 1 to 6 months
  • August 28, 2015

For Underactive Thyroid "Diagnosed earlier this year with hypothyroidism after symptoms. I had gained over 35 pounds in a year. I went to the doctor and they put me on Levothyroxine (25 mcg) . I have been on it a month and there is a big difference from before I started the medicine. You must wait at least 6 - 8 weeks before your body even starts to see results because it takes time! In the month that I have been taking it I have gone from 184lbs to 170lbs! I have not changed my diet or exercise routine at all. I am eating more than before (I had no urge to eat and only ate once a day) and actually have hunger pains now to eat. I also take mine at night before bed (it upset my stomach if I took it during the day) and I have more energy and not feeling bloated!!!!"

10 / 10
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  • Anonymous
  • March 17, 2020

Synthroid (levothyroxine) for Hashimoto's disease "Synthroid is terrible it fave me an exacerbation of mental health symptoms! Nervous, restless, anxiety, fatigue, constant dark thoughts and depression. My TSH dropped from .50 to .02 and still no symptoms of hyper just the same symptoms of hypo. Weight gain, tired, depression. I thought I was losing my mind! Trying to adjust psyche meds thinking that was the issue didn't work cuz it was the levo causing the problem. It's difficult to separate symptoms of mental health problems from thyroid problems because they can be similar. Got a referral from PCP to see an Endocrinologist. They switched me to Armour. Significant improvement. Levothyroxine stinks! I'd rather take no thyroid medication and suffer the consequences than take Levothyroxine. "

1 / 10
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  • hypot...
  • April 5, 2012

Tirosint (levothyroxine) for Underactive Thyroid "This is the best thyroid medicine I have taken. I took the generic for several years, I was constantly tired and miserable. Finally, I found Tirosint and I have been so much better. I have been on Tirosint for a year now and I am so glad to have it. I have not had any side effects."

8 / 10
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  • crissy...
  • Taken for 1 to 6 months
  • February 28, 2015

Tirosint (levothyroxine) for Underactive Thyroid "i've tried EVERYTHING. armour did not work for me at all. neither did levoxyl. i know people who swear by armour. i've tried generics. the generic made by abbott lab worked really well (tbey also make synthroid). while i felt better on synthroid or abbott's generic, i did not feel NORMAL. much to my surprise, i feel normal on tirosint. i have energy i haven't had for more than 15 years.... i don't know whether my thyroid will stabilize with this -- but i feel the urge to exercise which i've never had on anything else. my brain is clear and my vision is improving. blood levels were always 'normal' on everything else. but that doesn't mean it was getting cell use.... too expensive, but i can't afford to keep feeling crappy or less than.."

10 / 10
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  • noname
  • October 11, 2013

Synthroid (levothyroxine) for Hypothyroidism, After Thyroid Removal "I have been on synthroid for 20 years. My dosage is 100... To the person whose thyroid was removed and dosage is 250... Sounds a bit high. My tsh level was also 2. 54 the last time I went to the doctor and I feel better than I have in a long time. Anytime I feel a little psycho and mean. I know my levels are off."

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  • Loving...
  • Taken for less than 1 month
  • November 23, 2016

Tirosint (levothyroxine) for Hypothyroidism, After Thyroid Removal "I was on levothyroxine for a year after my cancer surgery/thyroid removal. it was the worst year of my life. I was seriously hating life, because I hurt every single day. Muscle aches, swelling, every symptom you can imagine. Weight gain was the worst. I fired my endo and waited two months to see the new one. If I wasn't married, I'd propose to the man. In three weeks my life has changed. I can go to the gym, and not feel like I have been hit by a truck. No muscle aches. I have lost 9 lbs. Brain fog is lifting. I sleep better, and my I don't feel like a 47 year old stuck in a 90 year old body. I will pay ANY amount of money and I will NEVER go back."

10 / 10
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  • Andrea
  • October 10, 2018

Tirosint (levothyroxine) for Underactive Thyroid "I have Graves Disease & took RAI (radioactive iodine (I-31)) to treat the disease which means now I have to top up my thyroid levels. I’ve previously taken Levoxyl, Synthroid & lastly Armour. Always felt miserable with Levoxyl & Synthroid why the last three years I was taking Armour. Within the last year taking Armour I’ve had terrible inflammation/joint pain, anxiety, insomnia, hair loss, dry skin, weight gain and the list goes on. It was coincidental I forgot to take an Armour pill & realized how in one day all my symptoms went away. Next day I took my Armour and they all returned back. It was so bad I couldn’t even bend my knees. I was miserable! I’ve been reading about Tirosint the last few months and my endo was more than accommodating to let me try it. WOW!!! What a difference, I’m not as hungry, losing weight, no anxiety, sleeping through the night and overall just feeling great as I’ve never had thyroid issues. However, I did have some heart palpitation last night. I’m going to get my lab work done today, as I feel the dosage maybe too high."

10 / 10
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  • Anonymous
  • January 18, 2011

Synthroid (levothyroxine) for Hypothyroidism, After Thyroid Removal "I was put on Synthroid after having my thyroid removed due to cancer 6 yrs ago. I think I've been put on every dosage there is. I have not felt the same since. I'm always tired, I wake up wanting to rip someones head off, armpits sweat horribly, cry over nothing, depressed, hair loss, always colder or hotter then people around me, no energy etc. but when I talk to my doctor and explain my issues I'm told that I'm fine. (I beg to differ, needless to say I'm going to see a new doctor next visit). Though I'm sure Synthroid is a wonderful medication, it just doesn't seem to be working for me in my opinion... my doctor seems to think different."

6 / 10
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  • Very...
  • March 30, 2015

Tirosint (levothyroxine) for Underactive Thyroid "My disabled brother was previously prescribed generic levothyroxine and brand name, Synthroid. On both, he was basically in a continual state of lethargy to the point where he would fall asleep on the commode or at the dining table. Never heard of Tirosint until requesting help. This medicine has been incredible. No more lethargy and continuous sleeping during the day. Family members have commented that he is more alert, engaged and seems to be happy. They would be correct!"

10 / 10
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  • Mills...
  • Taken for 10 years or more
  • August 31, 2017

Synthroid (levothyroxine) for Underactive Thyroid "I took synthroid for 10 years, I had severe insomnia so also took sleeping pills everyday, I was depressed to took anti depressants everyday, had high blood pressured so took drugs for that. I couldn't focus at work and just getting up in the morning felt like a chore In 2013, I switched to natural desiccated thyroid drugs (NDT). It felt like waking up from a bad dream. I'm no longer depressed, my sleep hasn't been this good in my entire adult life. It's like night and day, I wish more doctors gave their patients the opportunity to try solutions other then synthroid; because clearly, it doesn't work for everyone."

1 / 10
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  • Jenni...
  • Taken for 5 to 10 years
  • July 3, 2012

Synthroid (levothyroxine) for Hypothyroidism, After Thyroid Removal "After being diagnosed with hyperthyroidism, had radioactive iodine treatment in 2004. Was put on Synthroid because the radioactive iodine caused hypothyroidism. When this first happened, I had my levels checked every 3 months, and Synthroid levels were adjusted accordingly to fit my needs. We moved the panels to every 6 months for testing, and then yearly. At this point we are at 150mcgs and I feel great. It has been a journey but Synthroid works better for me than the generic, which we tried for a short time. It depends on what works for you and your body. Don't be afraid to let your endocrinologist know if something isn't working for you, you know yourself best. Good luck."

8 / 10
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  • No to...
  • Taken for less than 1 month
  • February 14, 2020

For Underactive Thyroid "I have only been taking this drug for seven days after being diagnosed with hypothyroidism. This drug is awful. I honestly would not suggest it to anyone. I feel like I'm pregnant and have menopause at the same time! I'm having hot flashes, sleeping terribly, my emotions are way out of control (got really upset and in tears over something that normally wouldn't make me react that way). I feel bloated, my joints hurt worse than they did before this med, my heart is racing and I've had muscle spasms in my back and chest and legs. I've also gotten severely nauseated for multiple hours every single time I've taken it. It was so bad yesterday that I had to run to the bathroom because I thought I was going to throw up. I also feel very tired, more depressed than usual, and I have intense anxiety that is making me paranoid. Never again will I take this drug! Don't put yourself through it. It's not worth it."

1 / 10
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  • Anonymous
  • August 11, 2019

Tirosint (levothyroxine) for Underactive Thyroid "I have to say I was excited to triosint but after roughly 8-9 weeks I started to notice tingling in my legs and left arm. I also noticed redness on my chest and vision issues. I wouldn’t have thought it was the medication but since I don’t take it one day out of the week usually every Sunday I would start to feel better by end of day once I started to take it again on Mondays my usual schedule usually by 4 hours later I started to get the tingling feeling again. My legs felt week and knees and joints were hurting. I do better on synthroid"

1 / 10
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  • Thyroid...
  • August 10, 2018

Synthroid (levothyroxine) for Hypothyroidism, After Thyroid Removal "It was discover that I had a nodule/goiter on one my thyroids and the other wasn't functioning at all. After all the tests, I was put on Levothyroxine generic. I had all the symptoms named in all the other comments. But to come to find out, I couldn't take the generic. I was switched to synthroid and have been on it for over 30 years. I had to get it adjusted correctly, over the years, finally got it settled. All the symptoms gradually went away and I have been doing great since. This one has done the job for me. The only thing I have to say is that once on this medication, the weight maintenance has been constant with good diet and exercise. I have always separated vitamins and thyroid med, vitamins in the morning and meds at night. It has worked so far and feeling great. I will continue on this medication. To all, do not give up. There is something that will work with your body and it will be like a miracle. This was my miracle."

10 / 10
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  • 50yrO...
  • March 29, 2011

Synthroid (levothyroxine) for Hypothyroidism, After Thyroid Removal "My surgeon took charge of my Synthroid medicines - big mistake - it was not until I saw an endocrinologist that I found the correct dosage and felt better. It took 18 months to find the correct dosage. I now take 0.2mg Mon-Fri and add 0.05mg on the weekends. This works for me. I had many problems before I got the right dose, and my surgeon said they were not from the Synthroid - he was wrong. I had extreme fatigue, sleeping 10 hours per night and 1 hour in the afternoons. I had trouble remembering things, as well as the inability to concentrate. I was off balance and frequently missed steps and curbs while walking. As well as often feeling like I was going to black out or faint - never did. With the correct dose everything is much better."

9 / 10
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  • Anonymous
  • March 5, 2010

Synthroid (levothyroxine) for Hypothyroidism, After Thyroid Removal "I had my thyroid removed almost a year ago and I can agree that while I have not lost any weight using this drug I have not gained any either. I have had horrible mood swings and lost a great deal of my hair. My Doctor refuses to change the dosage because she says "I'm within normal range" whatever that means? I do feel like I'm experiencing memory loss or having problems concentrating."

5 / 10
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139 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.