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Hysingla ER for Pain User Reviews (Page 4)

Hysingla ER has an average rating of 4.1 out of 10 from a total of 90 reviews for the treatment of Pain. 26% of reviewers reported a positive experience, while 57% reported a negative experience.

Reviews for Hysingla ER

  • imbol...
  • Taken for 1 to 6 months
  • April 14, 2017

"update. took hysingla 30 mg for 1 month, with 10/325 norco. Hysingla A.M. gave severe headaches and nausea. I switched to 10pm and now I wake up less stiff, but can't tell diff during day. I still do norco every 4 hours. I had caudel epidural injection today. It was supposed to be my follow up appointment too, but never chance to speak to PA about new hysingla. She mentioned last month if I tolerated it well, she may increase does to 40mg. I've tried to research 80 mg per day total, but cant find answer, I know thats what she'll look at. I'd like to call and ask about getting hysingla corrected to 40 mg for this month instead. I hate to waste money for no improvements again. I won't know if caudel worked for few days yet, all other injections only lasted 1-2 wks. answers??"

3 / 10
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  • Hmpld
  • Taken for 1 to 6 months
  • November 18, 2017

"This medicine is a joke. They want to take you off Percocet and hydrocodone and put you on this medicine which is supposed to be longer acting. But I’d rather take six Percocet 10 mg a day then one of these. They had me on 40 mg for four weeks it didn’t help with my pain whatsoever."

1 / 10
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12 Report
  • GsanG
  • Taken for 1 to 6 months
  • February 1, 2017

"My medical Internist prescribed this medication for me. I've taking it for three months or 2.5 months. I've noticed the medications doesn't work that much and I would have to take Norco 10/300 for breakthrough pain, because I could just stop taking this medication cold turkey , I would have serious withdrawals that could be deadly. So he started me on Norco 10/300 1 every four hours to prevent withdraws. I noticed my weight had started to increase- I was 128lbs 5'4 and noticed my weight has increased to 140lbs and it all butt an thighs....I'm so insecure about my body, I don't feel right. My husband told me it shouldn't matter just as long as he loves and likes my body...I love him so much...but there's me on the inside that yells out"

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13 Report

Frequently asked questions

  • SueSue
  • Taken for less than 1 month
  • April 29, 2023

"My 76-year-old husband was prescribed Hysingla ER last year and ended up in the ER with serotonin syndrome after taking one pill. He was admitted to the ER almost comatose. He was taking other serotonin-loaded medications and NEVER should have been prescribed this. After a week, he was put into a rehab facility. He contracted COVID and died."

1 / 10
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3 Report
  • Pained
  • Taken for less than 1 month
  • December 4, 2017

"I took 10mg, 3x day hydrocodone for a year prior to a new pain doc in a new state requiring I switch to Hysingla ER. I had only had one 10mg hydrocodone for each of the two days prior to beginning the Hysingla so this was not withdrawals. An hour after the 20mg pill, my heart was pounding hard, short of breath, which progressed to severe abdominal pain, nausea, the worst pain of my life (easily 2-3x my very worst days with stage 3 adhesive arachnoiditis, Ehlers-Danlos, and innumerable tarlov cysts on my spinal cord), joint pain, muscle pain and spasms, and I could literally feel my CSF pulsing in my spinal cord. The doc actually made me take a second dose because she thought I was in withdrawal. I vomited the 2nd one and nearly aspirated it"

1 / 10
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11 Report

Are you taking this medicine?

  • Bubba...
  • Taken for 1 to 6 months
  • January 28, 2023

"At first, this was marginally effective, but only at double the prescribed dosage (20mg). It stopped most of the pain for about 16 hours but took several hours to take effect. After being on this for about a month, it's doing almost nothing for the areas that are having chronic pain, and now is causing pain and stiffness in my hands, neck, and back, areas where I wasn't having any pain prior to this. Strange thing is, regular Hydrocodone works pretty well, with none of the same side effects. Likely whatever is different with the formulation to increase the length of effect is what is causing the increased pain and stiffness. Really disappointing as I was hoping this would work."

2 / 10
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  • KenWo...
  • Taken for 2 to 5 years
  • February 9, 2018

"Great for Pain Management. I had 28 Yrs on Opioids after 12 Surgeries. Total disagreement with Florida wanting to regulate it to 3-7 Day Supply when Florida allowed "Pill Mills" to operate for years. Lost kin to Florida looking the other way, now want Lawsuits against Manufacturers? Absurd thinking, China is killing people by Shipping Opioids via USPS, Buyers unaware of the potency of drugs such as Fentenyl, Oxy etc and Florida Rehabs are milking my Tax Dollars with Commercials showing Resort Living Rehabs. Ignorance is Bliss."

9 / 10
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9 Report

More FAQ

  • Diano
  • March 3, 2018

"Dr started me on Hydrocodone 20 and after being on norco 7.5 for almost a year, the hyd 20 is a blessing. I take 1 tablet in the morning and my pain is manageable all day @ 2-3 level. While on norco 7.5 mg I suffered from 7-9 daily! Physical therapy sessions are more productive as well as gym workouts and gardening activities. I haven't experienced any unpleasant side effects."

10 / 10
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8 Report
  • The...
  • November 30, 2017

"I have had chronic pain since 2002. I have Reflex sympathetic dystrophy (RSD) in low back both legs below knee both feet. Long story short I have been on pretty much every pain med there is. Had over 200 nerve blocks. Had nerve endings burned off. PT you name it. Now I have a medicine dosing machine inside my abdomen with a cath that runs directly into my spinal cord. I tried this hyslinga it's worked great. I'm surprised so many people have not had relief from it. But if I didn't have the pump implant I'm pretty sure I would be on the highest dose they make."

7 / 10
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7 Report
  • Anonymous
  • November 4, 2017

"Had great analgesia with OPANA 40mg q 12 hrs.gradually upward over three year period. But not getting any pain relief (bilateral diabetic peripheral neuropathy) from 30 mg ER HYSINGLA FOR LAST TWO WEEKS. DO I NEED TO TITRATE HIGHER QUICKER? "

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6 Report
  • Lily
  • Taken for less than 1 month
  • July 29, 2023

"Hello Everyone, I started to take Hysingla ER last night. This morning my throat was bothering me and it felt like it was closing up. This evening I retook the medication, two hours later I'm breaking out into a rash. Has anyone had this experience happen to them? Does anyone know if this medication is derived from penicillin? By the way, it has done nothing for me pain-wise. They said this would last all day and 4-6 hours later I'm already taking morphine and/or Norco. It's so frustrating."

5 / 10
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1 Report
  • Anonymous
  • Taken for less than 1 month
  • July 15, 2016

"Too many warnings. I want a refund. There is plastic in these pills. They bounce. Wtf? Gave me a nasty flu like headache. Do not waste your money. Don't know why doc wrote this crap. Never again."

1 / 10
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71 Report
  • Spankey...
  • Taken for less than 1 month
  • February 5, 2015

"At my job I needed medication that would last for up to two shifts or more 16 to 20 hours a day .I have been taking Hysingla ER 40 mg tablet, what a big difference. "

10 / 10
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56 Report
  • lordb...
  • Taken for 1 to 6 months
  • August 29, 2015

"Does not cure pain nor does it last anywhere near 24 hours - more like 10. Complete garbage."

2 / 10
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46 Report
  • Cocom
  • July 20, 2015

"I take 120 mg at night but it takes approx 6 hours to start working & is completely worn off approximately 16-18 hours after dose."

5 / 10
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40 Report
  • BooBear
  • November 26, 2015

"I have been on the pain patch, but it gave me such headaches. Been on hysingla for a few months at night I take it. I only sleep 4/5 hours a night. When it works it's amazing."

9 / 10
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31 Report
  • crazy...
  • Taken for 1 to 6 months
  • May 4, 2017

"my hair is falling out by the handful!"

2 / 10
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20 Report
  • Unkno...
  • Taken for 1 to 6 months
  • January 15, 2017

"Irregular inconsistency on pain control . Many break thru pain through out day . Helps with low pain and mild pain but not for break thru severe pain ."

4 / 10
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18 Report
  • Anonymous
  • Taken for 1 to 6 months
  • September 12, 2017

"Does not work for my chronic pain"

2 / 10
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10 Report
  • Help
  • Taken for less than 1 month
  • April 3, 2020

"Just started Singla ER. Along with 10-325 Percocet 3 times a day. Singla not helping at all. No relief."

1 / 10
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7 Report
  • Anonymous
  • Taken for less than 1 month
  • November 20, 2017

"Terrible did nothing for pain, all I did was sleep and feel letharigic. Pain increased dramatically, I am totally miserable."

1 / 10
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8 Report
  • Akeet
  • February 20, 2018

"Has been a big change in pain level. But believe I need a breakthrough pain med also."

9 / 10
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7 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.