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Hysingla ER for Pain User Reviews (Page 2)

Hysingla ER has an average rating of 4.1 out of 10 from a total of 90 reviews for the treatment of Pain. 26% of reviewers reported a positive experience, while 57% reported a negative experience.

Reviews for Hysingla ER

  • Tom...
  • September 28, 2017

"My doc switched me to this due to some issues with morphine sulphate ER 15mg three times a day. He put me on the Hysingla ER at 20mg once a day with the oxy 15mg x2 for breakthru pain. Been on it for two days and am in constant pain at a 6/7 level. With the other med I was 4/5 on bad days. So disappointed not too mention the cost is more than double for me. Don't know if the dose is just two low considering how long I've been on pain meds Guess I could ask him to up it to 40mg and see if that works. 20mg isn't hacking it at all. So tired of the government sticking its nose into my health."

4 / 10
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  • satrr
  • December 5, 2016

"I'm having a terrible time with the hysingla. The 40mg was so strong I couldn't function. I've been on 30mg for a week. The headaches, I'm tired all the time, cramping. overall feel like crap. I have nothing for breakout pain but Tylenol. I understand why doctors prescribe this because of abuse, but, I have only taken whats prescribed.. It's bad enough that I'm actually on a forum complaining."

1 / 10
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45 Report
  • Yogi
  • Taken for 1 to 2 years
  • June 8, 2019

"I have CRPS (complex regional pain syndrome), which is one of the worst chronic pain conditions known to man, and I get a lot of relief from this medication. Prior to Hysingla I was prescribed Opana ER until it was taken off the market, and I must say I'm thankful for the change. I like the fact that it works without making me feel "drugged." The only downside is constipation that requires daily doses of laxatives. There aren't many extended release choices, but hopefully more options will become available soon for people that aren't getting relief from Hysingla."

10 / 10
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31 Report

Frequently asked questions

  • KB43
  • Taken for 1 to 6 months
  • October 26, 2016

"Hysingla is truly the best option for chronic pain sufferers. Slight headaches no other side affect. Headache goes away with breakthrough pain relief 800ibprophen. It does not give you that "high" feeling other prescribed opiates do. I disagree with many of these reviews because they all don't like it and want their icy back... there is a reason if you didn't ask but your dr just switched you to a abuse deterrent medicine.. please stop making it more difficult in the insurance process to want to cover this drug there are real pained people who benefit this medicine & have their lives back."

8 / 10
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42 Report
  • BS...
  • Taken for less than 1 month
  • January 15, 2017

"I have been taking hysingla 40 ER approximately 2 weeks. I am experiencing severe headache, nausea, and the pain has not subsided one bit. I have tried taking this medicine different times of day hoping it was just the time frame. I have severe withdraw symptoms and can not function. I'm very close to losing my job. I was not abusing my norco, why am I being punished for drug addicts??!!!"

1 / 10
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Are you taking this medicine?

  • Wasted...
  • Taken for less than 1 month
  • September 29, 2017

"First of all, I’ve been on many different pain medications for several years and I’ll have to say this is the worst drug ever made! Purdue should be legally bound for charging over $500 for 30 pills no matter the strength, and for my situation, I’m taking the 40mg pill that Purdue claims works a whopping 24-hours ! First of all, what I have noticed is that it takes 8 hours upon dosing just to start anything, so let’s subtract 24-8 and that leaves 16hrs. Now, if I told you that this miracle and very expensive drug lasted for 16hrs well I would be telling you it is incorrect so in all practicality, it should be scheduled for every 12 hours instead, twice daily. Don’t waste your time or money on this pathetic pill!"

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  • Earlt...
  • July 29, 2015

"Does absolutely nothing I take the 20MG dose along with 4 alieve a day and 4-6 Tylenol.The Hysingla ER did nothing to help. All it does is make me very sleepy 4-5 hour after i take it threw the rest of the day. I mean so sleepy i wouldn't want to try to drive a car."

1 / 10
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More FAQ

  • Tano
  • Taken for 1 to 2 years
  • June 23, 2018

"My Doctor changed me from being on norco 10/325 to hysinglar ER and they keep lowering my dose. In my opinion the hysinglar doesn't work as well and the pain keeps getting worse. Why are dr cutting medicine doses down on people who are in real pain, just because so many others sell their meds and lie about pain."

1 / 10
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34 Report
  • WildL...
  • Taken for 1 to 6 months
  • April 26, 2015

"Very positive experience for me. Sick of taking Hydrocodone all day and night for chronic pain. Still taking Hydrocodone for breakthrough pain once most days, twice others but that is a big decrease for me. I am not nearly as sluggish and feel generally better."

10 / 10
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  • apple...
  • August 26, 2015

"I started taking Hysingla 40 mg about 10 days ago. It does take the pain away about 80% of the time. I wake up thru the night with only about 3 hours sleep. I also have terrible headaches now. I don't know if any of this is related to my medication as I checked the side effects, but this has only started since then. You would think taking pain medication I wouldn't have headaches. Talking to my pain management Dr next week."

8 / 10
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44 Report
  • brdie
  • April 2, 2016

"I started taking 30mg hysingla ER about 6 months ago for severe joint pain along with 3 Vicodin a day for breakthrough medication. I'm now up to 60mg hysingla ER but the 3 per day of Vicodin is just not cutting it. I'm in severe joint pain with RA and osteoporosis. May be possible Vicodin not strong enough I think Tylenol not strong enough for me. I keep running out of the breakthrough medication by 3-4 days every month. Any suggestions?"

6 / 10
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  • Slayer
  • Taken for less than 1 month
  • August 20, 2016

"Biggest waste of money. Don't believe all the lies put out by drug co. Very unpredictable in its delivery. Pain comes in spurts for me so something that won't do me any good for 5 hours is practically worthless to me. If I have to suffer that long for relief then I might as well not taken anything. I understand that's it's not designed for breakthrough pain but still need more predictability in a pills delivery to judge how to take it. I have very bad stomach issues as well."

3 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • November 4, 2016

"This drug didn't work as well as short-acting hydrocodone in lower doses. I had to take up to 20 mg of Tramadol per day for breakthrough pain on top of the 30 mg of Hysingla. It put me to sleep, made me unable to think clearly or efficiently, and didn't allow me to organize my day or complete my tasks as well as I previously had. I had to take it around 6 PM to avoid breathing issues when I laid down and as a result, by the time I got up in the morning I no longer received any pain relief from it - there is no way it works for 24 hours. I'm now in the process of returning to Norco and while still taking hydrocodone am experiencing withdrawal symptoms from getting off the Hysingla. It is far more dangerous and addictive than it is promoted."

1 / 10
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  • Month...
  • March 7, 2019

"I have tried hysinglar twice with the same results. Absolutely zero pain relief. If anything made me a little worse. Should be removed from market for zero efficacy. Ovoid at all cost and save yourself 30 days of miserable pain."

1 / 10
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27 Report
  • tpain...
  • Taken for less than 1 month
  • February 6, 2016

"My doctor put me on Hysingla ER 20 mg on a few weeks ago. Hysingla is causing major problems for me at night. I am waking up 3-4 times every night due to pain and sleep walking. I believe I need an increase in the dosage or put me back on my original treatment of Percocet 7.5mg QID (4 times a day). I am scared that I might walk out of the house and into the road because of this medication. In the few weeks of being on this medication, I have left the house twice within three weeks. The last time this has happened was nearly 4 years ago."

4 / 10
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  • Pd o
  • Taken for 1 to 6 months
  • December 7, 2017

"All of this is the fault of physicians and pharmaceutical company's. At this point they're getting so much pressure to get people off of opioids that they either don't care or have no choice but to prescribe drugs that don't work. If they don't solve this problem people are going to start buying heroin or something else just to get pain relief"

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30 Report
  • Tinker
  • April 8, 2019

"I have 3 auto immune conditions and a very messed up back was on Percocet 10/325 4x day which was helping but neuro put me on Hysingla 20mg and stopped all my other meds including headache shot said this was a miracle drug for all my needs , all this drug done for me is cause more pain and withdrawals if it works for you that's great but some folks have a higher tolerance for meds so if your one of these people who does have a higher tolerance to meds it's not for you save your money because the cost is high and you figure for the price you pay you'd get some kind of relief."

1 / 10
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25 Report
  • Dmccoy
  • July 30, 2017

"My Doctor switched me to Hysingla 40mg from norcos 10/325 , and I'm in so much pain. I don't want to have to take anything, but I don't have a choice because of chronic pain. But I want to go back to Norcos. they work better!!"

1 / 10
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31 Report
  • LongT...
  • Taken for 6 months to 1 year
  • February 7, 2017

"Everyone complaining about headaches and worse pain need to toughen up and wait two weeks before giving up on Hysingla. The headaches and increased pain I think are from Norco "withdrawal". Your brain just needs a week to adapt to the new dosing. Those complaining about it taking a long time to start working or not being consistent are of course correct. No XR meds are perfect but they prevent turmoil caused by peaks and valleys of IR meds...and that is worth it long-term. Give Hysingla a chance. The worst thing about my experience is that during titration the doctors are following guidelines to "round down" from their Norco dose. That's backwards, the does should be higher with any XR."

8 / 10
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32 Report
  • Square...
  • October 24, 2016

"This medication isn't that effective compared to taking Norco since Norco releases most of its metabolytes within an hour immediately causing pain relief. Switching over to Hysingla has not only cost me way more money per month but also has caused me to have severe withdrawals and pain to due it's very slow time release of the medication. I take 20 mg of Norco at a time tid and I'm on the Hysingla 30mg. So with that being said, my body is used to 20mg of morphine every 6 hours. If I'm on the Hysingla 30, it means I'm only getting approximately 1.25mg an hour. That causes the concentration of my morphine levels to drop rapidly. Bottom line, this medication does not work unless you have minor pain that can wait a while till this medication"

2 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • October 1, 2016

"Hysingla really keeps the pain level from my fibromyalgia in check. I no longer feel I am on a pain scale roller coaster. I stay around a 3-4 most days. Others sometimes a 6 but no longer am I at an 8-20 on the pain scale. I also love that I don't feel dopey or tired from the hysingla version like with norco."

9 / 10
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  • Phili...
  • Taken for 6 months to 1 year
  • July 31, 2019

"Hysingla ER Is just another Lie! This medicine takes for ever to work. Way over priced! And Hysingla messes with your intestines causing your bowel movement to become almost like Clay. The maker will never tell the full adverse affects to your body"

2 / 10
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23 Report
  • Btroo...
  • Taken for 1 to 6 months
  • January 2, 2017

"My doc prescribed me 20mg of hysingla and this has to be the most useless drug I've ever been prescribed. I have extreme spinal stenosis and this pain med not only was hard to get but it was super expensive as well. Like $200! My insurance wouldn't touch this drug! I experienced no pain relief with this drug and I took it for 2 months. I finally put my foot down and told the doc this med just does'nt work and to quit playing around giving me these useless medications and to give me something that works. I'm now on 10mg of percocet and it helps me get through the work day. Heck of a lot better than useless Hysingla."

1 / 10
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30 Report
  • mr302
  • Taken for less than 1 month
  • February 4, 2017

"I have just started this medication 120mg once daily, was on oxycontin er 80mg 2x day, with morphine 30mg 3x day as needed. I have multiple disc herniations/stenosis all three areas of the spine, failed cervical fusion,tendenonites left and right shoulder, knee etc.I have had multiple pain issues since the age of 30, and have had other pain treatments including injections, bilateral rhizodamies,gangliotimies. Granted I have just started this rx after my insurance carrier decided not to pay for oxycontin 80mg bid,. I've gotten pretty good relief so far, since I was truly hesitant after reading these reviews, but so far it is no better or no worse than oxy 80 . Have had no major side effects so I'm pretty satisfied so far."

6 / 10
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  • tonye
  • Taken for 1 to 6 months
  • July 20, 2017

"I have 3 herniated discs, spinal stenosis and osteoarthritis. I suffer from constant pain every day. I've been on norco 10/325 4x a day for 3 years now and never abused my medication. A few months ago my doctor had me to try Hysingla ER 40mg. This medication only last about 17hrs and gave me about 30-40% relief with random breakthrough pain. Plus I felt lethargic the entire day, nauseas, constipated, anxious excessive yawning. After putting up with it for two months I talked with my doctor and he switched me back to the Norco. So disappointed. I had high hopes for this medication since it was one pill every 24hrs. it just dose not work as promised and is expensive."

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28 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.