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Guaifenesin for Fibromyalgia User Reviews

Brand names: Mucinex, Mucinex Maximum Strength, Robafen, Tussin Expectorant, Dristan Chesty Cough Guaiphenesin, Guiatuss, Guaifenex LA, GG 200 NR, Family Meltus Chesty Coughs, Humibid, Mucinex Children's Chest Congestion, Breonesin, Guaiatussin, Mucinex for Kids, Tussin Mucus + Chest Congestion, Benadryl Chesty Forte, G Bid, Ganidin NR, Humibid Pediatric, Organ-1 NR, Guaibid-LA, Aquamist, Amibid LA, Mucobid-LA, Fenex-LA, Fenesin, Rompe Pecho EX, Scot-Tussin Expectorant, Guaifenesin LA, Humavent LA, Guiacough, Glytuss, Altarussin, Anti-Tuss, Diabetic Expectorant, Allfen Jr, Genatuss, Siltuss DAS, Gua-SR, Humigen LA, Altorant, Duratuss G, Robitussin Mucus + Chest Congestion, Diabetic Tuss, Guaifenex G, GG-Cen, Benylin E Calmylin Expectorant Guiadrine G-1200 Siltussin DAS-NA Balminil Expectorant Drituss G Beechams Veno's for Kids Chesty Cough Junior Meltus Colour and Sugar Free Expectorant Help I Have Chest Congestion Xpect Bidex-400 Humibid E Fenesin IR Hill's Balsam Chesty Cough Junior Meltus Chesty Coughs with Catarrh Beechams Veno's Expectorant Lemsip Cough Chesty Dristan Chesty Cough Guaifen NR Buckley's Chest Congestion TabTussin 400 Siltussin DAS Diabetic Tussin Mucus Relief Refenesen Chest Congestion Relief Bronchoril Hytuss Mucaplex Air Power Diabetic Tussin Chest Congestion Giltuss EX Expectorant Giltuss Children's EX Expectorant …show all brand names

Guaifenesin has an average rating of 8.5 out of 10 from a total of 103 reviews for the off-label treatment of Fibromyalgia. 84% of reviewers reported a positive experience, while 9% reported a negative experience.

Guaifenesin rating summary

8.5/10 average rating

103 ratings from 108 user reviews.

Compare all 27 medications used in the treatment of Fibromyalgia.

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Reviews for Guaifenesin

  • Poodle...
  • Taken for 1 to 6 months
  • October 5, 2014

Mucinex (guaifenesin) "Unbelievable is all I can say! I could not have doubted this more, but after suffering night after night with horrendous back pain, I sat up at 3am searching the internet for some herb or vitamin I had dismissed the 100 other times I had sat up on the night in pain. I thought it sounded ridiculous, but no more so than anything else I had tried. I started with 1200mg and have remained on that and I feel better than I have in years. I urge you to try this. It has changed my life!"

9 / 10
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254 Report
  • rober...
  • February 24, 2012

Mucinex (guaifenesin) "Diagnosed with severe fibromyalgia, mayofascial pain, IBS. Went through nerve studies etc and muscle biopsy. Finally told I had severe fibromyalgia. The problem was that it was progressing every month. I became suicidal due to pain levels, couldn't walk 10 meters. It saves lives. I might not have the fibromyalgia type you have but this medicine saved my life and if you think spending $30 to try it is a waste then it means you did not suffer enough. I lost it all, wife, home, job but a simple flu tablet got me back everything and it even took my eczema, IBS I had for years. God bless those who came up with that theory. Theory might be wrong but it does the job."

10 / 10
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281 Report
  • rhymi...
  • Taken for 10 years or more
  • June 6, 2020

"I have been on the Guaifenesin Protocol that reverses Fibromyalgia and the Chronic Fatigue that goes along with it for 13 years. I am 76, and I can accomplish more at this age than I did at 63. My Fibro pain and the feeling that I was exhausted all the time has been gone for years. Two little over the counter pills, taken twelve hours apart, reversed all my symptoms. This does not happen overnight. The paperback book, written by Dr. Paul St. Amand, "What Your Doctor May Not Tell You About Fibromyalgia" explained it all. My doctor approved of the protocol with a wave of his hand. "Give it a try," he said. "It can't hurt you." So I did, and, over time, following the protocol precisely, which meant finding MY correct dose, I improved until I was completely reversed. I now have my life back."

10 / 10
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Frequently asked questions

  • lemon...
  • Taken for 2 to 5 years
  • August 15, 2016

"I have been using guaifenesin as a treatment for the reversal of fibromyalgia symptoms for 4 years. As an RN, I was very skeptical since there aren't any positive studies done for this purpose. I had suffered with fibromyalgia symptoms for 12 years, was nearly bed bound, and was researching electric scooters. After relocating to Hawaii, I met an RN who leads a fibromyalgia support group focusing on utilization of guaifenesin. Having nothing to lose by trying this treatment, and trusting a fellow RN, I began the protocol. 4 years later I'm walking a mile daily, cleaning my own home, engaging in multiple craft activities (ceramics, sewing, painting, and gardening), swimming, and enjoying life again. This has given my life back."

10 / 10
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180 Report
  • Rocky
  • Taken for less than 1 month
  • June 11, 2019

"I had been experiencing whole body pain for two years. My doctors kept trying to put me on different medications - gabapentin, melodocam, naproxen - you name it, I’ve tried it. However all of them gave me unwanted side effects. So I researched and read everything I could find ran out natural ways to manage or reduce pain. I stumbled upon The Guaifenesin protocol for fibromyalgia and was intrigued. However, it seemed so restrictive that I decided it wasn’t for me. But I felt like it wouldn’t hurt to just buy the Mucinex tablets 600mg (2x a day) extended release. Literally, the first day my pain levels went from a 9 to a 5. Currently it’s barely noticeable now. Also, no side effects!!! I’ve been on it for a month. I also take magnesium citrate supplements as well. You have nothing to lose but to try it and see if it works for you."

10 / 10
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120 Report

Are you taking this medicine?

  • Stacie...
  • June 20, 2013

Mucinex (guaifenesin) "I have been in terrible and increasing pain since last September. I have had hip and spinal X-rays and MRIs and they show slight arthritis and little else. I had an injection of cortisone in my left hip and now the doctor is recommending a shot to my spine. The pain is so bad, that lately I've been reduced to tears. I went from surfing in August to hobbling in September and the doctors treat me like I'm this no activity couch potato who deserves to feel horrible because I'm getting old and I need to lose weight. Sure I do, I've gained 30 pounds in the last year because I can barely walk. Well, I tried Guaifenesin this afternoon because and it made me fall asleep, and when I woke up, THE PAIN WAS GONE!"

10 / 10
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207 Report
  • Livin...
  • April 18, 2012

Mucinex (guaifenesin) "I was diagnosed at 20 and put on muscle relaxers and pain killers that did nothing more than immobilize me. I read about the guaifenesin treatment and asked my doctor for a prescription. I started at 1200mg extended release 2x daily. FINALLY I had my life back. When Mucinex took away the generic option, I dropped to 600mg 2x daily, and it still does the trick. 12 years later, I still swear by it. I have occasional set backs, but I always bounce back within a week."

10 / 10
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202 Report

More FAQ

  • Melody
  • July 5, 2014

Mucinex (guaifenesin) "With moderate to severe fibromyalgia for 12 years I lost my career and lived in fear of having a life to avoid a flare-up. I have tried every antidepressant, serotonin uptake inhibitor, pain medicine, anti-inflammatory.... you all know, with major side effects that only contributed to fibromyalgia symptoms. March 2014 I got a cold and used Mucinex for the first time and could not believe the relief. I have prayed for someone to invent a NEW MEDICINE for fibromyalgia that would work and it turned out this OLD MEDICINE has returned my life to me. Thank God for Mucinex!"

10 / 10
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171 Report
  • komwill
  • September 16, 2014

Mucinex (guaifenesin) "I was sick with sinus infection and was taking Mucinex. I thought to myself, I am going to be extra sore since I am home from work and resting more than usual because I was not feeling well. I was shocked when after taking Mucinex for a few days, my pain was gone. No more tender spots. My arms had been really bad lately and when I touched them, they were no longer sore. I had no idea of the connection at the time. I googled Mucinex and was amazed that I found studies that something for a cold could possibly help with fibromyalgia. I stopped taking it and the symptoms came back so I started taking it again. I take 2-3 400mg a day. I call this experience accidentally on purpose. It may not work for everyone as we're all different but its worth trying."

9 / 10
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148 Report
  • wildb...
  • December 20, 2011

Mucinex (guaifenesin) "I posted almost 2 months ago. I've been taking Mucinex since then for the fibromyalgia pain (I am not a creature of habit and have a hard time remembering to take any medication but I don't miss it!) I can sincerely say that it continues to work - progressively better - and I find it hard to believe it myself! Pain in my right shoulder that I've had for over 15 years has quietly disappeared. I no longer sleep with a pillow between my knees, and I have so much less pain bending over, etc. I also don't have to clear my throat constantly in the morning like I did so it works great on mucus too. I really didn't expect the results to continue. If you have pain like me, give it a try. No bad effects. I hope it works for you."

10 / 10
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165 Report
  • gloe
  • September 19, 2014

Mucinex (guaifenesin) "Couldn't believe it could be true but it was. Newly diagnosed with fibromyalgia. I read about Mucinex for fibromyalgia; read that it is a muscle relaxant and enhances the analgesic effect of aspirin and Tylenol; and is enhanced by magnesium. Went out and bought the 800 mg with 2 aspirin and some magnesium citrate, and it worked! The pain just seems to dissolve away. I continue to take 800mg (2, 400mg immediate release tablets) with aspirin and magnesium, three times a day, or 1200 mg twice a day. "

8 / 10
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134 Report
  • AmitP...
  • June 15, 2014

Mucinex (guaifenesin) "I've tried dozens of therapies and medicines. Mucinex does better than them all. Since taking it, my pain levels have gone down by 90%. Mucinex doesn't work for everyone. But it's cheap and over the counter. What's the harm in trying? I wish a doctor or website had suggested I try it - would have saved me years of pain."

10 / 10
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133 Report
  • St Ge...
  • August 15, 2016

"I had excessive join pain, gastrointestinal issues, and had severe depression. After a 2 year Guaifenesin program and avoiding 100% of all Salicylates for the past 13 years, I am 100% Free of ALL Fibromyalgia symptoms for over 13 years. At any time in the past 13 years, however, if I so much as consume a Mojito, chew mint gum, use mint toothpaste, or use ANY salicylate, my joint pains reappear within 20 minutes. Be sure to ALWAYS check EVERY Product that you consume or use on your scalp or skin. Use Laundry Detergents and dryer sheets with No Dyes and No Perfumes. Generic products with No Dyes and No Perfumes are perfect. Several "Hypoallergenic" eye make-up brands are NOT hypoallergenic any longer and have caused rashes."

6 / 10
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105 Report
  • Anonymous
  • October 9, 2011

Mucinex (guaifenesin) "My neurologist has tried me on several medicines, but I work in the OR that the Cymbalta and Lexapro do make the pain manageable but I think all the side effects are with me. Mentally I felt like I was floating. I have done the amitriptyline, Neurontin, Buspar, Ultram, Flexeril. But when I read Mucinex I thought you are kidding me. The next morning I went and got some Maximum Strength 12 hr relief and also tried the liquid but I prefer the tablets. Try it I promise it works. Sounds crazy but it does."

10 / 10
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147 Report
  • Racqu...
  • November 3, 2016

"I had intense hip pains and muscle tightness for months and started to use Mucinex because of my cold. After taking it, I kept telling my wife that my hip is feeling better and better. I researched for ingredient in Mucinex and found guaifenesin. There were so many FM comments in the blog that I thought I was reading a wrong section. Been taking 600 mg of guaifenesin three times a day and my pains have subsided about 95% in just 2 days! I don't like taking any kind of drugs and will experiment with a lower dosage and what works for me. I actually stopped taking my dosage one day and the hip pain started to present itself again. Back on guaifenesin and pain subsided dramatically!"

10 / 10
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95 Report
  • aarsprn
  • November 29, 2011

Mucinex (guaifenesin) "After suffering unbearably for 15 years from Fibromyalgia (including 6 years on disability for it). My neurologist suggested I read everything by Dr. D'Amato and try Mucinex. We tried 600 mg twice a day for 6 weeks, no response, upped the dose to 800 mg twice a day for 4 weeks, a little better, then 1200 mg twice a day and it was a miracle. I slowly regained a life again. Throughout this time I also exercised about 1/2 hour a day, which also helps."

10 / 10
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137 Report
  • mspuna
  • August 13, 2016

"I have been using guaifenesin to treat my fibromyalgia since 2001, strictly following the book "What Your Doctor May Not Tell You About Fibromyalgia" by Dr. R. Paul St. Amand. Initially it was all by prescription, then there was otc Mucinex which didn't seem to work as well. I have since been on the plain white Guaifenesin 600mg tablets sold under different brand names such as CVS, Walgreens, Walmart, Target manufactured by Perrigo and they have been most effective. I now run a support group in Hawaii and have seen 100's get well by using guaifenesin. Please check into it: www.fibromyalgiahawaii.com Don't let an old flawed study of over 25year ago stop you from looking into it. You only have your life to gain back! We are proof!"

10 / 10
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91 Report
  • JohnSS
  • Taken for less than 1 month
  • December 29, 2014

Mucinex (guaifenesin) "52 currently, Fibromyalgia began about 16 yrs ago.. Last few years have been really tough, and in discussing at deer camp with friends, one of them mentioned Mucinex. Read up, bought the 600 and raised it to 1200's the next week. My pain is at least reduced by 50%! I'm hearing other supplements in conjunction could help even more but for the moment I'm very pleased to have been told about Mucinex!"

8 / 10
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104 Report
  • BJano
  • November 1, 2019

"I have been disabled with Fibromyalgia and Interstitial Cystitis for over 20 years. In May 2019, I caught a bad cold. I took Guiafenesin to help with the congestion. One night, during that time, I woke up and found that all my Fibromyalgia/Interstitial Cystitis pain was gone! The pain reprieve was short lived, but it gave me enough time to search online and find out about Guiafenesin and Fibromyalgia. I read the members reviews, here at drug.com, and saw other people were getting results with Guiafenesin and Fibromyalgia. I have now been on the Guiafenesin protocol for 6 months and both my Fibromyalgia and Interstitial Cystitis symptoms have dramatically improved. The Guiafenesin protocol is not a quick fix though. There is more to the protocol than just taking Guiafenesin. If you have Fibromyalgia and want to give the Guiafenesin protocol a try, get the book "What Your Doctor May Not Tell You About Fibromyalgia," by R. Paul St. Amand, MD, and Claudia Craig Marek."

10 / 10
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60 Report
  • Tootels
  • Taken for 1 to 6 months
  • July 13, 2015

"I'm not sure how long I've had fibromyalgia, but I'm guessing about 10 yrs. The fatigue/widespread pain and depression were so bad I couldn't stand it any longer. I had read about Mucinex online, but I couldn't fathom how this could possibly help me. One day while trying to work, I just couldn't stand it. I couldn't concentrate, much less keep my eyes open and the pain -- I couldn't move anything without the pain. So I walked across the street to the store and picked it up. I was very desperate. I was literally SO shocked by what happened. Within 30 minutes, the pain wasn't severe and for the first time since I can remember I didn't feel that debilitating fatigue. I told everyone that would listen. It's been miracle for me."

9 / 10
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96 Report
  • Ninas...
  • March 20, 2014

Mucinex (guaifenesin) "I also take Mucinex and have since 2003. As I have read the reviews I have not read any mention of having to remove salicylates from all topical products. Been on Guiafenesin for 10 years and has helped me greatly. "

10 / 10
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106 Report
  • ERINK
  • January 26, 2010

Mucinex (guaifenesin) "I have recently been diagnosed with fibromyalgia. Soon after I had a cold and started taking Mucinex to clear out my sinuses. Not only did my sinuses feel good but I noticed that in general I felt amazing. My body just didn't hurt like it had been hurting for the past few months. So I got online and typed in Mucinex... low and behold the first thing that popped up was using mucinex as a treatment for fibromyalgia ... crazy. I had no idea... so for those of you speculating that it may be a placebo effect ..believe me I felt the difference without knowing that others have used it as a therapy.... it works wonders!"

9 / 10
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131 Report
  • smoore
  • April 15, 2008

Mucinex (guaifenesin) "I never thought that an expectorant used to treat coughs could be this effective for Fibromyalgia pain. I am a pre-med student and when I heard about the possibility of Mucinex(Guaifenesin) being able to relieve pain caused by Fibromyalgia I decided to try it. It has worked better than NSAID'S (Ibuprofen, Aleve, Celebrex) for me. 400mg works great (600mg if using the extended release tablets.)"

9 / 10
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143 Report
  • Cecil...
  • Taken for 10 years or more
  • May 14, 2016

"I have had fibromyalgia for most of my life. Even as a child I suffer from severe leg pain. Each time I was given guaifenesen to help ease asthma congestion I always felt better. Today I take magnesium, guaifenesen, and vitamin D1000 x 3 and I finally have my life back. I tried Lyrica which locked up my jaws. Cymbalta and many other antidepressant's to no avail. For those of you that it doesn't help perhaps you need a second opinion on your diagnosis. I have to many friends on these meds that have reclaimed their life for this treatment to NOT be on to something. Perhaps more research is needed, but why would they do that when the medical and big pharma is getting rich shoving Lyrica, Cymbalta down our throat and getting rich."

10 / 10
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83 Report
  • SDCal...
  • Taken for less than 1 month
  • March 2, 2016

"Mucinex (guaifenesin): "With moderate to severe fibromyalgia for 25 years, lost my career & lived in fear of having a life to avoid a flare-up mostly sleeping bedridden 75% of time. I also have polyneuropathy, trigeminal neuralgia, occipital neuralgia, severe cervical DDD, myelopathy, etc.. have tried every antidepressant, SSRI, pain medicine, anti-inflammatory..you all know, with major side effects. Feb 2016 I got a cold on top of allergies used Mucinex daily 800 mg then up to 1600 mg & could not believe the relief even at 800! I have prayed for someone to invent a NEW MEDICINE for fibromyalgia that would work..turned out this OLD MEDICINE has returned a lot of my life to me, helps the pain, brain fog, fatigue& depression too!"

10 / 10
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83 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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