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Enbrel User Reviews & Ratings (Page 5)

Enbrel has an average rating of 7.8 out of 10 from a total of 268 reviews on Drugs.com. 72% of reviewers reported a positive experience, while 14% reported a negative experience.

Reviews for Enbrel

  • RA-Don
  • Taken for 1 to 6 months
  • March 18, 2017

For Rheumatoid Arthritis "Enbrel has done a fantastic job of relieving the inflammation and pain associated with my severe RA. I began Enbrel three weeks after surgery unrelated to RA. Almost overnight the inflammation in my hands and the painful joints disappeared after the first injection. Have not experienced any bad side-effects to date, other than some minor sinus issues. I eat raw local honey each day, two tablespoons morning and evening to help keep me healthy. Am on Methotrexate 10 mg injection once a week, as well as Enbrel 50 mg injection once a week. Tried going off Methotrexate, but was back on it after ten days as apparently Enbrel alone is not quite enough to treat my RA."

10 / 10
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  • PPRS
  • Taken for less than 1 month
  • February 15, 2014

For Psoriatic Arthritis "I'm diagnosed with psoriatic arthritis. Have only scalp issues and joint swellings and pain in legs, knees, ankles, hand and fingers. Got approved for Enbrel and did 2 weeks ago the first shot. All went well other than I got a cough, night sweat and high blood pressure which it controlled. The second shot gave me a small red stain after 3 days of the size of a quarter which grew to the size my hand palm within a day. My cough is like crazy and my throat itchy. Blood pressure high... I went to the doctor who told me I have to get off I'm allergic to it and a next shot could be life threatening. Benadryl did not help, I got 20 mg Prednisone and it's slightly got better with the redness and pain. I will be changed to Humira."

2 / 10
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  • tina
  • Taken for less than 1 month
  • March 19, 2018

For Rheumatoid Arthritis "I was given Enbrel in January and after 3 injections noticed a rash. The rash after a month put me in the hospital. The rash turned into sores on my legs and after 1 month of stopping injections the rash is worsening. I would use this medication with caution. Take notes of side effects daily. For me the rash is an allergic reaction but it still has me in bed and not working. It feels like knives stabbing in my legs. unable to walk. numbness and swelling in my ankles. Something still isn't right. and its been over a month since last injection."

1 / 10
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26 Report

Frequently asked questions

  • Andi...
  • September 19, 2016

For Psoriatic Arthritis "I have been on Enbrel for 15 years and it has been a life changer. I was literally pain free. Until about a year ago, shortly have the injection I started feeling nauseous, thought maybe it was something I ate but I have since tracked it and every single time to give myself an injection I get nauseated and it lasts for about 36 hours. Has something in the formula of Enbrel changed?? I'll take being nauseated any day over the pain."

8 / 10
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  • Age...
  • March 29, 2015

For Rheumatoid Arthritis "I've been on enbrel with other meds then finally with metrotexato since I was about 19 years old. The other meds I took were strong (harsh). So before I start, the absolute first credit in recovery goes to God. Now about the med, Enbrel, It really has helped me out in living a normal life (just add exercise)... Big difference from not being able to get up to being able to run again. Yet lately each time an injection has been made on my upper left arm, it feels odd. I feel as if the fluid is running into my veins going towards my rib cage. One time it felt as if it was going directly to my heart. Later it would feel warm in those areas, but giving it a few minutes later it would feel cool, oddly fresh. I would like to know if others have had similar symptoms."

9 / 10
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Are you taking this medicine?

  • CET
  • December 10, 2015

For Rheumatoid Arthritis "I have been on Enbrel for about 2 1/2 years & have really had no relief. Prior I was on methotrexate & ended up having to see a liver transplant doctor because of an acute drug injury to my liver. I now have to see the transplant doctor every 3 months so I'd rather be on Enbrel than Methotrexate. But honestly I feel the Enbrel is just a waste of my time. I've also tried Cimzia, Celebrex, Vioxx, etc. Yet here I am at 42 unable to lift my grandchild & 2 shoulder surgeries & 2 toe replacements while on Enbrel."

2 / 10
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  • Ivfiu...
  • July 18, 2018

For Ankylosing Spondylitis "Last 3 months of use I developed neuro problems , tremors, urine issues, skin issues and seizures 2 to 48 hrs after injection, began walking with a list (tilted, off balance), became confused, locked myself in a closet for 2 days. Would turn on burners then go back and forth forgetting to get food out of fridge. Family demanded I stop. After enbrel I had 4 weeks of elevated blood pressure 160 over 95 and pulse of 90. My BP for 15 yrs has been 120 to 130 over 70s and pulse in upper 60s. Urine turned dark brown and had a smell so horrid I would retch. My liver prior to stopping Enbrel enlarged further as did my spleen. Enzyme levels skyrocketed and biliburin levels went from .5 prior to out of range 1.7. platelet levels dropped from low 120 ml per to less than 80ml per. Have regained memory but still have tremors have lost 45 lbs in a month with no end in sight. Still have neurological issues and walk funny Enbrel wrecked my body and Amgen is not interested in what happened."

1 / 10
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More FAQ

  • Peyto...
  • Taken for 2 to 5 years
  • August 26, 2019

For Ankylosing Spondylitis "I have been on Enbrel for about 4 years for Ankylosing Spondylitis. At first it worked well with no adverse reactions. About 1 1/2 years ago I began developing stomach issues. Eight months ago those issues were diagnosed as Crohn’s disease. I have researched whether or not Enbrel can cause Crohn’s or colitis and some studies indicate it can. Wish I would have known that going in. My doctor wants me to switch to Cimzia but I honestly feel that long term all of these medications are poison."

1 / 10
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  • Jay
  • Taken for 2 to 5 years
  • July 18, 2012

For Ankylosing Spondylitis "I was diagnosed with ankylosing spondylitis about 2 years ago after experiencing severe stiffness in the neck and shoulders. I could barely turn my neck at all. Within a couple of weeks of taking Enbrel I was fully flexible and back to my rightful age of 27. 2 years on and I even sometimes forget I have this illness. I recently stopped taking it for 2 weeks and I soon found out what wonders it was working! It is incredible."

10 / 10
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  • Anonymous
  • September 7, 2016

For Rheumatoid Arthritis "I am starting my first shot of Enbrel next week. I am scared to death of the side effects. I have been on Prednisone and Leflunomide for about 6 months and it has helped, but I am not getting the full relief he had hoped for, so my doctor decided to try weekly Enbrel shots. Feeback? Good or bad experience on Enbrel?"

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  • shadbro
  • Taken for 1 to 6 months
  • November 14, 2014

For Rheumatoid Arthritis "Have had rheumatoid arthritis for 5 years. Taking methotrexate for the whole time. It quit working as well. Just went on Enbrel 12 weeks ago, now have right arm swelling, pitting edema, trying to figure out what it is. I am 47 and shouldn't have any extremity swelling. Have never had any swelling of arms or legs. It is not DVT had ultrasound to rule that out. Common sense would say Enbrel triggered something. Hope it resolves and isn't anything serious."

8 / 10
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  • Anonymous
  • November 21, 2011

For Rheumatoid Arthritis "I have had rheumatoid arthritis like symptoms for over 2 years with no regular treatment, only occasional prednisone when the symptoms were too severe to bear. After my symptoms seemed like they never went away and I switched doctors, I have just received my 4th dose of Enbrel and immediately felt a difference after the first shot. My coverage does seem to wear off around day 5, but I still feel better than I have felt in 2.5 years. I would recommend this medicine to anyone considering a treatment that won't alter your life's hectic schedule."

9 / 10
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  • Anonymous
  • November 3, 2009

For Rheumatoid Arthritis "Enbrel saved my life. I've had rheumatoid arthritis for 3 1/2 years. I had severe swelling and pain in almost every joint of my body, which coupled with the exhaustion, left me with little life. The Enbrel with the weekly methotrexate makes me feel basically normal, and able to work and live like a normal person. I found the weekly pens to be very easy to use. I moved to a country that doesn't have the pens, so now I'm on a twice weekly normal injection. I'm terrified of needles and cry like a 2 year old if I see one, so my husband gives me the shots and I can barely feel them. I thank the Lord everyday that I am able to have this medicine!"

9 / 10
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  • SGA
  • July 26, 2009

For Rheumatoid Arthritis "I've been on Enbrel for 2 years and went from being bed bound and using a walker to playing on my company's soft ball team. It has motivated me to live and has allowed me to consider having children now. My husband and I are really excited Enbrel has worked well. The only problem is that I continue to get oral ulcers and bruise easily. I am now having cold symptoms. "

10 / 10
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  • Riden...
  • Taken for less than 1 month
  • March 28, 2016

For Rheumatoid Arthritis "I have severe RA and was started on MTX about 6 months ago already maxed out and pain and inflammation was doing major damage. Two years ago I was running a mile several times a week and when the RA hit I could not even open my bedroom door. Recently was started on Embrel. After the first shot I noticed a 25% improvement with pain and stiffness. I did not find the shot painful as some describe, but I had already been self injecting the MTX. No other side affects thus far. Looking forward to my second injection this week and continued improvement."

8 / 10
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  • Jenny...
  • January 17, 2015

For Plaque Psoriasis "I had psoriasis start around the age of 20 and was not living a healthy lifestyle. After less than two years, getting healthy and topical treatments it went away (clobetasol was the best and tanning). About a year ago it came back with a vengeance (26 years old). It was all over - scalp (a lot), chest, stomach, back, legs, arms. I was so depressed, scared to date anyone, and went back to topical treatment which did not work at all. I tried oral methotrexate, steroids shots to my scalp, prednisone (worked briefly), but nothing would take me back to the days of just having a tiny bit on my elbows and scalp. Enbrel worked! My skin is completely clear outside of a little on my scalp but it's the best my scalp has ever been. Thank you Enbrel."

9 / 10
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  • Babs
  • Taken for less than 1 month
  • November 26, 2019

For Rheumatoid Arthritis "DX with RA December 2018. Now taking MTX, Plaquenil, sulfasalazine and last 3 months added Humira. Not OK yet. Will Start Enbrel in 1 week. Very anxious, reading all of your experiences and life changing diagnosis. Please wish me lots of luck. I have faith that I too will become more optimistic regarding my disease. Thank you all."

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  • Anonymous
  • Taken for 5 to 10 years
  • July 10, 2012

For Rheumatoid Arthritis "I have been taking Enbrel for 5 years which is how long I have had rheumatoid arthritis. My original symptoms which were affecting my mobility in the mornings went away in a few weeks. I now go through periods where I do not have any symptoms for months. I have mild stiffness in my feet in the mornings a few days after I experience a period of stress (like working through the night). This medication has changed the course of my life."

10 / 10
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  • Chris...
  • January 29, 2018

For Rheumatoid Arthritis "I was diagnosed with polymyalgia in 2016 at the age of 38. This disease has taking a toll on me especially at night when I sleep. Well one day I could not move my arms legs had pain in my wrist. Then by the next couple days my shoulders and hips started to hurt. I could not comb my hair, open doors. My rhemotolgist dr placed me on 20mg prednisone after a few days I was able to function again. Prednisone doesn't last all day. My dr prescribed embrel last wk. From the second day I was able to move comfortably in bed. I knew it was working. I felt it over night. I'm so grateful. My CED rate was always high at least in the hundreds. Can't wait to see next month's labs. Because I'm feeling better I'm sure the number has gone down. What do you have to lose but the pain. I tried methatrexate and many other pills nothing worked but the steroids. Still feeling the embrel working next shot is tomorrow. So it hasn't worn off. Haven't felt side effects either. That's a plus."

10 / 10
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  • Sharo...
  • February 11, 2014

For Rheumatoid Arthritis "Was on Methotrexate and Mobic with no relief for 5 years. Took Enbrel and had a life again. Began golfing and bowling again. That suddenly stopped about 8 months ago the fatigue is unbearable and now the swelling and pain is back."

8 / 10
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  • Love...
  • July 10, 2009

For Rheumatoid Arthritis "I have been using Enbrel for almost 2 years with great success. Only recently it stopped working for me. The morning stiffness, hand swelling and all the pain that goes with it was back. My Doctor just started me on Remicade and it started working almost immediately. So don't fret if it stops working for you. I did like doing my own injections with Enbrel, with Remicade it's a 2 hour infusion by your Doctor every 2 months."

5 / 10
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  • inpain
  • September 27, 2011

For Psoriatic Arthritis "My first injection of Enbrel caused me more pain and stiffness then I had before I used the medicine. The right side of my body and my hands hurt so much... happens to be the side I injected. NO way is this for me, it made my skin red and so painful, my joints are stiff and I have so much more pain. My scalp is much more itchy. Also gave me chills and made me feel like I had the flu. I wish I could fine something to stop the pain and my joints from getting deformed."

2 / 10
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  • grate...
  • Taken for 2 to 5 years
  • January 16, 2013

For Rheumatoid Arthritis "When I started Enbrel, I had great results. All the staff at Enbrel was and still is a great support team. They have even enrolled me in the sharps container recovery program. The medication itself is amazing. I have had to try other meditation's as my insurance company did not want to pay for it at first but since they were told that I have tried other medications they do pay for it."

10 / 10
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  • junee...
  • October 30, 2010

For Rheumatoid Arthritis "I have been taking enbrel for 11 years. I worked great for me until the last year when it gradually stopped working. I did the self injection 2X week. Over the last year the relief subsided 2 days after the shots and then when I took the next 3-4 days from the last it would take 24 hours for the relief to kick in, sometimes no relief. My doctor said he wants me to take Humira but for some reason (irrational or not) I am terrified of changing medicines. I had no side effects from Enbrel except some minor sinus irritation -not infections. I am worried I won't be so lucky with another medicine. "

9 / 10
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  • The...
  • Taken for less than 1 month
  • August 9, 2015

For Rheumatoid Arthritis "Had RA for 4 yrs after birth of my baby. I spent 2 years on various meds which did nothing for the pain Then put on Humira which worked wonders for nearly 2 years then started getting flare ups again so they put me on Enbrel 1st injection fine 2nd got small injection site reaction 3Rd injection got massive reaction at injection site & laryngitis Dr diagnosed cellulitis but after reading that laryngitis can be a symptom of allergic reaction I'm leaning towards an allergic reaction and am currently waiting a reply from my rheumatology team!"

7 / 10
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28 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.