The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Compare all 29 medications used in the treatment of Fibromyalgia.
Reviews for Cymbalta to treat Fibromyalgia
Review by MaidenDarkness:
Took Cymbalta for close to a year for Fibro symptoms. For the first couple months it seemed to be helping, and then it stopped. I had worsening sleep difficulty, violent mood swings, and a variety of other side effects. Even with all the Fibro symptoms, I feel better off the med than I ever felt on it. It was also expensive.
I found Cymbalta to be a miracle for me. Within a week of taking it most of my aches and pains disappeared and even my massage therapist stated she noticed a big difference. The problem was the side effects of sexual dysfunction and dry mouth. I added Wellbutrin and love that medication as it greatly improved my mood, but still did not help with the sexual dysfunction. I am now on Lamotrigine and Wellbutrin but the pains in my joints worsened unbelievably, intolerable really. I think I will be dropping the Lamotrigine and going back to the Cymbalta, and just put up with the side effects.
During my mid 40's, I began experiencing excruciating neck pain. I had cervical fusion for a ruptured cervical disk. After the surgery, I have had extreme chronic fatigue, bone pain, overall body pain, and paralysis of one vocal cord. I tried numerous pain medications which had absolutely no effect on my pain. Ultimately, the combination of medications that helped were a low dosage of methadone, Prozac, and Provigil (for narcolepsy). Recently my doctor changed by Prozac to Cymbalta. My pain is now almost
gone! (I am still taking methadone, but maybe it will no longer be necessary. (I changed to Nuvigil for extreme daytime sleepiness.) No side effects from Cymbalta except for slight nausea during the first week of use.
10 users found this comment helpful.
I am on Lyrica 150 mg a day, but it started to lose it's effectiveness after about 5 months. I can't afford to see the doctor or get more Lyrica. I tried Cymbalta for my PMDD and hoped that it might help my pain too. My pain was almost completely gone after about 2 days of use! However, I started getting sores on my tongue, emotional numbness, and had zero libido. I stopped using it after about 7 days, and the pain came back worse than ever (I believe I had been overdoing it those few days). I seriously considered putting up with the side effects just to get some pain relief, but I'm trying bupropion XL first.
11 users found this comment helpful.
Review by Mustangfire (taken for less than 1 month):
I recently starting taking Cymbalta for my chronic back (several herniated discs), Costocondritis (chest inflamation), and other related pains classified as Fibromyalgia and Chronic lower back pain. The medication works. It has nearly removed my chest pain and lower back pains by 90% and only a few lingering pains still exist and only in spurts. I've only been on the 60mg dosage for a few weeks, so it may get better. As a side effect, my PE is gone. I never told a doc about it and it has been killing me for a decade. I've tried everything else, none helped. I looked online with a search of Cymbalta and PE and there are sources to confirm it works.
12 users found this comment helpful.
I was on 60mg of Cymbalta for a year or more. Did not want to be on antidepressants all my life so I weaned off it 2 months ago. My fibromyalgia pains have returned with a vengeance, more than before. I am going back to Cymbalta as I want to have some quality of life. I feel debilitated at the moment. Have been taking this tablet in the morning but after reading the reviews on this forum I will change to night.
15 users found this comment helpful.
When Cymbalta became available I was trying it for dysthymia, but found my fibromyalgia and neuropathy became much better. I think it's worth trying, it worked wonders for me and I started taking it with the attitude that it wasn't going to work.
19 users found this comment helpful.
Cymbalta has helped me so much with horrible fibromyalgia pain. It has also helped a great deal with anxiety. However, I no longer believe I can handle the side effects. I have gained over 20 pounds in less than 4 months, despite exercise and calorie restriction. I have severe constipation, very odd dreams, and hot flashes. It is such a shame, because my fibromyalgia is so much better with Cymbalta.
33 users found this comment helpful.
I was on Cymbalta for 2 years and found it to be a wonderful relief of pain and anxiety. The problem I had with it was "brain zaps" and dizziness if I made any sudden movement with my head. I weaned myself off of it slowly and am now back to suffering with pain and anxiety but I do not wish to take Cymbalta again due to the strange brain effect it has. Getting off of it was extremely difficult and luckily I was between jobs or I could not have made it to work during that withdrawal period. Extreme "brain zaps" were the worst thing to get rid of.
23 users found this comment helpful.
I have been on Cymbalta, 60 mg, for over 5 years. It did work for the Fibro pain, even though at stressful times I still felt a minimum of pain. I began to notice after about 3 years that I was very tired all the time and foggy in the brain. It was hard for me to concentrate when someone was talking and words were hard to find when answering them. I finally told my doctor that I wanted to wean off of Cymbalta but I haven't found this to be very easy. Been working on it since June and if I try to lower the dose too fast I become sick like a very bad flu. I am now more clear headed and can talk with clarity since my dose was lowered to around 20 mg.
17 users found this comment helpful.
I am 46 & diagnosed with Fibromyalgia 4 months ago after 1.5 years of unexplained pain, muscle fatigue, exhaustion, etc. The last flare up was so severe I was unable to walk because leg muscles trembling, forearms felt like they were on fire with thousands of needles or bees stinging. I was dropping things. I was very confused and unable to even read an email on my computer. We started with a low dose and am now at 60 mg at bedtime. Along with Tramadol during the day and Flexeril for severe flare ups, as well as moderate exercise, no chocolate, and adequate sleep, I am doing so well. Very few side effects. I am working full time, can wear high heels again & stay awake past 7:00 pm now as well as resuming doing normal household chores.
43 users found this comment helpful.
This medecine delivers as promised as far as pain relief. I noticed a reduction in pain 3 days into taking it. The only pain it doesnt eliminate is my lower back pain. It even helps with my migraines! Negatives are the side effects when getting used to the med (nausea, fatigue) and the fact that your body gets used to it so you have to keep upping the dosage. Recommend starting out on the lowest dosage possible.
19 users found this comment helpful.
Review by Fibromyalgia pain and depression (taken for 1 to 6 months):
I am 46 and have suffered from depression since I was a teenager and fibromyalgia pain and stiffness since I was 30. Nothing else helped much. I tried gabapentin, Prozac, and other anti-depressants. Ibuprofen and tramadol helped a little with the pain but not like Cymbalta! I started on 30mg and worked up to 90mg daily. I feel like I am cured! No more morning pain and stiffness, no more aches and pain and my mood is so much brighter! I haven't felt this happy since I was a kid. I am laughing all the time. I can do things that I haven't been able to do physically for years. I started jogging. Side effects have been a loss of appetite, insomnia, and hot flashes but well worth it!
40 users found this comment helpful.
I have been taking Cymbalta for 3 days. I have had nausea and drop in appetite. I experienced sleeplessness on my 3rd night and hot flashes. I have found that taking it in the morning is better for me. This is my second round of taking Cymbalta.
26 users found this comment helpful.
Review by cymbaltauser (taken for 6 months to 1 year):
I take Cymbalta for both dysthymia and fibromyalgia. I am a female in my mid-40's. Overall, I am at least 70% better than before taking Cymbalta, though not pain-free. I find that I get maximum benefit when I take 120 mg (two 60 mg. capsules at same time) of Cymbalta daily, combined with enough sleep and daily exercise (e.g. at least 20 mins. brisk walking). Also, I need to avoid/minimize physical and psychological stressors (including unpleasant people).
36 users found this comment helpful.
I have been taking Cymbalta for over two years, it worked great in the beginning. I currently take 90mg a day, 60 in the morning and 30 at bedtime. The last few months it does not seem to be working. I have tried several other medications before this one and none of them worked. There are days (most) that I hurt so bad I can't stand to move.
24 users found this comment helpful.
I have taken several depression medicines over the last six years. All with limited results. My entire body started hurting so bad, fatigue, headaches and broken sleep at night. I begged my doctor trying me on Cymbalta because it helped a friend with similar symptoms. My pain was almost gone in a week and completely gone in two. I never realized how bad my pain was until it was gone! I take it at night because I get very sleepy within a few hours. I sleep great and wake up pain free and fully rested. It has helped my depression but not to the extent it has taken away all my pain. I did feel slightly nauseous on and off for a few weeks. My appetite has diminished which has helped me lose 10 pounds.
62 users found this comment helpful.
I have been taking Cymbalta for over 3 years. When I started taking it I was working and it was making me sleepy, so doctor said to take it at night; problem solved. During the years I have had 3 surgeries and I have to stop taking it and I had no side effect or withdrawal symptoms. It helps with my fibromyalgia, mild depression, and pain. My insurance co-pay is $35, but during the donut-hole is is very expensive.
35 users found this comment helpful.
This is my 5th day on 20 mg (lowest dose - 1 pill per day) Cymbalta for fibromyalgia. The first 3 days were tough. My pain would subside during the day, but return almost fully at night. I did not sleep for the first three nights on this medicine. I was also very jittery beginning on day 2. By day 4 most of these side effects subsided and I've been pain free for 48 hours now. I was prescribed 5mg of Ambien to help with the sleep issue. I feel great and energetic for the first time in months. I am thrilled that the lowest dose worked for me.
41 users found this comment helpful.
Review by bigbabe07 (taken for 6 months to 1 year):
I started taking depression medicine when I was 11 years old. I am now 24 and I have been on probably 10 different antidepressants over the years. Nothing has had such a positive effect on me as Cymbalta has. I am truly happy for the first time in a long time. I've been taking Cymbalta for about 8 months now and I feel great. I have also been diagnosed with Fibromyalgia, which is one reason why my doctor thought Cymbalta would be best. Cymbalta has also helped some with my aches and pains. I have very little side effects with this medicine. I get nauseous once in a while and am tired a lot, but it's nothing compared to being without Cymbalta. This is by far the best medicine for depression and fibromyalgia.
42 users found this comment helpful.
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Data sources include Micromedex™ (updated Nov 25th, 2013), Cerner Multum™ (updated Nov 19th, 2013), Wolters Kluwer™ (updated Dec 1st, 2013) and others. To view content sources and attributions, refer to our editorial policy.