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Dexilant for GERD User Reviews

Dexilant has an average rating of 6.2 out of 10 from a total of 154 reviews for the treatment of GERD. 52% of reviewers reported a positive experience, while 33% reported a negative experience.

Dexilant rating summary

6.2/10 average rating

154 ratings from 166 user reviews.

Compare all 121 medications used in the treatment of GERD.

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7%
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3%
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Reviews for Dexilant

  • MrsA
  • October 8, 2013

"After trying Omeprazole (Prilosec), lansoprazole (Prevacid), and other over the counter proton pump inhibitors over the years, I found they were not doing the trick. I had a perpetual sore throat for a few months, and finally went to the ENT who said the acid was burning my esophagus. He put me on Dexilant, which cured that after about 3 weeks. I stayed on it for a few months, the sore throat went away completely and I never had acid problems after that. This is expensive, but worth it! It is the best thing out there, and the trick to taking it is you have to take first thing in the morning, 30 mins before any food on empty stomach. If you have ANY food in your stomach, you will get diarrhea."

9 / 10
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  • Allie
  • January 2, 2021

"Dexilant saved my life. That sounds dramatic but it’s true. I’ve suffered with severe GERD since I was a teenager. I had been on a very high dose of omeprazole for years. I’ve also tried all of the other PPIs. I continued to have “silent reflux” symptoms. For four years, I would get stomach aches and chest pain so bad I would go to the ER and be given opiates. I suspected it was all heartburn but nothing worked to stop the pain. Dexilant was recommended to me once before for my allergy symptoms (possibly worsened by GERD) but I brushed it off because there wasn’t a generic available and I didn’t think it would work better than omeprazole. Let me tell you, it does. It did take a full two weeks to take effect. I haven’t had any pain or GERD symptoms nor any side effects. I don’t know why it’s so effective but I do believe it has to do with the unique formulation and the fact that it only has to be taken once a day at one dose to reduce user error."

10 / 10
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  • patty...
  • September 12, 2013

"I have GERD. Doctors have prescribed medicines that have not been effective. I have tried Nexium, Prevacid, Protonix, Prilosec, with no relief no matter the dosage. When the GERD is not under control I cannot keep anything down. I have thrown up more acid than anyone can imagine. Thanks to my doctor, who prescribed Dexilant the horrors of GERD are behind me. I have suffered no side effects. My advertisement for this medicine would be DEXILANT IS EXCELLENT."

10 / 10
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132 Report

Frequently asked questions

  • Anonymous
  • June 22, 2011

"Dexilant gave me every side effect on the label. "Not Good, I have never had diarrhea like this before. Pain in my stomach, chest pain, like having a heart attack. This has been the worst experience I have ever had. Sure hope others read this before taking this medicine. It should be taken off the market."

8 / 10
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122 Report
  • Natalie
  • Taken for 1 to 6 months
  • May 3, 2019

"Initially diagnosed with Esophagitis (inflammation of the esophagus of acid reflux) 1 month ago. Was on dexilant 60 mg once per day. Had a lump feeling in my throat every day and worse at night while I sleep. Went to see an ENT specialist a few days ago and I was diagnosed with Laryngopharyngeal Reflux Disease(larynx/Pharaynx) acid reflux. Cannot get hold of the specialist who did the initial endoscopy for Esophagitis diagnosis so I informed the receptionist of my experience and was informed he is at the hospital for 2 weeks and I have to wait to see him when he returns to the office. I was told to go to my Family doctor to follow up. FD prescribed taking the dexillant 60 mg twice per day. I am feeling worse since taking dexilant twice per day. I have a choking sensation non stop and at night not sleeping. Awaiting to see the specialist who did endoscopy in a few weeks. Has anybody else had this experience and taking Dexilant 60 mg twice per day?"

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Are you taking this medicine?

  • Anonymous
  • November 13, 2011

"Been taking Dexilant for over a year. Have had diarrhea almost daily and have now began having joint pain and a general tiredness and ill feeling. Works great for reflux but seems to be having an adverse effect on my entire system."

7 / 10
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112 Report
  • Peter...
  • February 12, 2012

"This medication after usuing it for a month plus has ended me up in the emergency room for severe chest pains, dizziness, high blood pressure, occasional, diarrhea, Tightness in the chest , cramps and muscle aches. "

1 / 10
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108 Report
  • Sam...
  • Taken for less than 1 month
  • June 8, 2020

"I developed GERD as a result of taking medications for Parkinson’s disease that irritated my stomach. Once I’d tried a few acid-reducing medicines that failed to work, my doctor prescribed Dexilant. The first time I took it I had horrible stomach pains and several of the ‘rare’ side effects listed by the manufacturer. Most were what I’d call moderate to severe. Nonetheless I took the medicine again, because I’d been told that it can take a few days for the body to adjust to the drug—and indeed on Day 2 the side effects were much milder and I had no acid reflux. Success!—or so I thought. But Day 3 was a nightmare from the beginning. I had lots of pain—stomach, joint, muscle, throat—terrible diarrhea, and more. And to add insult to injury my reflux returned and continued at regular intervals throughout the day and night. I have never had a medicine make me so miserable or scare me so much. Need I say I can’t recommend this drug?"

1 / 10
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  • Anonymous
  • February 15, 2011

"I have had GERD since 1997. I have used Prilosec, Nexium, Aciphex, Prevacid, and Protonix (most recently). NONE of them worked. I was on a double-dose of Protonix when my GP sent me to the GI Specialist for a upper gastrointestina Scope. After that I was prescribed Dexilant. Not only has it 'CURED' my GERD symptoms, it has also settled my IBS symptoms. I used to have to go to the bathroom almost immediately after eating and more than once a day I would have 'emergency' moments where if I didn't get to the bathroom quick I was in trouble. All of those symptoms are gone. I know this doesn't work for everyone but if you're like me and you've tried it all you need to give this medicine a try. It is amazing."

10 / 10
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100 Report
  • Edano
  • Taken for less than 1 month
  • November 22, 2019

"For 6 to seven weeks I started terrible acid reflux. I was 55 years old and always considered I had a steel stomach, could eat anything, the hotter and spicier the better. I broke my foot working and continued to do a roofing job, going up scaffolding with one foot and 60lbs rolls on my shoulder, this is about the time I started getting reflux. It was a suspected hiatal hernia, it may be, still waiting for test results I have tried everything otc. Lost 10lbs in 5-6 weeks because I was scared to eat not knowing what to eat. Finally made it to the doc, and he gave me dexilant 60mg, took it a couple days to kick in and wow....I can eat now..no real side effects as of yet, except some minor stomach aches if I eat to much. I can't stop eating now...ohhhh feels so good. Here I pay $20.92 for a month of dexilant, yeah I'm in Canada...god thanks for our medicare system...just to say...this has worked magically..."

10 / 10
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  • Jules...
  • April 16, 2016

"I somehow contracted h-pylori. This bacteria cause damage to my stomach lining. As a result I began to suffer from serve burning in my stmach & everything I ate gave me heartburn & acid reflux. After seeing a gastro doctor put me on a Dexilant (60mg). It was a life saver. I don't get the burning feeling in my stomach & no refux which was starting to damage my esophagus. My insurance pays a portion of the cost. Then I went to the Dexilant website in which they offer a program for reduced cost. I pay $20 a month for a pill that allows me to eat without suffering. I have had no side effects from this medication. I been taking Dexilant for 6 years everyday. If I miss a day it still works but I can't go longer than 2 days without it."

10 / 10
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66 Report
  • Jan
  • Taken for 5 to 10 years
  • October 13, 2019

"I have been taking Dexilant for about 5 years now and it is definitely helping with my GERD. Before taking Dexilant I tried all the other acid reducing over-the-counter medication and they did not help me. I know Dexilant is expensive but it is worth it so that I start off each day feeling good."

9 / 10
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43 Report
  • Anonymous
  • November 7, 2012

"My Dr. prescribed this after 80mg of Nexium stopped working but after a week of Dexilant, I'm stopping it because of the awful flatulence and abdominal pain starting about 12 hrs after taking it. So glad to get validation here that others have had similar problems since the patient info says this only happens for a small amount of users. "

4 / 10
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81 Report
  • PTF
  • September 30, 2016

"I have been taking Dexilant 60 mg for more than 3 years after taking Nexium for 9 years for GERD. The Nexium quit working so I went on the Dexilant and it saved my life. I started with one every 3 days, then every 2 days and once a day now. I had some anxiety attacks last spring and did not think it had anything to do with this drug. After reading some of the comments it is possible, but has been ok all summer. I am 60 and rode a motorcycle from Seattle to Los Angles in July and traveled Europe in August and Sept. with no acid reflux problems. Just back in Florida after a trip to Vegas and can eat or drink anything. No problems with alcohol, milk or spicy food. Without it I am up all night eating Tums every hour. Good Luck!"

9 / 10
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  • Anonymous
  • May 21, 2011

"I would rate this a 10 for treating GERD; however, I am giving it a 7 due to side effects. I have had no problems with GERD since beginning the medicine but I am experiencing an increase in blood pressure. I also am experiencing dizziness, heart palpitations, shortness of breath, tightness in my throat, pressure in my chest that makes me feel like I am going to vomit (although I do not feel nauseated), and just a general overall bad feeling. This does not happen until the extended release of the medication occurs at about 4-5 hours after administration. Although it treats my GERD symptoms great I have decided it is not worth the other side effects that I am having."

7 / 10
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84 Report
  • Remin...
  • Taken for less than 1 month
  • September 9, 2013

"Dexilant is a God send! I experienced acid reflux out of the blue for the first time that was very severe. For three days straight regardless of the position I was in. My doctor gave me a sample of Dexilant and I felt better within hours, and by the end of the day my reflux subsided. I take 60mg every day, once a day and have been well. I did experience constipation for a few days, but it went away however my stool is not fully normal. The medication is more expensive then other ones on the market, but talk to your doctor and see if he will give you a months worth of samples to see how you feel before you get it prescribed. I eat lots of dairy and spicy foods and all is well."

9 / 10
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72 Report
  • kdbrown
  • Taken for 1 to 6 months
  • May 21, 2013

"Dexilant seems to work better than Prilosec for me, although my symptoms wax and wane. Some days I feel good, other days, I can tell the medicine isn't working well. Not really sure how that is possible since I take it at the same time every day! I do get horrible gas and diarrhea and always end up stopping the meds for a day or two. However, I recently read that Keifer could help with acid reflux, so I started drinking it. It prevents the horrible gas and diarrhea that the Dexilant causes. One glass a day, and I am good! Now I can take the medicine daily as described and hope that it resolves what is causing my GERD. I highly suggest the Keifer for those not tolerating the medicine otherwise."

7 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • May 31, 2016

"I personally had a terrible experience with Dexilant. I have acid reflux and an eroded esophagus, and my GI recommended that I take Dexilant to help lessen my conditions because no other PPIs were working thus far. Dexilant seemed to help my acid reflux, but after a few weeks of being on it, I found myself becoming extremely anxious and depressed. I was crying all the time and having multiple panic attacks every week and sometimes multiple every day. This is the lowest I have ever been, and for months I thought I was going crazy. The moment I realized Dexilant was causing my emotional problems, I got off of it. However, the side effects took several months to dissipate. I would not recommend Dexilant to anyone."

1 / 10
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  • Baze
  • Taken for 1 to 6 months
  • May 24, 2014

"I was taking 60mg same time every day. It seemed to work better at controlling my GERD symptoms after about a month. But around the same time I developed debilitating diarrhea. I continued to take it for another month and the diarrhea didn't go away so I stopped taking it. It's only been a couple of days so far and it still hasn't gotten any better."

1 / 10
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66 Report
  • aimeern
  • May 23, 2010

"10 years had daily heartburn. Tried every prescription and over the counter medicine with minimal relief. Continued to have daily breakthrough heartburn. Ended up eating tums like candy, then took Dexilant, 5 days later realized I hadnt taken any tums and not one episode of heartburn. This is an awesome new medication!"

10 / 10
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82 Report
  • Changed...
  • August 31, 2015

"I have Barrett's as well as severe Gurd! I have tried everything you can think of! I have been on Dexalant for almost 2 weeks and not one episode! I am so happy my doctor gave me this! It has literally changed my life! I have suffered so long with feeling miserable! I had almost lost hope of feeling normal again until I took this! From the first day I took it not one single pain or waking up at night!"

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  • Chris...
  • May 8, 2013

"After reading several of these posts I decided to leave mine. I have severe GERD. My doctor after prescribing several different medicines gave me samples of Dexilant. Ever since then my life has changed for the better. At first I was taking 30mg twice a day then I went to 60mg once daily. Never had I been prescribed more than 60mg total daily. I have read that others were taking way more and more frequently. I think they might want to get a second opinion on dosages. I was on Dexilant for several yrs with NEVER having any side effects. I recently had corrective surgery and hope to never be on meds again for this condition. I would absolutely recommend Dexilant to anyone in need of this kind of medication."

10 / 10
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64 Report
  • Anonymous
  • Taken for 1 to 2 years
  • November 30, 2016

"Nothing worked for me until my doctor gave me samples of Dexilant. I had tried everything over the years. My world changed, the pain went away, and I have no side effects. I know it's very expensive and I have to get authorization from my insurance company, but it's well worth it. I wouldn't be able to function on a daily basis without it."

10 / 10
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  • ria...
  • Taken for less than 1 month
  • March 1, 2017

"I had endoscopy Thanks Goodness its not an ulcer or H.pylori. Since diagnosed with mild gastritis but then doctor gave me Dexilant, domperidone and Gaviscon . Its compulsory to take Dexilant everyday for 2 weeks , but then I had nausea all day, diarrhea 3-4 times a day, my body getting weak and no appetite, its getting worse in the office due to the side effect . After 10 days , I stopped. I could not take it anymore although nurse asking me to continue it. The day after, I could eat without having nausea anymore, I don't even need to go bathroom every time everyday. If you experience same thing like me, STOP it because your body has rejected and caused weak, body aches and cramps, nausea diarrhea. Trust me"

5 / 10
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  • Opie...
  • August 26, 2013

"I had excessive throat clearing after meals for ten years and seems after coffee/tea especially, did not know why? Some days worse than others thought maybe sinus draining or something. Recently I had reflux in my sleep, I had it every night for about 4 weeks straight, terrible stuff! I tried Prilosec OTC for 15 days, and nothing changed, then saw specialist and put on Dexilant. 15 days on Dexilant (1-60mg daily-15 days later I was still having the night reflux-doctor said take two Dexilant a day (morning/night dose). I did, three days later the night reflux gone. It has been a 3 weeks now, no night reflux. Some dry/throat days and light throat/day/burn, not anymore, no throat clearing, no side effects except green stool though."

9 / 10
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59 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.