Dexilant Dosage

Generic name: dexlansoprazole
Dosage form: capsule, delayed release

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Recommended Dose

DEXILANT is available as capsules in 30 mg and 60 mg strengths for adult use. Directions for use in each indication are summarized in Table 1.

*
Controlled studies did not extend beyond 6 months.

Table 1. DEXILANT Dosing Recommendations

Indication

Recommended Dose

Frequency

Healing of EE

60 mg

Once daily for up to 8 weeks

Maintenance of Healed EE and relief of heartburn

30 mg

Once daily*

Symptomatic Non-Erosive GERD

30 mg

Once daily for 4 weeks

Hepatic Impairment

No adjustment for DEXILANT is necessary for patients with mild hepatic impairment (Child-Pugh Class A). Consider a maximum daily dose of 30 mg for patients with moderate hepatic impairment (Child-Pugh Class B). No studies have been conducted in patients with severe hepatic impairment (Child-Pugh Class C) [see Use in Specific Populations (8.7) and Clinical Pharmacology (12.3)].

Important Administration Information

DEXILANT can be taken without regard to food.
DEXILANT should be swallowed whole.
DEXILANT should not be chewed.

For patients who have difficulty swallowing capsules, follow the instructions below for administration:

Administration with Applesauce

1.
Place one tablespoon of applesauce into a clean container.
2.
Open capsule.
3.
Sprinkle intact granules on applesauce.
4.
Swallow applesauce and granules immediately. Do not chew granules. Do not save the applesauce and granules for later use.

Administration with Water in an Oral Syringe

1.
Open the capsule and empty the granules into a clean container with 20 mL of water.
2.
Withdraw the entire mixture into a syringe.
3.
Gently swirl the syringe in order to keep granules from settling.
4.
Administer the mixture immediately into the mouth. Do not save the water and granule mixture for later use.
5.
Refill the syringe with 10 mL of water, swirl gently, and administer.
6.
Refill the syringe again with 10 mL of water, swirl gently, and administer.

Administration with Water via a Nasogastric Tube (≥16 French)

1.
Open the capsule and empty the granules into a clean container with 20 mL of water.
2.
Withdraw the entire mixture into a catheter-tip syringe.
3.
Swirl the syringe gently in order to keep the granules from settling, and immediately inject the mixture through the nasogastric tube into the stomach. Do not save the water and granule mixture for later use.
4.
Refill the syringe with 10 mL of water, swirl gently, and flush the tube.
5.
Refill the syringe again with 10 mL of water, swirl gently, and administer.
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