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Chlorpheniramine / hydrocodone for Cough User Reviews

Brand names: Tussionex Pennkinetic, Hydrocodone GF, HyTan TussiCaps

Chlorpheniramine / hydrocodone has an average rating of 9.4 out of 10 from a total of 105 reviews for the treatment of Cough. 95% of reviewers reported a positive experience, while 3% reported a negative experience.

Chlorpheniramine/hydrocodone rating summary

9.4/10 average rating

105 ratings from 112 user reviews.

Compare all 369 medications used in the treatment of Cough.

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Reviews for Chlorpheniramine / hydrocodone

  • Peter...
  • Taken for less than 1 month
  • July 29, 2020

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "This Tussionex Pennkineticis hands down the best cough medication available. Over the years I've tried many prescription and OTC cough medications, and I've had bad side effects or felt no relief from them. When an ER doctor prescribed me Tussionex, I realized I've found the only medication that does not give me side effects and actually works! This syrup clears up my cough, and helps decrease my post nasal drip and congestion. I am now a presumptive positive for COVID, and my PCP gave me a fill of Tussionex to help with the cough associated with the illness, and it still works great!"

10 / 10
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28 Report
  • SuziQ
  • June 23, 2013

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "I am a 38 year old female who has lupus, asthma, and chronic bronchitis. After 2 months of violent coughing fits at night I was prescribed Tussionex Pennkinetic. The coughing ceased immediately, as did the pain, and I could finally breathe! It did cause itching, strong drowsiness (a plus because I was sleep deprived) and dry mouth, but it was absolutely worth it."

10 / 10
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57 Report
  • Nikki...
  • June 26, 2017

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "Best cough syrup in the world for bronchitis and asthma. I measured and too it as prescribed for 7 days once a day and didn't get high or addicted. Works better than that trash promethazine cough syrup. The government has cracked down so hard on Drs they're scared to help you with what you really need. This cough mixture deserves a 10 or more like a 100! I stopped coughing in 5 minutes and felt better period. No tight chest although on antibiotics. This is what I'd recommend to any suffering like me ."

10 / 10
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38 Report
  • sopra...
  • Taken for less than 1 month
  • September 23, 2016

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "Probably the BEST cough suppressant you can ever be prescribed.i had a cough that was SO SEVERE it kept me up 2 days straight and my throat began to bleed..my dr Rx'd 1 tsp every 12 hours and a z-pack antibiotic. I took the doseage at 6pm and by 7 I was sleeping soundly..I used it to ward off the cough while the antibiotics cured the cough. No point in getting just cough medicine if you don't get the antibiotics to go with it :)"

10 / 10
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37 Report
  • Grace...
  • May 17, 2016

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "Works very well for cough suppression. Much more effective than guaifenesin with codeine. One adult dose at bedtime and I can sleep through the night, 8 hours, and wake up with very minor "hang over" that quickly wears off. Used for deep bronchitis cough, atelectasis after pneumonia, severe flu infection."

10 / 10
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33 Report

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  • TBarr
  • Taken for less than 1 month
  • February 28, 2016

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "This is hands down the best cough medicine I've ever taken. I had a cough so severe that I wet myself or threw up during uncontrollable coughing fits. Needless to say, I couldn't sleep at night for more than the few hours when I just passed out from total exhaustion. My first dose of Tussionex didn't totally get rid of the cough, but it did cut it by about 50%. The second dose helped more. My third dose was last night, and it made it possible for me to get a good night's sleep for the first time in two weeks. I did wake up once with a bad headache, but I can't tell if it's a side effect of the medicine or just part of being sick. Anyway, I'll trade a headache for vomiting from coughing fits any day."

8 / 10
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31 Report
  • grcgm
  • February 13, 2017

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "A doctor once described this medicine to me as the "cough syrup of champions." He wasn't joking. My cough is gone within 10 minutes of drinking this golden liquid miracle. The only reason I didn't give it a full 10 is because of the risk of addiction. It feels amazing- so amazing that you might be tempted to take a little more. Just be careful and take it EXACTLY as prescribed."

9 / 10
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26 Report
  • MDNS
  • November 23, 2015

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "This is the ONLY cough medicine that works for the bronchitis/asthma nightime cough I have, unfortunately, for about 20 years. I just discovered this about 7 years ago maybe. To me, & I have other family members who get this awful cough that OTC meds & other RX cough meds don't even come close to touching.....one dose of this does the trick. We dubed it "liquid gold" not to mention most insurances won't cover it & at anywhere from $80-125 a bottle (big OUCH!) I have bought it in desperation of sleep & feeling better. PLEASE sell the antihistamine part separately!! I don't care about the narc part."

10 / 10
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28 Report
  • Michele...
  • January 30, 2014

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "This cough syrup really works great on quieting my wicked cough (bronchitis).....however, I am one of the few who has a terrible time sleeping when I take it. It also makes me woozy - the equivalent of drinking two glasses of wine. That said, I try to take it at least 6-8 hours before bedtime. The good effects (cough suppressant) is still working, and I get a good night's sleep. I can not drive while taking it. Stay safe!"

8 / 10
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30 Report
  • Grump...
  • Taken for less than 1 month
  • July 7, 2012

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "I was having coughing episodes about 3 hours long. I coughed until I vomited, and even until I lost control of my other bodily functions (both of them). I basically did not sleep more than 3 hours a night (if that) for a week and a half. Since I can expect this cough for another 4 weeks to 4 months, I broke down and gave this a try. It is a testament to the sheer physical force of the pertussis cough that Tussionex only stops it by about 80%. But that 80% makes all the difference! I am sleeping adequately and can keep food down. The unpleasantness that goes along with taking opiates is far, far preferable to this vicious pertussis cough."

8 / 10
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33 Report
  • Teeni...
  • Taken for less than 1 month
  • May 9, 2016

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "This is by far and wide the best treatment for coughing. The worse your cough is, the fewer "high" feelings you will have. I don't mind the hazy feeling all opioids tend to give off, so this is an added benefit for me. The meds help relax your entire body. It can be difficult to sleep on it"

10 / 10
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22 Report
  • Watis...
  • Taken for less than 1 month
  • November 17, 2015

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "This is my go to cough medicine, it absolutely works the best for bronchitis cough or sinus infection. I have experienced headaches with this but found that if I drink a lot of water when I take it, that helps. We call it super syrup in our house."

10 / 10
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22 Report
  • Tiger...
  • April 17, 2016

"My colds always turn into bronchitis. This time it turned into pneumonia. This medicine IS liquid gold. Don't let any doctor tell you otherwise. Some doctors like to prescribe Tussionex Pearls for chronic cough. Don't let them. This is the cough syrup over all cough syrups. After I was released from hospital, I took my first dose and 30 mins later non cough!!"

10 / 10
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20 Report
  • jlapec
  • August 26, 2013

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "This medication will take a cough away but I didn't like the side effects. I normally react great to pain meds but not on this. Couldn't sleep the first night. Woke up with severe headache. Had to take another dose for this cough and still bad headache. Can see this will turn to a migraine. Was so hopeful of this medication."

6 / 10
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24 Report
  • Tacoman
  • August 21, 2018

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "I have had a chronic cough since I was a freshman in high school (I'm now 24). I have been to every specialist tried many many treatments and nobody can figure out what is wrong with me. I've even been to Jacksonvilles mayoclinic specialty cough clinic where they ran extensive tests over a 3 day period; took biopsies of my lungs, esophagus, and trachea, had a CT scan of my chest, did a pH probe test checked for asthma (much more extensive test than the traditional method of detecting asthma) and much more. Nobody can figure out what is wrong with me. I'm at the point where the next treatment option will be Botox injections into my neck to paralyze the nerves in hopes that it helps with the cough reflex. Now, you might be asking yourself, is the above relevant? The answer is yes, and here's why. After reading my extensive summed up cough history, and concluding that nobody has any idea what is wrong with me, the only short term relief I am able to get is from tussionnex."

10 / 10
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15 Report
  • Cool...
  • January 13, 2012

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "I have taken Tussionex for a few years. Before that I was on inhalers, etc. for my allergies and cough. New doctor finally prescribed Tussionex for me. I realize it can be addictive if not used right to the letter. My doctor was reluctant to keep refilling my prescription until I would come in and show him how serious my sinus drainage and cough was. I am so thankful for this medicine. I am 70 yrs old, still working and taking care of a 10 yr old grandson. Without this medicine, I can be just sitting and the clear liquid would drain from my nose. It does not make me drowsy or sleepy at all. Love this medicine and make sure I never abuse my dosage."

10 / 10
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26 Report
  • barbb...
  • November 2, 2009

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "I have been to several internists, three pulmonary docs and still have a chronic cough. Other than perhaps an asthmatic condition so far no specific diagnosis. Nobody could stop the cough. I tried virtually everything until I came to my latest internist who said he could stop the cough and he did. He prescribed Tussionex Pennkinetic. Unlike most of the other comments I don't feel loopy, I feel normal as can be except I can't sleep. So with a bit of an Ambian I sleep, I don't cough much any more and feel great. I take two teaspoons daily each and every day or I am in trouble. I have done this now for about three years and the end results have kept me off Prednisone and able to live a normal healthy active life. Hurray for this medicine!"

10 / 10
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29 Report
  • Luke
  • Taken for 10 years or more
  • August 18, 2019

"Had chronic cough for 15years. Had 5 MD's and a ENT specialist work me up but no reason found. Cough so bad head spins, try to not pass out. Once last winter fell on the wood stove due to a bad cough attack [it just comes on in a second]. Have been on TUSSINEX for years two or three 115ml bottles a year and it REALLY WORKS GREAT. Doctors know it works well but the opioid abuse makes Dr's leary. Fortunately I have a Dr that will prescribe when I need a refill [must have paper script].. You should not have to PLEAD w/ your doctor for a better quality of life..Good luck all.."

10 / 10
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12 Report
  • Shan
  • Taken for less than 1 month
  • July 21, 2020

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "Went to er with breathing issues, tested negative for covid, x-rays, blood work and ECG came back normal but couldn't take a deep breath, and when I did I hurt. Doctor prescribed this liquid gold, 10 minutes after taking it my cough was gone and I could breathe."

10 / 10
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9 Report
  • Baylo...
  • Taken for less than 1 month
  • May 20, 2013

TussiCaps (chlorpheniramine / hydrocodone) "I have had severe hayfever allergies for the past 14 years of my life. This Spring was like every other, I had my regular allergy injection (steriod), and it still didn't kick the symptoms. I was diagnosed with Bronchitis about 3 weeks into allergy season, and prescribed a 10 day dose of this medicine for my cough. Not only did it cure my cough immediately, all of my allergy symptoms have disappeared while taking this. I have never breathed so well in the Spring time!"

10 / 10
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20 Report
  • Waiting...
  • October 16, 2013

"Every fall/winter I get a minor cold that goes away quickly, but the horrible cough lingers and turns into bronchitis. Every fall/winter I beg the doctor for another bottle of this stuff. After trying a dozen other medications, this is the only one that works all the time. It is fabulous."

10 / 10
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19 Report
  • anony...
  • Taken for less than 1 month
  • January 3, 2013

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "This is the nastiest looking and tasting medicine I have ever taken. With that said, the medicine works the best for a cough. I kept myself and my husband awake at night coughing. I took this medicine (only at night) and it worked like a charm. This is the best medicine for a cough (I don't waste my money on Robitussin or Mucinex) and is my go-to medicine whenever I get a pesky cough."

10 / 10
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20 Report
  • Anonymous
  • January 25, 2011

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "Whenever I get a cold I get a wicked cough that actually makes me throw up it is so bad. I took every cough syrup known to man and nothing worked until my dad who is a doctor tried Tussionex. It was incredible I was better in 48 hours! I only get a cold like this every few years but this medicine is the only one that works and doctors are afraid of it because it is a narcotic but if nothing else works why make people suffer?"

10 / 10
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19 Report
  • RAH
  • Taken for 10 years or more
  • December 8, 2021

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "Like others have said, this cough medicine is the only Rx that effectively treats a cough (due to combo of reflux, post nasal drip and allergies…perfect storm) that I have dealt with over the past 30 years!! When this coughing “season” occurs, I cough to the point of vomiting throughout the day and especially at night. I only take this medicine at night when incessantly coughing has kept me awake for several nights. The question is how do you get doctors to prescribe as needed without thinking you are drug seeking or addicted? Other meds just don’t impact the coughing like tussionex…it eradicates the cough!!"

10 / 10
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5 Report
  • Anonymous
  • January 15, 2009

Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "This stuff is a miracle cure for nasty coughs. I was prescribed this for a painful, dry cough that was unresponsive to codeine and OTC cough medicines. It completely killed my cough and allowed me to relax and sleep. If I were a doctor I'd give this stuff out instead of codeine."

10 / 10
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19 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.