Chlorpheniramine / Hydrocodone Dosage

Usual Adult Dose for Cold Symptoms

Chlorpheniramine-hydrocodone 4 mg-5 mg/5 mL oral suspension, extended release:
10 mL orally every 12 hours not to exceed 20 mL daily.

Chlorpheniramine-hydrocodone 8 mg-10 mg/5 mL oral suspension, extended release:
5 mL orally every 12 hours not to exceed 10 mL daily.

Chlorpheniramine-hydrocodone 8 mg-10 mg oral capsule, extended release:
one capsule orally every 12 hours not to exceed 2 capsules in 24 hours.

Usual Adult Dose for Cough

Chlorpheniramine-hydrocodone 4 mg-5 mg/5 mL oral suspension, extended release:
10 mL orally every 12 hours not to exceed 20 mL daily.

Chlorpheniramine-hydrocodone 8 mg-10 mg/5 mL oral suspension, extended release:
5 mL orally every 12 hours not to exceed 10 mL daily.

Chlorpheniramine-hydrocodone 8 mg-10 mg oral capsule, extended release:
one capsule orally every 12 hours not to exceed 2 capsules in 24 hours.

Usual Pediatric Dose for Cold Symptoms

Chlorpheniramine-hydrocodone 4 mg-5 mg/5 mL oral suspension, extended release:
12 yrs or older: 10 mL orally every 12 hours not to exceed 20 mL daily.
6 yrs to 11 yrs: 5 mL orally every 12 hours not to exceed 10 mL daily.

Chlorpheniramine-hydrocodone 8 mg-10 mg/5 mL oral suspension, extended release:
12 yrs or older: 5 mL orally every 12 hours not to exceed 10 mL daily.
6 yrs to 11 yrs: 2.5 mL orally every 12 hours not to exceed 5 mL daily.

Chlorpheniramine-hydrocodone 8 mg-10 mg oral capsule, extended release:
12 yrs or older: one capsule orally every 12 hours not to exceed 2 capsules in 24 hours.

Chlorpheniramine-hydrocodone 4 mg-5 mg oral capsule, extended release:
6 to 11 yrs: one capsule orally every 12 hours not to exceed 2 capsules in 24 hours.

Usual Pediatric Dose for Cough

Chlorpheniramine-hydrocodone 4 mg-5 mg/5 mL oral suspension, extended release:
12 yrs or older: 10 mL orally every 12 hours not to exceed 20 mL daily.
6 yrs to 11 yrs: 5 mL orally every 12 hours not to exceed 10 mL daily.

Chlorpheniramine-hydrocodone 8 mg-10 mg/5 mL oral suspension, extended release:
12 yrs or older: 5 mL orally every 12 hours not to exceed 10 mL daily.
6 yrs to 11 yrs: 2.5 mL orally every 12 hours not to exceed 5 mL daily.

Chlorpheniramine-hydrocodone 8 mg-10 mg oral capsule, extended release:
12 yrs or older: one capsule orally every 12 hours not to exceed 2 capsules in 24 hours.

Chlorpheniramine-hydrocodone 4 mg-5 mg oral capsule, extended release:
6 to 11 yrs: one capsule orally every 12 hours not to exceed 2 capsules in 24 hours.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

The long-acting hydrocodone-containing cough product (marketed as Tussionex Pennkinetic Extended-Release Suspension) is contraindicated for use in patients less than 6 years of age because of their susceptibility to life-threatening and fatal respiratory depression. Prescribers should be familiar with the dosing recommendations of Tussionex before prescribing. In addition, patients and caregivers should use a properly marked measuring device to measure Tussionex to prevent overdose. Overdose of Tussionex in older children, adolescents, and adults has been associated with life-threatening and fatal respiratory depression.

Dialysis

Data not available

See also...