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Chlorpheniramine / Hydrocodone Dosage

Medically reviewed by Drugs.com. Last updated on Jul 31, 2023.

Applies to the following strengths: 4 mg-5 mg; 8 mg-10 mg; 8 mg-10 mg/5 mL; 2 mg-2.5 mg/5 mL; 4 mg-5 mg/5 mL

Usual Adult Dose for Cold Symptoms

Immediate-release (IR): 5 mL orally every 4 to 6 hours as needed
Maximum dose: 20 mL in 24 hours


Extended-release (ER): One dose orally every 12 hours
Maximum dose: 2 doses in 24 hours

Comments:

Use: For the symptomatic relief of cough and upper respiratory symptoms associated with allergy or a cold.

Usual Adult Dose for Cough

Immediate-release (IR): 5 mL orally every 4 to 6 hours as needed
Maximum dose: 20 mL in 24 hours


Extended-release (ER): One dose orally every 12 hours
Maximum dose: 2 doses in 24 hours

Comments:

Use: For the symptomatic relief of cough and upper respiratory symptoms associated with allergy or a cold.

Renal Dose Adjustments

Severe renal impairment: Use with caution

Liver Dose Adjustments

Severe hepatic impairment: Use with caution

Dose Adjustments

Elderly: Use with caution

Precautions

The US FDA requires a Risk Evaluation and Mitigation Strategy (REMS) for all opioids intended for outpatient use. The new FDA Opioid Analgesic REMS is a designed to assist in communicating the serious risks of opioid pain medications to patients and health care professionals. It includes a medication guide and elements to assure safe use. For additional information: www.accessdata.fda.gov/scripts/cder/rems/index.cfm

US BOXED WARNING: RISKS FROM CONCOMITANT USE WITH BENZODIAZEPINES OR OTHER CNS DEPRESSANTS; RISK EVALUATION AND MITIGATION STRATEGY (REMS):


Safety and efficacy of the immediate-release oral solution have not been established in patients younger than 18 years.

The US FDA recommends against use of hydrocodone-containing cough and cold medications in patients less than 18 years because it has been determined that the risks outweigh benefits.

Consult WARNINGS section for additional precautions.

US Controlled Substance: Schedule II (oral suspension/oral solution); Schedule III (oral capsules)

Dialysis

Data not available

Other Comments

Administration advice:


General:

Monitoring:

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.