Chlorpheniramine / hydrocodone Side Effects

Some side effects of chlorpheniramine / hydrocodone may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to chlorpheniramine / hydrocodone: oral capsule extended release, oral liquid, oral suspension extended release

Get emergency medical help if you have any of these signs of an allergic reaction while taking chlorpheniramine / hydrocodone: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• weak or shallow breathing;

• chest tightness;

• painful urination;

• urinating less than usual or not at all; or

• confusion, hallucinations, or unusual behavior.

Less serious side effects of chlorpheniramine / hydrocodone may include:

• dizziness, drowsiness, trouble concentrating;

• mood changes, anxiety;

• blurred vision;

• constipation, nausea, vomiting, loss of appetite;

• dry mouth or throat;

• sweating; or

• mild itching or skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

For Healthcare Professionals

Applies to chlorpheniramine / hydrocodone: oral capsule extended release, oral liquid, oral suspension extended release

Nervous system

Nervous system side effects have included sedation, drowsiness, mental clouding, lethargy, impairment of mental performance, anxiety, fear, dysphoria, euphoria, dizziness, psychic dependence, and mood changes.

Dermatologic

Dermatologic side effects have included rash and pruritus.

Gastrointestinal

Gastrointestinal side effects have included nausea, vomiting, and constipation.

Genitourinary

Genitourinary side effects have included ureteral spasm, spasm of versicle sphincters, and urinary retention.

Respiratory

Respiratory side effects have included respiratory depression, dryness of the pharynx, and occasional tightness of the chest.

The long-acting hydrocodone-containing cough product (marketed as Tussionex Pennkinetic Extended-Release Suspension) may produce dose-related respiratory depression by acting directly on brain stem respiratory centers. Its use of been associated with fatal respiratory depression.

General

General side effects have included impairment of physical performance.

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