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Otezla for Psoriatic Arthritis User Reviews (Page 5)

Otezla has an average rating of 5.0 out of 10 from a total of 122 reviews for the treatment of Psoriatic Arthritis. 30% of reviewers reported a positive experience, while 39% reported a negative experience.

Reviews for Otezla

  • Mattcat
  • Taken for 1 to 6 months
  • September 12, 2017

"On otezla for a short time 4 weeks must come off it because of surgery right shoulder rotator cuff. Up to this point minor side effects but did cause some sleep issues which could also be contributed my upcoming surgery. Had such good results with Biologicals for 15 yrs. until they lost there effectiveness. Now as I get older 67 would like to try something less immunosuppressive. Not encouraged by comments I read. But everyone is different so I will stick it out for four months"

4 / 10
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10 Report
  • Unity
  • June 1, 2017

"8 days in. No relief and as the Enbrel I was taking wears off I am hurting so bad I had to start a course of prednisone. I feel nauseous and depressed. Beautiful weather outside and I don't care. I'm in a farm room watching TV. Miserable and not myself. Called my doctor so we will see what he says to do. I may follow up this post with further results. To be fair it's only Day 8 maybe it will improve"

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9 Report
  • Otezla...
  • Taken for 1 to 6 months
  • March 22, 2021

"My Dr put me on Otezla for my Psoriatic Arthritis and Psoriasis. I have been on it now for a month and a half. Last week, I went to the ER with severe stomach pain. After having a CT, blood work and other tests that came up with nothing to cause this pain, I went home with a script for pain meds. After reviewing 'new' things in my life, I decided that Otezla would have to be the next thing to try. So I contacted my Dr and she agreed to have me go off of it for a week to see what would happen. Every day since then my pain has lessened and lessened. Now, 4 days later, I can breathe without pain, get up by myself, walk semi normally and go almost all day without a pain pill. I can only expect that this will continue until the pain is totally gone - at least I hope that will be the result as there is no other reason for this pain. I hope no one else experiences what I have. I will be dropping Otezla permanently."

5 / 10
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Frequently asked questions

  • Hausf...
  • Taken for less than 1 month
  • February 24, 2018

"When ointments are not as effective as they used to be, I started researching other treatments for Psoriasis. It's a constant battle on my head and wearing black is becoming more difficult. I'm not considering injection therapy so Otezla seemed the perfect solution. Side effects began on day 2 and started to subside after 2 weeks. However, the tension headaches got worse and I stopped treatment after 2 1/2 weeks. I saw little impact on my psoriasis, but I probably didn't take it long enough. However, my Psoriatic Arthritis was completely gone, which of course is acting up again. I so wished this would have worked for me."

5 / 10
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  • Julie
  • Taken for 1 to 6 months
  • June 26, 2022

"Female 54. Scalp psoriasis for 15 years. Psoriatic Arthritis & Osteoarthritis for 15 years. Giant Cell Arteritis 2022. Mild Atherosclerotic Disease main arteries 4 years. Was put on Otezla 6 weeks ago. Had loose bowel movements for 4 weeks, settled now. No real other side effects. I don't drink, I, don't smoke. I'm 3 stone overweight. Stopped eating processed food/fried food/crisp/chocolate/cake/fizzy pop. I feel Otezla is suiting me now, scalp calmed down it used to bleed and was so scaly. Good luck to you all, its not easy is it, just try small changes, to enhance the drugs, not rely in them and carry in bad patterns. Personally I quite like this earth we live on so trying my hardest to stay on it."

9 / 10
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Are you taking this medicine?

  • John...
  • Taken for 1 to 2 years
  • March 31, 2023

"I have been on Otezla for over 2 years and it appeared to be working just fine. Great reduction in swelling and Arthritis pain. Very little itching and skin flairs. Six months ago I started having stomach issues with severe cramping and constant diarrhea after a colonoscopy. Upper GI Diverticula were found and once inflamed caused severe cramping and pain. That problem was solved with antibiotics. Two months more of cramping and an 8 lb weight loss was solved within a day by stopping Otezla. Never again. These are known side effects."

1 / 10
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  • Jbuch...
  • Taken for less than 1 month
  • May 19, 2021

"I started taking Otezla last week I have had severe diarrhea , vomiting , headache and mild dizziness. My Dr.told me to wait til All symptoms disappear then start with one pill and see. I don’t know how I’m going to tolerate this drug"

1 / 10
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More FAQ

  • Bridget
  • Taken for 6 months to 1 year
  • March 25, 2018

"I took this drug for 11 months and finally had to come off it. From Feb to May I did notice an improvement with pain but in June my hands and feet had such nerve pain I could hardly walk and had trouble planting my little garden. I was told the nerve pain could not be from Otezla. From day one I had 2 hours with diarrhea and was told that too would pass. It didn't. I stopped the drug in December before Christmas and the nerve pain and diarrhea completely stopped. Mind you I still have sore feet and hands but feel so comfortable. I had been on Methtrexate and Humira before this drug and they too had massive problems. I have always had Irritable bowel syndrome (IBS) but now my Surgeon said it was undiagnosed diverticulitis that I had kept controlled by diet. These drugs made my bowel much worse and now I need a section removed. How sad is that. Is there even a good drug out there?"

3 / 10
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  • non...
  • Taken for 1 to 6 months
  • October 28, 2021

"After getting psoriatic arthritis, I was told to sign up for otezla with the no copay card by a doctor. So I went online, got the no copay card, started the process to obtain Otezla. The company sent me a 28 day starter pack. And that was it. My next doctor visit the doctor asked how it was going. I explained the 28 day supply I received was great, but I didn't get anymore. The doctor had a nurse call to find out why I only received one month worth. The nurse managed to get another month sent to me after that visit, and again, that was all. When I called the doctor to explain I only received one month, I was told by the nurse that the company said I was noncompliant. The company never told me what I was non compliant for. So I suppose if you get the no copay card, this is the way they treat people."

1 / 10
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  • Anonymous
  • Taken for 1 to 2 years
  • November 30, 2017

"I have been taking Otezla for psoriatic arthritis as well as psoriasis. At first I thought it was a miracle drug helping with the pain and the patches. I did have terrible (and I mean terrible) problems with my stomach. While it improved slightly, after a year and a half it still kills my stomach. I am going to get off of it because it stopped helping with the pain and my skin is worsening. I stuck with it despite the nonstop bowel movements (and headaches) because I thought it was helping, but now that I'm reverting back it isn't worth the nearly debilitating side effects."

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  • GAgirl
  • Taken for less than 1 month
  • October 13, 2018

"My dermatologist put me on Otezla for Granuloma Annulare. Mine is rare in that it is widespread and "recalcitrant." I have been on it for almost 2 weeks now. I have nausea and bathroom urgency throughout the day, though it is lessening as the days go by. I have not yet reached to full dose as I was instructed to take a dose only on a full stomach and I am too nauseous to eat two large meals a day. So I'm up to 30 mg once a day. The headaches have mostly subsided so it gives me hope that I will get acclimated to the other side effects. However I am so uncomfortable and full of aches and pains and exhaustion that I can't tell if I'm depressed or not! I sure don't feel like doing anything at all. So time will tell. I revisit the derm at 5 weeks. So far, I have not noticed any changes in my GA lesions."

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  • syb
  • March 29, 2018

"Though I had no side effects when taking other biologics - or any meds - I had terrible respiratory stuff while on this so went off after a week or so. The way they tested it didn't allow me to know what to expect as they seemed they have data only at a 4 month or so mark. I wouldn't recommend it."

1 / 10
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  • Shane
  • Taken for 1 to 2 years
  • March 30, 2022

"It worked with most side effects in the first month. My hands felt great 30% swelling down. The toughest part of the long term plan is being able to pay for it. At first it is free all is good until the co pay runs out. Next the pharmacy calls to say your prescription is ready but they need an extra 1200$ to refill. Next I check my insurance plan. I picked the highest level plan the most expensive. They say oh no we won’t pay until it hits 4500$. Then after that we will only cover 70% that would leave again 1200$ a month to pay out of pocket. I don’t know anyone who is able too be on this drug for any long term. It’s the old drug dealer scam. Give it to you for free until you get hooked on it. Then start squeezing the money out of you. The company that makes this drug are no better than the street dealers. I had no choice to stop taking it. Too bad they can’t make it affordable for the average person."

5 / 10
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  • Maddie
  • December 22, 2021

"I started this medication about 3 weeks ago. I have psoriatic arthritis. I am having all the side Effects of the medication. I’m going to the bathroom immediately after eating something small. I’m going to try to make it to 8 weeks. It has helped my pain levels, but it hits hard on the stomach. Hopefully it goes away in the weeks to come. I’m allergic to steroids and biologics. I’m coming to a point where every medication doesn’t agree with me. I’m hoping it gets better!"

5 / 10
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  • Speck...
  • Taken for 1 to 6 months
  • September 5, 2022

"I have been taking this medication for 10 weeks now. My psoriasis has progressively gotten worse. I'm about 90% covered. I'm miserable. The nausea, diarrhea, headaches, insomnia, fatigue, muscle cramps, stinging itching pain.... Yeah I need to get off of this medication. I've become agoraphobic, I don't want anyone to see me like this. I'm miserable."

1 / 10
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  • Danrack
  • Taken for less than 1 month
  • December 20, 2021

"I have just started Otezla. It’s a bit rough with diarrhea but I can manage. That said I have been trying to work with Otezla Connect. They are simply awful. I am into call number six with no return calls. Terrible business model."

5 / 10
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  • Batty
  • Taken for 1 to 6 months
  • October 23, 2021

"I'm currently taking Cosentyx and Otezla for the absolute life sucking psoriatic arthritis pain that developed after I had thyroidectomy for cancer and Its my experience that both of these drugs together have helped my pain/skin a lot and neither helped me much on their own “crazy”. For people experiencing upset stomach with Otezla you need to eat a little before taking it and that feeling will go away and the diarrhea will also subside."

8 / 10
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  • Anonymous
  • July 15, 2016

"for my psoriasis keep it under control ,but for my arthritis ,omg it's like having a new life my bones stop hurting and I can walk more than ever. Otezla should be for Arthritis more than psoriasis"

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  • John
  • Taken for 6 months to 1 year
  • October 26, 2015

"I've been taking Otezla for over 6 months now. Works great, joint pain is greatly reduced and the side effects have been very minimal."

10 / 10
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  • Strve...
  • June 15, 2015

"I'm only on day 7 of this medication so too early to tell but I'm am experiencing severe nausea as expected "

5 / 10
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30 Report
  • Otezl...
  • Taken for 6 months to 1 year
  • April 10, 2016

"For me Otezla is a wonder drug. My Psoriatic Arthritis has been non existent for 9 months now since I started taking Otezla."

10 / 10
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25 Report
  • dr ba...
  • Taken for less than 1 month
  • September 19, 2016

"had flu like body aches, constant urge to defecate and brutal migraines from day 3. fatigue was all consuming. rather deal with the joint pain!!"

1 / 10
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23 Report
  • Lola
  • November 7, 2015

"Ortezla made me so very sick. I give this drug all thumbs down. Almost ended up in the hospital. It has very bad side effects, some not even listed"

1 / 10
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25 Report
  • John
  • December 22, 2015

"Works fantastic."

10 / 10
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20 Report
  • Tob
  • November 19, 2019

"30 days in on Otezla. Minimal, if any, side effects, but also no improvement. I will keep updating"

5 / 10
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12 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Psoriatic Arthritis

Symptoms and treatments