Acetaminophen / dichloralphenazone / isometheptene mucate User Reviews & Ratings (Page 3)

• Thomas
• October 1, 2014

Midrin (acetaminophen / dichloralphenazone / isometheptene mucate) for Headache "I've suffered from headaches since elementary school. Somewhat pinpointed it to sinus/allergies about 15 yrs ago since combination of Sudafed and ibuprofen was pretty effective. Take allergy shots, Allegra , Nasonex and still get the headaches unless Sudafed and ibuprofen is taken. My allergist sent me to a neurologist and prescribed Midrin. So far I like it. Took 2 at onset of headache as prescribed and it worked within 45 minutes. Felt a little weird from it. So now I just take one and it works really well all day if not longer. It actually seems to help my eyesight a little and my focus. I was also prescribed a sleep aid but haven't taken any since I really don't have trouble sleeping."

• docday
• Taken for 1 to 6 months
• April 11, 2017

Midrin (acetaminophen / dichloralphenazone / isometheptene mucate) for Headache "For me Midrin is very hit or miss, when I take it at onset of a bad headache, sometimes the headache just in time vanishes before it ever begins, then sometimes its as if I took a placebo, granted the drug has 0 side effects for me. Overall, it's worth having if you have back-up drugs for when it does not work. For those of you that like myself get a terrible trifecta of Migraine, Tension, and Cluster Headaches. You probably know like me that no meds really take the headache away completely once you have one."

• Dede
• Taken for 5 to 10 years
• September 8, 2018

Midrin (acetaminophen / dichloralphenazone / isometheptene mucate) for Headache "Midrin was the best migraine medication! As far as I know I cannot get it anywhere in the area that I live locally in Lake City Florida. I was reading this post to see if anyone had any ideas. I guess I will check on having it compounded at a pharmacy. I have tried Fioricet and fiorinal and they work but my doctor does not like to prescribe them because they have the potential for dependency. She has prescribed for me amerge, it is a triptan and it works but my insurance does not want to pay for it. I do have high blood pressure and sometimes it affects that. Sometimes I use toradol and that works, but it cannot be used regularly."

• LadyC...
• Taken for 10 years or more
• August 16, 2018

Midrin (acetaminophen / dichloralphenazone / isometheptene mucate) for Headache "Midrin is the only medication that I have had success with to combat a migraine. I could take it at the onset of a migraine to stop the pain dead in it's tracks. I'm currently taking Sumatriptan (generic Imitrex) which makes me sleepy enough to sleep through the pain but doesn't always elevate the pain. I've been researching Midrin today to learn whether or not it will ever be available again for migraines but I'm not having much luck. Posting here to see if anyone knows the status and to ask other what meds they used if Imitrex didn't work for them."

• Trian...
• Taken for 1 to 2 years
• March 23, 2015

Midrin (acetaminophen / dichloralphenazone / isometheptene mucate) for Headache "This was the first medication I received for my migraines, and it worked for 90% of my migraines. However, the side effects left me dizzy, disoriented, drowsy, and just generally intoxicated and unable to perform normal work. I switched to Fioricet, and it's been a much better experience since."

• Anonymous
• January 24, 2009

Midrin (acetaminophen / dichloralphenazone / isometheptene mucate) for Headache "I have been taking Midrin for a week for chronic headaches. It does help enough to let me rest. The relief is somewhat short in duration but it is better than anything else I have taken. Considering I have had a chronic headaches for almost 6 weeks - this is progress."

• WhatW...
• Taken for 5 to 10 years
• February 24, 2021

For Headache "I’ve suffered from devastating episodes of migraine and tension headaches for over 30 years. In the early ‘90’s a neurologist at Duke started me on Fioricet which was a great step in the right direction until years later I discovered Midrin — which was like a miracle drug that finally, and for more than a decade, gave me back a normal life. It was a inexcusable for the FDA remove it from the market for non-safety reasons without specifically identifying a superior alternative with the same mechanism of action. Since then, you name it and I’ve tried it...Imitrex, Rizatriptan, Fioricet again, Percocet, Valium, and others. Nothing has every been as clinically effective."

• Midrin...
• Taken for 10 years or more
• September 11, 2020

For Headache "Midrin is far superior for relieving my migraine headaches than any other medication I have tried. Very disappointed it is not currently on the market. I currently take Maxalt, but it is only mildly affective and my migraines tend to rebound much more with an increased duration. Please bring back Midrin!"

• Momof
• Taken for 5 to 10 years
• December 27, 2018

For Headache "I was bedridden for 2 years for my debilitating migraine. I was prescribed Dilaudid by my neurologist. He had no idea how addictive the drug was and when he found out I was sent to rehab to get off of it. The hospital prescribed me the generic for Midrin. It gave me my life back. I'm devastated because this drug is no longer available. I experienced my first pain level 10 and was confined to bed. Being bedridden due to my migraine is not an option. Please put it back on the market."

• chrys
• Taken for less than 1 month
• September 11, 2013

For Headache "I had my pharmacy order this for me because it recently came back on market and I have tried many preventatives and lots of things to stop a migraine, the only thing that worked was a shot of morphine at the hospital. I was on day 2 of a migraine when my medicines came in. I took 2 pills and in 30 minutes I looked around and noticed almost all of my pain was gone, shortly after all pain was gone. I take care of my child every day and I was able to function well with a little cotton mouth and a feeling of taking a narcotic, but it wasn't as bad as a shot of morphine. "

• Ray
• Taken for 10 years or more
• December 23, 2018

For Headache "This medication changed my life for the good. I have taken it as needed for over 25 years without any side effects. Knowing this medication is no longer available has adversely impacted the quality of my thought life. This medication worked every time. No more costly pain filled trips to the ER. No more missed work. Now, my life will never be the same. I am not alone as this medication has been a miracle to others as well. Now my medical bills and lost wages will sky rocket. These other medications are not safe and I won't take them. I just hope that somehow this medication can soon be available again. My life is not the same without it."

• Anonymous
• September 24, 2010

Midrin (acetaminophen / dichloralphenazone / isometheptene mucate) for Headache "I take this for migraines. It is amazing, it usually stops my migraine within a half hour. I usually take 3 Midrin, Excedrin migraine, and 2 aspirin. I take it during aura, usually I have visual disturbances and numbness that travels around my body (along with some other weird crazy stuff). I've also tried Propranolol as a preventative but it causes chest pain and very slow heart rate, so I'm trying Topamax. I still get 3-5 migraines a month, hormone related. I have the Mirena IUD, I would get the Paraguard which has no hormones but I'm allergic to metal, go figure!"

• Nurse...
• July 10, 2013

For Headache "I am so glad that they brought back Midrin, it always worked well for me. My neurologist prescribed me another medication to take its place that contained a barbiturate, so rather than take that I suffered through work because it left me with a foggy feeling. With Midrin I can function with a clear mind and is quicker acting than the medication regime than the Toradol/Zofran combination that my PCP prescribed. I don't notice any side effects with my preventatives either as I did with the other."

• Brittny
• Taken for 1 to 6 months
• December 22, 2017

For Headache "Loved Loved Loved this medication. It knocked my headaches out in 10 minutes and It also reduced the amount of times I got them. I was so sad when my doctor stopped proscribing them to me due to my insurance"

• hope...
• Taken for 5 to 10 years
• September 21, 2022

Midrin (acetaminophen / dichloralphenazone / isometheptene mucate) for Headache "I've had a really great experience with midrin. I spoke with my neurologist and she suggested a compounding pharmacy. I now pick up the generic midrin from the compounding pharmacy and have been since 2017. Check to see if you can do this!"

• bfaiga
• September 16, 2010

Epidrin (acetaminophen / dichloralphenazone / isometheptene mucate) for Headache "While I prefer Migraten (which has caffeine instead of the sedative in Midrin), I LOVE these medicines for headaches. They truly help my painful symptoms. I don't feel "high" or groggy at all, like with narcotics. If you suffer from migraines or tension headaches, try these for sure! (Plus- this was the only relief I got for headaches during pregnancy)."

• Anonymous
• October 26, 2009

Midrin (acetaminophen / dichloralphenazone / isometheptene mucate) for Headache "Five doses at best only eased migraine slightly - and at the cost of increased nausea and increased duration of migraine. Then there's the rebound headaches that last for days. Not worth it for me. Glad it works for others, though. Maxalt works but is terribly expensive and very limited, which means it cannot be used as often as indicated."

• Anonymous
• August 4, 2008

For Headache "Midrin is the absolute best migraine medicine on the market. I have suffered from moderate migraines for years and this is the only medication that I have found to provide fast results. If I take the medicine as I'm supposed to, it will relieve my migraine in about 15 minutes. I would be lost without it."

• LLee
• Taken for 5 to 10 years
• April 16, 2021

For Headache "Midrin is the only medication I have ever found that works for my migraines. Prior to having it prescribed, I tried 9 more modern migraine medications that all failed. I would get migraines that lasted 2-3 days and I would be bedridden and throwing up the entire time. It used to be covered by my insurance with a $20 co-pay for 30 pills; but then it was taken off the market so I had to move to having it formulated. Formulation cost $75 for 30 pills which is pretty darn expensive, but worth it to be able to function normally. But now, I can't believe that I can't even have it formulated anymore. I'm down to 6 pills and I'm quite worried about what I'm going to do in the future."

• Anonymous
• October 15, 2010

Midrin (acetaminophen / dichloralphenazone / isometheptene mucate) for Headache "Been taking Midrin for 6 years, migraines are getting worse with age. Auras, numbness in arms, cluster headaches. Can't take Motrin anymore, doctor says I've taken too much. Midrin makes me feel like I've taken a muscle relaxer after I wake up the next day. So, the day after I take this I feel like a zombie. Still looking for something better!"

• Livin...
• Taken for 10 years or more
• March 10, 2017

For Headache "Midrin, Epidrin, isometheptene-dichloralphenazone-acetaminophen, Isometh/Dich/Apap 65-100-325, whatever variation of name it is dispensed as, it is the best migraine treatment for me. It must be administered early into the headache or it is much less effective. That's the only downside, and one I've managed to deal with successfully over many years now. I take 2 capsules at onset and one more tablet each hour after as needed (usually total of three capsules is enough!) Only side affect is it makes me sleepy. I went through two years trying out various Rx's, shots, treatments with my doctor, but once we tried Midrin I got my life back.The difficulty getting it lately has me jumping through hoops and the price skyrocketed, but it's worth it."

• Loopie
• January 14, 2008

Migquin (acetaminophen / dichloralphenazone / isometheptene mucate) for Headache "My 9 yr old son has suffered from frequent migraines since pre-school. After visiting a pediatric neurologist, he was prescribed Migquin. Although the results were not immediate, my son did experience much relief with this drug combination. Our regular doctor had never heard of this type of medication or ever dealt with migraines in children."

• Anonymous
• Taken for 2 to 5 years
• March 17, 2018

For Headache "I have a history of migraines with aura (my mom has them too), and a few years ago my doctor prescribed me generic Midrin when I was having some of the most excruciating migraines of my life because of hormone fluctuations. I was very sceptical that it would do anything more than ibuprofen or excedrin ever had, but was blown away that it actually reduced 95% my symptoms when they struck! I didn't think anything could actually cover up the pain and nausea and sensitivity. I now keep a bottle of Midrin handy in my medicine cabinet for when I get those debilitating migraines that nothing else will touch. Thankfully I don't get them too often since Medicaid won't cover it and the cost is 180$... :("

• Anonymous
• July 29, 2010

Midrin (acetaminophen / dichloralphenazone / isometheptene mucate) for Headache "Midrin is lovely for my migraines- I was taking 800 mg of ibuprofen a day for them, and now I only have to take one Midrin for a headache to completely go away. There was slight nausea and change of appetite, but that's to be expected."

• Ann
• Taken for less than 1 month
• June 17, 2018

Migrex (acetaminophen / dichloralphenazone / isometheptene mucate) for Headache "I’ve taken one pill a day and it stopped headache in about an hour but headache didn’t return for 24 hours. I was afraid to take migrex because company didn’t require prescription. I think it has different ingredients depending on the country it is from. Also, it contains Tylenol (under the chemical name acetaminophen). I took the drug because I have severe pain almost 3/4 of the month and I had such a horrid headache I wouldn’t have cared if migrex killed me. What a surprise! I have imitrex and am suppose to use sumatriptan stat and migrex long term. Odd company didn’t require prescription??? That makes me nervous."