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Pyridostigmine

Pronunciation

Generic Name: pyridostigmine (peer-id-oh-STIG-meen)
Brand Name: Regonol

Pyridostigmine is used for:

Treating myasthenia gravis. It may also be used for other conditions as determined by your doctor.

Pyridostigmine is a cholinesterase inhibitor. It works by improving nerve impulses in muscles so that the muscles are better able to work.

Do NOT use pyridostigmine if:

  • you are allergic to any ingredient in pyridostigmine
  • you are taking quinine or quinidine
  • you have a stomach, intestinal, or urinary blockage

Contact your doctor or health care provider right away if any of these apply to you.

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Before using pyridostigmine:

Some medical conditions may interact with pyridostigmine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart problems (eg, heart block, slow heartbeat), a urinary tract infection, asthma, or kidney problems

Some MEDICINES MAY INTERACT with pyridostigmine. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Quinine or quinidine because effectiveness of pyridostigmine may be decreased
  • Succinylcholine because actions and side effects may be increased by pyridostigmine

This may not be a complete list of all interactions that may occur. Ask your health care provider if pyridostigmine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use pyridostigmine:

Use pyridostigmine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Pyridostigmine is usually administered as an injection at your doctor's office, hospital, or clinic. If you are using pyridostigmine at home, carefully follow the injection procedures taught to you by your health care provider.
  • If pyridostigmine contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.
  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
  • If you miss a dose of pyridostigmine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use pyridostigmine.

Important safety information:

  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using pyridostigmine.
  • Use pyridostigmine with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking pyridostigmine, discuss with your doctor the benefits and risks of using pyridostigmine during pregnancy. Pyridostigmine is excreted in breast milk. If you are or will be breast-feeding while you are using pyridostigmine, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of pyridostigmine:

All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); diarrhea; fainting; increased production of saliva; increased sweating; muscle weakness; nausea; small pupils; stomach cramps; trouble breathing; vision changes; vomiting; weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include diarrhea; fainting; increased production of saliva; increased sweating; muscle weakness; nausea; small pupils; stomach cramps; trouble breathing; vision changes; vomiting; weakness.

Proper storage of pyridostigmine:

Pyridostigmine is usually handled and stored by a health care provider. If you are using pyridostigmine at home, store pyridostigmine as directed by your pharmacist or health care provider. Keep pyridostigmine out of the reach of children and away from pets.

General information:

  • If you have any questions about pyridostigmine, please talk with your doctor, pharmacist, or other health care provider.
  • Pyridostigmine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take pyridostigmine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about pyridostigmine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to pyridostigmine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using pyridostigmine.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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