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Propranolol concentrate

Pronunciation

Generic Name: propranolol (proe-PRAN-oh-lol)
Brand Name: Generic only. No brands available.

If you have angina or have had heart problems, DO NOT suddenly stop taking propranolol concentrate without first consulting with your doctor. Severe chest pain, heart attack, very fast heart rate, and irregular heart rhythm may occur. If your doctor decides you should no longer take propranolol concentrate, the dosage should be gradually reduced according to your doctor's instructions. You should be closely watched by your doctor and limit physical activity to a minimum, particularly if you have certain kinds of heart disease. Some medicines or medical conditions may interact with propranolol concentrate.


Propranolol concentrate is used for:

Treating high blood pressure; prevention of angina pectoris (chest pain); management of a heart condition called hypertrophic subaortic stenosis; treating and preventing certain abnormal or rapid heart rhythms; improvement of survival after a heart attack in certain patients; treatment of tremor; prevention of migraine headaches; and treating symptoms of adrenal gland tumors. It may be used alone or with other medicines. It may also be used for other conditions as determined by your doctor.

Propranolol concentrate is a beta-adrenergic blocking agent. It works by slowing down the heart and reducing blood pressure, which helps it pump more efficiently and reduces the workload on the heart. It may also interfere with the action of adrenalin and other similar chemicals in the brain preventing migraine headaches.

Do NOT use propranolol concentrate if:

  • you are allergic to any ingredient in propranolol concentrate
  • you have a very slow heartbeat and heart block; had a heart attack and have very low blood pressure or uncontrolled heart failure or shock caused by heart failure
  • you have asthma or Raynaud phenomenon
  • you are a child with diabetes or heart failure
  • you are taking mibefradil

Contact your doctor or health care provider right away if any of these apply to you.

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Before using propranolol concentrate:

Some medical conditions may interact with propranolol concentrate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, plan to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances or are taking medicine for allergies
  • if you have ever had an adrenal gland tumor; anaphylaxis; asthma, chronic bronchitis, chronic obstructive pulmonary disease (COPD), emphysema, or other lung disease; congestive heart failure; narrowing of blood vessels of the legs, arms, stomach, or kidneys; an unusually slow heartbeat; diabetes; kidney problems; low blood sugar; or an overactive thyroid
  • if you have Wolff-Parkinson-White syndrome
  • if you are having surgery

Some MEDICINES MAY INTERACT with propranolol concentrate. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Antiarrhythmics (eg, amiodarone, flecainide, quinidine), antipsychotics (eg, chlorpromazine, haloperidol), bupivacaine, calcium channel blockers (eg, mibefradil, nifedipine, verapamil), cimetidine, ketanserin, mefloquine, or thioamines (eg, tapazole) because potentially life-threatening heart-related side effects may occur, including very slow heart rate; abnormal heartbeat; lightheadedness, especially upon standing; difficulty breathing, especially when lying down; loss of function in the heart and lungs; and swelling of ankles
  • Barbiturates (eg, phenobarbital), clonidine, phenytoin, rifampin, or thyroid hormones (eg, levothyroxine) because they may decrease propranolol concentrate's effectiveness
  • Certain stimulants (adrenalin, pseudoephedrine), hydralazine, insulin, lidocaine, quinazolines (eg, doxazosin), rizatriptan, or theophylline because their actions and side effects may be increased by propranolol concentrate

This may not be a complete list of all interactions that may occur. Ask your health care provider if propranolol concentrate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use propranolol concentrate:

Use propranolol concentrate as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take propranolol concentrate by mouth with or without food, but it should be taken at the same time daily and consistently either on an empty stomach or with food.
  • Use the dropper that comes with propranolol concentrate to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • Do not take antacids containing aluminum within 2 hours of taking propranolol concentrate.
  • Continue to use propranolol concentrate even if you feel well. Do not miss any doses.
  • If you miss a dose of propranolol concentrate, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use propranolol concentrate.

Important safety information:

  • Propranolol concentrate may cause drowsiness, dizziness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use propranolol concentrate with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Propranolol concentrate may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.
  • Propranolol concentrate may mask the signs of hyperthyroidism (overactive thyroid). If you have an overactive thyroid and stop taking propranolol concentrate too suddenly, symptoms of hyperthyroidism (eg, fast heartbeat) may occur.
  • Patients with a history of severe allergic reactions may be more sensitive to allergens while taking propranolol concentrate. These patients may not respond to the usual dose of epinephrine (adrenalin).
  • Diabetes patients - Propranolol concentrate may hide signs of low blood sugar, such as a rapid heartbeat. Be sure to watch for other signs of low blood sugar. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your vision change; give you a headache, chills, or tremors; or make you more hungry. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Tell your doctor or dentist that you take propranolol concentrate before you receive any medical or dental care, emergency care, or surgery.
  • Propranolol concentrate may interfere with certain lab tests, including the glaucoma screening test. Be sure your doctor and lab personnel know you are taking propranolol concentrate.
  • Lab tests, including blood pressure and heart function tests, may be performed while you use propranolol concentrate. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Caution is advised when using propranolol concentrate in CHILDREN; they may be more sensitive to its effects, especially breathing problems and high blood sugar levels.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using propranolol concentrate while you are pregnant. Propranolol concentrate is found in breast milk. If you are or will be breast-feeding while you use propranolol concentrate, check with your doctor. Discuss any possible risks to your baby.

If you suddenly stop taking propranolol concentrate, you may experience WITHDRAWAL symptoms, including worsening chest pain along with possible heart attack.

Possible side effects of propranolol concentrate:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; depression; diarrhea; dizziness; drowsiness; fatigue; hallucinations; lightheadedness; nausea; sleeplessness; stomach cramps; tiredness; vision problems; vivid dreams; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/), or emergency room immediately. Symptoms may include difficulty breathing, especially when lying down; lightheadedness, especially upon standing; pale or blue skin; seizures (convulsions); shortness of breath; swelling of ankles; unconsciousness, possibly leading to lack of heartbeat or breathing; very slow heart rate; wheezing.

Proper storage of propranolol concentrate:

Store propranolol concentrate at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep propranolol concentrate out of the reach of children and away from pets.

General information:

  • If you have any questions about propranolol concentrate, please talk with your doctor, pharmacist, or other health care provider.
  • Propranolol concentrate is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about propranolol concentrate. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: December 3, 2014
Database Edition 14.4.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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