Polyethylene glycol/ electrolytes solution

Generic Name: polyethylene glycol/electrolytes (POL-ee-ETH-i-leen GLYE-kol/e-LECK-troe-lites)
Brand Name: Suclear

Polyethylene glycol/ electrolytes solution is used for:

Cleaning out the bowel before a certain medical procedure (colonoscopy).

Polyethylene glycol/electrolytes solution is a laxative. It works by causing the colon to move contents along more quickly.

Do NOT use polyethylene glycol/ electrolytes solution if:

  • you are allergic to any ingredient in polyethylene glycol/electrolytes solution
  • you have certain stomach or bowel problems (eg, blockage, retention, perforation, toxic inflammation, megacolon, ileus)
  • you have abnormal blood electrolyte levels (eg, potassium, sodium, magnesium)
  • you are using other laxatives or bowel cleansing products

Contact your doctor or health care provider right away if any of these apply to you.

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Before using polyethylene glycol/ electrolytes solution:

Some medical conditions may interact with polyethylene glycol/electrolytes solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of blood electrolyte problems, seizures, kidney problems, gout, or stomach or bowel problems (eg, inflammatory bowel disease, ulcerative colitis)
  • if you have a history of irregular heartbeat (eg, prolonged QT), a recent heart attack, a certain type of chest pain (unstable angina), or other heart problems (eg, congestive heart failure, heart muscle problems)
  • if you have an impaired gag reflex, trouble swallowing, or gastric reflux, or you are at risk of aspiration (inhaling foreign matter into the airway or lungs)
  • if you are dehydrated or on a low-salt (sodium) diet
  • if you drink alcohol or you are having withdrawal symptoms from stopping alcohol or benzodiazepines (eg, diazepam)
  • if you also take medicines for blood pressure, heart problems, kidney problems, or seizures
  • if you take any medicine that may increase the risk of seizures, irregular heartbeat, or kidney problems. Check with your doctor or pharmacist if you are unsure if any of your medicines may increase the risk of these problems

Some MEDICINES MAY INTERACT with polyethylene glycol/electrolytes solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Antipsychotics (eg, olanzapine), carbamazepine, selective serotonin reuptake inhibitors (eg, fluoxetine), or tricyclic antidepressants (eg, amitriptyline) because the risk of seizures may be increased
  • Angiotensin-converting enzyme (ACE) inhibitors (eg, lisinopril), angiotensin receptor blockers (ARBs) (eg, losartan), corticosteroids (eg, prednisone), digoxin, diuretics (eg, furosemide, hydrochlorothiazide), nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen, naproxen), or other laxatives or bowel cleansing products because they may increase the risk of polyethylene glycol/electrolytes solution's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if polyethylene glycol/electrolytes solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use polyethylene glycol/ electrolytes solution:

Use polyethylene glycol/electrolytes solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Polyethylene glycol/electrolytes solution comes with an extra patient information sheet called a Medication Guide. It also comes with detailed instructions for use. Read them carefully. Ask your doctor, nurse, or pharmacist any questions that you may have about polyethylene glycol/electrolytes solution.
  • Each bottle in this kit must be mixed with water before drinking. Do not take polyethylene glycol/electrolytes solution if it has not been mixed with water.
  • Your doctor will tell you when to start using polyethylene glycol/electrolytes solution.
  • Do not eat any solid foods or drink milk or alcohol on the day before your colonoscopy and until after your colonoscopy. Drink only clear liquids before, during, and after you take polyethylene glycol/electrolytes solution. Do not eat or drink anything colored red or purple.
  • Do not eat or drink anything 2 hours before your colonoscopy.
  • Drinking extra fluids before, during, and after you take polyethylene glycol/electrolytes solution is recommended. Check with your doctor for instructions.
  • Medicines taken by mouth within 1 hour of the start of the solution may not be absorbed or be effective. Contact your doctor or pharmacist with any concerns you might have about taking your other medicines.
  • If you miss a dose of polyethylene glycol/electrolytes solution, take it as soon as you remember. Continue to take it as directed by your doctor. Notify your doctor right away if you are unable to finish taking polyethylene glycol/electrolytes solution before your test.

Ask your health care provider any questions you may have about how to use polyethylene glycol/electrolytes solution.

Important safety information:

  • If you experience stomach discomfort, pain, or bloating, you may need to stop the solution for a short time or allow a longer time between doses. Check with your doctor or pharmacist for more information. Notify your doctor right away if you are unable to finish taking polyethylene glycol/electrolytes solution before your test.
  • Contact your doctor right away if severe vomiting or diarrhea occurs, or if you become dehydrated after taking polyethylene glycol/electrolytes solution. These effects may lead to abnormal blood electrolyte levels, which may cause certain serious side effects (eg, irregular heartbeat, kidney problems, seizures). Discuss any questions or concerns with your doctor.
  • Do not use any other laxative products or enemas while you are using polyethylene glycol/electrolytes solution.
  • Lab tests, including blood electrolyte levels, heart function, and kidney function, may be performed while you use polyethylene glycol/electrolytes solution. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Polyethylene glycol/electrolytes solution should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using polyethylene glycol/electrolytes solution while you are pregnant. It is not known if polyethylene glycol/electrolytes solution is found in breast milk. If you are or will be breast-feeding while you use polyethylene glycol/electrolytes solution, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of polyethylene glycol/ electrolytes solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Discomfort; feeling of being full or bloated; mild stomach pain, cramping, or discomfort; nausea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); decreased urination; fainting; irregular heartbeat; rectal bleeding; seizures; severe or persistent nausea; severe or persistent stomach pain, bloating, cramping, or discomfort; symptoms of dehydration (eg, very dry mouth or eyes, increased thirst, fast heartbeat, dizziness, headache, sluggishness); vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of polyethylene glycol/electrolytes solution:

Store polyethylene glycol/electrolytes solution at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. After mixing the solution, it may be stored in the refrigerator. Use the solution within 48 hours. Discard any unused portion of polyethylene glycol/electrolytes solution. Keep polyethylene glycol/electrolytes solution out of the reach of children and away from pets.

General information:

  • If you have any questions about polyethylene glycol/electrolytes solution, please talk with your doctor, pharmacist, or other health care provider.
  • Polyethylene glycol/electrolytes solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take polyethylene glycol/electrolytes solution or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about polyethylene glycol/electrolytes solution. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to polyethylene glycol/electrolytes solution. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using polyethylene glycol/electrolytes solution.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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