Polyethylene Glycol 3350 With Electrolytes Dosage

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Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Bowel Preparation

240 mL (8 fluid ounces) orally every 10 minutes until 4 liters are consumed or rectal effluent is clear. In cases requiring nasogastric administration, a rate of 20 to 30 mL per minute is recommended.

Suclear (R)
1)Split-Dose (2-Day) Regimen (Preferred Method):
Dose 1: Evening before the colonoscopy (10 to 12 hours prior to dose 2):
-Pour entire contents of the 6 oz oral solution bottle into the 16 oz mixing container and then fill to the fill line with cool water and mix
-Drink the entire solution in the container within 20 minutes
-Refill the container with 16 oz of water to the fill line and drink it over the next 2 hours
-Refill the container with another 16 oz of water and drink it before going to bed

Dose 2: Next morning at least 3 and 1/2 hours prior to colonoscopy:
-Dissolve the powder by adding water to the fill line on the jug.
-Shake the jug until all powder is dissolved.
-Using the 16 oz container provided, drink all the solution in the jug at a rate of one 16 oz container every 20 minutes.
-Refill the container to the fill line with 16 oz of water and finish drinking it before bed.
-Complete drinking the solution at least 2 hours before the colonoscopy.
-Consume only clear liquids until 2 hours prior to colonoscopy. Then nothing should be consumed until after the colonoscopy.

2)Day Before (1 Day) Regimen (Alternative Method):
Dose 1: Evening before colonoscopy (Begin 3 and 1/2 hours before bedtime):
-Pour entire contents of the 6 oz oral solution bottle into the 16 oz mixing container and then fill to the fill line with cool water and mix.
-Drink the entire solution in the container within 20 minutes.
-Refill the container with 16 oz of water to the fill line and drink it over the next 2 hours.

Dose 2 (Approximately 2 hours after Dose 1):
-Dissolve the powder by adding water to the fill line on the jug.
-Shake the jug until all powder is dissolved.
-Using the 16 oz container provided, drink all the solution in the jug at a rate of one 16 oz container every 20 minutes.
-Complete drinking the solution at least 2 hours before the colonoscopy.
-Consume only clear liquids until 2 hours prior to colonoscopy. Then nothing should be consumed until after the colonoscopy.

Comments: Dose 2 solution can be used with or without flavor packets. When dissolved in water the Dose 2 solution should be clear and colorless. The Dose 2 solution may be refrigerated but should be used within 48 hours.

Moviprep (R)
1)Split-dose regimen:
-The evening before the procedure take the first liter of solution over one hour (8 ounces every 15 minutes) and then drink 0.5 liters (16 ounces) of clear liquid.
-The morning of the procedure take the second liter of solution over one hours and then drink 0.5 liters of clear liquid at least one hour prior to the start of the procedure

2)Evening only (full-dose) regimen:
-Around 6 PM in the evening, take the first liter of solution over one hour (8 ounces every 15 minutes) and then 1.5 hours later take the second liter of solution over one hour. In addition, take 1 liter (32 ounces) of additional clear liquid during the evening before the procedure.

Comments:
-Solution is prepared by emptying the contents of 1 pouch A and 1 pouch B into a suitable container and adding 1 liter of lukewarm water.
-Mix solution until all ingredients completely dissolved
-No additional ingredients should be added
-Solution can be refrigerated
-Reconstituted solutions should be used within 24 hours

Usual Adult Dose for Gastrointestinal Decontamination

1 to 2 liters per hour orally or via nasogastric tube until the effluent is clear. Polyethylene glycol electrolyte solution is sometimes administered in combination with activated charcoal, however, charcoal adsorption may occur.

Usual Adult Dose for Constipation - Chronic

240 to 480 mL (8 to 16 fluid ounces) orally once a day.

Renal Dose Adjustments

No adjustment recommended; use with caution

Liver Dose Adjustments

No adjustment recommended

Precautions

Consult WARNINGS section for dosing related precautions.

Dialysis

No adjustment recommended

Other Comments

Administration advice: Each bottle needs to be diluted in water before ingestion; direct ingestion of the undiluted solution may increase the risk of nausea, vomiting, and dehydration. Oral medications may not be absorbed properly if they are taken within one hour of starting each dose. Solid food should not be given within 2 hours of administration of the solution. The addition of sweeteners or other additives to the solution may alter the osmolality or cause the formation of explosive gas.

Reconstitution/preparation techniques: Refer to the manufacturer's product information.

General: Administration of the PEG-ELS is best accomplished when given to a patient capable of sitting on a commode. When given to an unconscious patient, or one that is unable to sit on a commode, a rectal tube may be placed to drain the effluent.

Patient advice: Consume only clear liquids (no solid food or milk). Do not eat or drink anything red or purple. Do not to take other laxatives. Avoid alcohol on the day before colonoscopy until after completion of the colonoscopy. Stay adequately hydrated before, during, and after treatment.

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