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Generic Name: nadolol (NAY-doe-lol)
Brand Name: Corgard

Do not suddenly stop taking nadolol. Sharp chest pain, irregular heartbeat, and sometimes heart attack may occur if you suddenly stop nadolol. The risk may be greater if you have certain types of heart disease. Your doctor should slowly lower your dose over several weeks if you need to stop taking it. This should be done even if you only take nadolol for high blood pressure. Heart disease is common and you may not know you have it. Limit physical activity while you are lowering your dose. If new or worsened chest pain or other heart problems occur, contact your doctor right away. You may need to start taking nadolol again.


Nadolol is used for:

Long-term management of angina (chest pain). It is also used alone or with other medicines to treat high blood pressure. It may also be used for other conditions as determined by your doctor.

Nadolol is a beta-blocker. It works by slowing down the heart and decreasing the amount of blood it pumps out. This helps to decrease blood pressure, helps the heart pump more efficiently, and reduces the workload on the heart.

Do NOT use nadolol if:

  • you are allergic to any ingredient in nadolol
  • you have asthma, uncontrolled heart failure, shock caused by serious heart problems, a very slow heartbeat, or certain types of irregular heartbeat (eg, heart block)
  • you are taking mibefradil

Contact your doctor or health care provider right away if any of these apply to you.

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Before using nadolol:

Some medical conditions may interact with nadolol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of lung or breathing problems (eg, chronic obstructive pulmonary disease [COPD], bronchitis), diabetes, heart problems (eg, congestive heart failure, slow or irregular heartbeat), overactive thyroid, kidney problems, blood vessel problems, or a tumor on your adrenal gland (pheochromocytoma)
  • if you are scheduled to have surgery or receive anesthesia

Some MEDICINES MAY INTERACT with nadolol. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Mibefradil because the risk of serious heart side effects may be increased
  • Many prescription and nonprescription medicines (eg, used for infections, inflammation, aches and pains, high blood pressure, heart problems, irregular heartbeat, diabetes, depression, mental or mood problems, immune system suppression, allergic reactions, asthma or other lung or breathing problems, high cholesterol, seizures, multiple sclerosis [MS]), multivitamin products, and herbal or dietary supplements (eg, herbal teas, garlic, ginseng, ginkgo, St. John's wort) may interact with nadolol, increasing the risk of side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if nadolol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use nadolol:

Use nadolol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take nadolol by mouth with or without food.
  • Take nadolol on a regular schedule to get the most benefit from it. Taking nadolol at the same time each day will help you remember to take it.
  • Continue to take nadolol even if you feel well. Do not miss any doses.
  • Do not suddenly stop taking nadolol. You may have an increased risk of side effects. If you need to stop nadolol, your doctor will gradually lower your dose.
  • If you miss a dose of nadolol, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use nadolol.

Important safety information:

  • Nadolol may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use nadolol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.
  • Do not take more than the recommended dose or change your dose without checking with your doctor.
  • Do not suddenly stop taking nadolol without talking with your doctor. Sharp chest pain, irregular heartbeat, and sometimes a heart attack may occur if you suddenly stop nadolol. The risk may be greater if you have certain types of heart disease. The dose should be reduced gradually over a period of several weeks if you need to stop taking it. If new or worsened chest pain or other heart problems develop, contact your doctor right away. You may need to start taking nadolol again.
  • If your doctor has instructed you to check your blood pressure and heart rate regularly, be sure to do so.
  • Tell your doctor or dentist that you take nadolol before you receive any medical or dental care, emergency care, or surgery.
  • If you have high blood pressure, do not use nonprescription products that contain stimulants. These products may include diet pills or cold medicines. Contact your doctor if you have any questions or concerns.
  • If you have a history of any severe allergic reaction, talk with your doctor. You may be at risk of an even more severe allergic reaction if you come into contact with the substance that caused your allergy. Some medicines used to treat severe allergies may also not work as well while you are using nadolol.
  • Diabetes patients- Nadolol may hide signs of low blood sugar, such as a rapid heartbeat. Be sure to watch for other signs of low blood sugar. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your vision change; give you a headache, chills, or tremors; or make you hungrier. Nadolol may also affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Lab tests, including blood pressure, electrocardiogram (ECG), heart rate, and heart function tests, may be performed while you use nadolol. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Nadolol should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using nadolol while you are pregnant. Nadolol is found in breast milk. Do not breast-feed while taking nadolol.

If you stop taking nadolol suddenly, you may have WITHDRAWAL symptoms. These may include fast heartbeat, low blood pressure, chest pain, and nervousness.

Possible side effects of nadolol:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness or tiredness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); behavior changes; blurred vision or other vision changes; burning, numbness, or tingling; fainting; fever, chills, or persistent sore throat; hallucinations; severe or persistent dizziness or light-headedness; short-term memory problems; shortness of breath; slow or irregular heartbeat; sudden, unexplained weight gain; swelling of the hands, ankles, or feet; unusual bruising or bleeding.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include difficulty breathing; fainting; light-headedness; severe dizziness; shortness of breath; slow heartbeat; sudden, unexplained weight gain; swelling of the hands, ankles, or feet.

Proper storage of nadolol:

Store nadolol at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep bottle tightly closed. Keep nadolol out of the reach of children and away from pets.

General information:

  • If you have any questions about nadolol, please talk with your doctor, pharmacist, or other health care provider.
  • Nadolol is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take nadolol or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about nadolol. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to nadolol. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using nadolol.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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