Magnesium salicylate

Generic Name: magnesium salicylate (mag-NEE-zee-uhm sal-i-SIL-ate)
Brand Name: Examples include Doan's Pills and DeWitt's Pain Reliever

Magnesium salicylate is used for:

Treating minor backache pain. It may also be used for other conditions as determined by your doctor.

Magnesium salicylate is a salicylate. It works by blocking certain chemicals in the body that cause pain, inflammation, and fever.

Do NOT use magnesium salicylate if:

  • you are allergic to any ingredient in magnesium salicylate or you have had a severe allergic reaction (eg, severe rash, hives, breathing difficulties, dizziness) to aspirin or an NSAID (eg, ibuprofen, naproxen, celecoxib)
  • you are a child or teenager with influenza (flu) or chickenpox
  • you have bleeding problems such as hemophilia, von Willebrand disease, or low blood platelets
  • you are taking anticoagulants (eg, heparin, warfarin) or methotrexate

Contact your doctor or health care provider right away if any of these apply to you.

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Before using magnesium salicylate:

Some medical conditions may interact with magnesium salicylate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have alcoholism or if you consume 3 or more alcohol-containing drinks every day
  • if you have asthma, bleeding or clotting problems, diabetes, gout, arthritis, growths in the nose (nasal polyps), kidney or liver problems, stomach or peptic ulcers (bleeding ulcers), heartburn, upset stomach, stomach pain, influenza (flu) or chickenpox, or vitamin K deficiency
  • if you have a history of stroke or a weakened blood vessel (cerebral aneurysm) or bleeding in the brain
  • if you have Kawasaki syndrome (a rare inflammation causing heart problems in children)

Some MEDICINES MAY INTERACT with magnesium salicylate. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Carbonic anhydrase inhibitors (eg, acetazolamide) because they may decrease magnesium salicylate's effectiveness
  • Anticoagulants (eg, heparin, warfarin) or NSAIDs (eg, ibuprofen, celecoxib) because the risk of their side effects, including risk of bleeding, may be increased by magnesium salicylate
  • Insulin and oral antidiabetics (eg, glyburide, nateglinide) because the risk of their side effects, including abnormally low blood sugar level (eg, hunger, shakiness or weakness, dizziness, headache, sweating), may be increased by magnesium salicylate
  • Methotrexate or valproic acid because the risk of their side effects may be increased by magnesium salicylate
  • Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), probenecid, or sulfinpyrazone because their effectiveness may be decreased by magnesium salicylate

This may not be a complete list of all interactions that may occur. Ask your health care provider if magnesium salicylate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use magnesium salicylate:

Use magnesium salicylate as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take magnesium salicylate by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Take magnesium salicylate with a full glass of water (8 oz/240 mL). Do not lie down for 30 minutes after taking magnesium salicylate.
  • Use magnesium salicylate exactly as directed on the package, unless instructed differently by your doctor. If you are taking magnesium salicylate without a prescription, follow any warnings and precautions on the label.
  • If you miss a dose of magnesium salicylate and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use magnesium salicylate.

Important safety information:

  • Talk to your doctor before you take magnesium salicylate if you drink more than 3 drinks with alcohol per day.
  • Magnesium salicylate may cause stomach bleeding. Your risk may be greater if you drink alcohol while you are using magnesium salicylate.
  • Magnesium salicylate may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
  • Magnesium salicylate has a salicylate in it. Before you start any new medicine, check the label to see if it has a salicylate in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Magnesium salicylate has a salicylate in it, which has been linked to a serious illness called Reye syndrome. Do not give magnesium salicylate to a child or teenager who has the flu, chickenpox, or a viral infection. Contact your doctor with any questions or concerns.
  • If magnesium salicylate has a strong vinegar-like smell upon opening, do not use. It means the medicine is breaking down. Throw the bottle away safely and out of the reach of children; contact your pharmacist and replace.
  • Tell your doctor or dentist that you take magnesium salicylate before you receive any medical or dental care, emergency care, or surgery.
  • Do not take magnesium salicylate for at least 7 days after any surgery unless directed by your health care provider.
  • Do not take magnesium salicylate for more than 10 days for pain or for more than 3 days for fever unless directed to do so by your health care provider.
  • Different brands of magnesium salicylate may have different dosing instructions for CHILDREN. Follow the dosing instructions on the package labeling. If your doctor has given you instructions, follow those. If you are unsure of the dose to give a child, check with your doctor or pharmacist.
  • PREGNANCY and BREAST-FEEDING: Do not use magnesium salicylate during the last 3 months of pregnancy; it may cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using magnesium salicylate while you are pregnant. Magnesium salicylate is found in breast milk. If you are or will be breast-feeding while you use magnesium salicylate, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of magnesium salicylate:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Heartburn; nausea; upset stomach.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black or bloody stools; confusion; diarrhea; dizziness; drowsiness; hearing loss; ringing in the ears; severe stomach pain; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include agitation; fever; hearing loss; lethargy; lightheadedness, especially upon standing; nausea; rapid breathing; rapid or irregular heartbeat; ringing in the ears; seizures; shortness of breath; stomach pain; vomiting.

Proper storage of magnesium salicylate:

Store magnesium salicylate at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep magnesium salicylate out of the reach of children and away from pets.

General information:

  • If you have any questions about magnesium salicylate, please talk with your doctor, pharmacist, or other health care provider.
  • Magnesium salicylate is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take magnesium salicylate or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about magnesium salicylate. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to magnesium salicylate. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using magnesium salicylate.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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