Iopidine drops

Generic Name: apraclonidine (app-rah-KLOE-nih-deen)
Brand Name: Iopidine

Iopidine drops is used for:

Controlling or preventing high fluid pressure within the eye in patients who are already using other medicines and need further lowering of the pressure in the eye.

Iopidine drops is an alpha-adrenergic agonist. It works by decreasing fluid formation inside the eye, which helps to lower the pressure inside the eye.

Do NOT use Iopidine drops if:

  • you are allergic to any ingredient in Iopidine drops or to similar medicines (eg, clonidine)
  • you are taking or have taken a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

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Before using Iopidine drops:

Some medical conditions may interact with Iopidine drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have recently had a heart attack or you have a history of heart disease or other heart problems, high or low blood pressure, blood vessel problems, brain blood vessel problems (eg, stroke), kidney problems, or liver problems
  • if you have a history of rapid fall in heart rate or blood pressure

Some MEDICINES MAY INTERACT with Iopidine drops. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Barbiturates (eg, phenobarbital), narcotic pain medicine (eg, codeine), or tricyclic antidepressants (eg, amitriptyline) because the risk of drowsiness may be increased
  • Beta-blocker eye drops (eg, timolol), beta-blockers (eg, propranolol), digoxin, or medicines for high blood pressure because side effects such as low blood pressure and slow heartbeat may be increased by Iopidine drops
  • MAO inhibitors (eg, phenelzine) because the risk of high blood pressure may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Iopidine drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Iopidine drops:

Use Iopidine drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Iopidine drops is for use in the eye only. Avoid contact with other mucous membranes.
  • To use Iopidine drops, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them. To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.
  • Wait 5 minutes before using any additional eye drop medicines to prevent Iopidine drops from being washed out of the eye.
  • If you miss a dose of Iopidine drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Iopidine drops.

Important safety information:

  • Iopidine drops may cause drowsiness, dizziness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Iopidine drops. Using Iopidine drops alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Iopidine drops. Iopidine drops will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
  • Iopidine drops may be harmful if swallowed. If you or someone you know may have taken Iopidine drops by mouth, contact your local poison control center or emergency room immediately.
  • Use Iopidine drops with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Iopidine drops, discuss with your doctor the benefits and risks of using Iopidine drops during pregnancy. It is unknown if Iopidine drops is excreted in breast milk. If you are or will be breast-feeding while you are using Iopidine drops, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Iopidine drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dry eye, mouth, or nose.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; dizziness; drowsiness; eye pain, redness, itching, or swelling; foreign body sensation; light sensitivity; swelling of the eyelids; tearing or discharge from the eye; weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms of oral ingestion may include drowsiness; lower body temperature (hypothermia); slow or irregular heartbeat.

Proper storage of Iopidine drops:

Store Iopidine drops between 36 and 80 degrees F (2 and 27 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Iopidine drops out of the reach of children and away from pets.

General information:

  • If you have any questions about Iopidine drops, please talk with your doctor, pharmacist, or other health care provider.
  • Iopidine drops is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Iopidine drops or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Iopidine drops. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Iopidine drops. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Iopidine drops.

Issue Date: November 5, 2014
Database Edition 14.4.1.002
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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