Generic Name: hydrocortisone (HYE-droe-KOR-ti-sone)
Brand Name: Examples include Colocort and Cortenema
Hydrocortisone enema is used for:
Treating inflammatory conditions of the colon such as ulcerative colitis and ulcerative proctitis. It may also be used for other conditions as determined by your doctor.
Hydrocortisone enema is a topical corticosteroid. It works by decreasing inflammation.
Do NOT use hydrocortisone enema if:
- you are allergic to any ingredient in hydrocortisone enema
- you are taking interleukin-2 or mifepristone, or you will be receiving a smallpox vaccine
- you have a rectal obstruction, abscess, or perforation; recent colostomy surgery; or a systemic fungal infection
Contact your doctor or health care provider right away if any of these apply to you.
Before using hydrocortisone enema:
Some medical conditions may interact with hydrocortisone enema. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a weakened immune system; a parasitic, bacterial, fungal, or viral infection; heart failure; diabetes; diarrhea; swelling of the esophagus; stomach problems; blockage of the bowel or other bowel problems; abnormal blood electrolyte (eg, potassium, sodium) levels; measles; tuberculosis (TB); chickenpox; shingles; or herpes infection of the eye; or if you have received a recent vaccination
- if you have a history of glaucoma, cataracts, or other eye problems; high blood pressure; weak bones; heart attack; ulcers; kidney problems; liver problems (eg, cirrhosis); underactive thyroid; nerve problems (eg, myasthenia gravis); or a positive TB skin test
Some MEDICINES MAY INTERACT with hydrocortisone enema. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Aprepitant, clarithromycin, or hormonal contraceptives (eg, birth control pills) because they may increase the risk of hydrocortisone enema's side effects
- Barbiturates (eg, phenobarbital), carbamazepine, hydantoins (eg, phenytoin), or rifampin because they may decrease hydrocortisone enema's effectiveness
- Anticoagulants (eg, warfarin), ritodrine, or smallpox vaccine because the risk of their side effects may be increased by hydrocortisone enema
- Interleukin-2 or mifepristone because their effectiveness may be decreased by hydrocortisone enema
This may not be a complete list of all interactions that may occur. Ask your health care provider if hydrocortisone enema may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use hydrocortisone enema:
Use hydrocortisone enema as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with hydrocortisone enema. Talk to your pharmacist if you have questions about this information.
- Shake well before each use.
- Wash your hands immediately after using hydrocortisone enema.
- Use hydrocortisone enema on a regular schedule to get the most benefit from it. Using it at the same time each day (usually at bedtime or as directed by your doctor) will help you remember to use it.
- Do not suddenly stop using hydrocortisone enema if your course of treatment lasts longer than 21 days. Your doctor will gradually lower your dose.
- If you miss a dose of hydrocortisone enema and you are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
Ask your health care provider any questions you may have about how to use hydrocortisone enema.
Important safety information:
- Do not use hydrocortisone enema for other rectal conditions at a later time.
- Tell your doctor or dentist that you take hydrocortisone enema before you receive any medical or dental care, emergency care, or surgery.
- Do not receive a live vaccine (eg, measles, mumps) while you are taking hydrocortisone enema. Talk with your doctor before you receive any vaccine.
- If you have not had chickenpox, shingles, or measles, avoid contact with anyone who does. If you are exposed to someone who has one of these conditions, contact your doctor right away.
- If your symptoms do not get better within 2 to 3 weeks or if they get worse, check with your doctor.
- Hydrocortisone enema should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they use hydrocortisone enema.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using hydrocortisone enema while you are pregnant. It is not known if hydrocortisone enema is found in breast milk. If you are or will be breast-feeding while you use hydrocortisone enema, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of hydrocortisone enema:
All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Mild irritation or dryness.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fever, chills, or persistent sore throat; mental or mood changes; new or worsening rectal pain, burning, itching, bleeding, or irritation; vision changes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Hydrocortisone enema may be harmful if swallowed.Proper storage of hydrocortisone enema:
Store hydrocortisone enema at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep hydrocortisone enema out of the reach of children and away from pets.
- If you have any questions about hydrocortisone enema, please talk with your doctor, pharmacist, or other health care provider.
- Hydrocortisone enema is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take hydrocortisone enema or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about hydrocortisone enema. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to hydrocortisone enema. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using hydrocortisone enema.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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