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Hydrocortisone Pregnancy and Breastfeeding Warnings

Hydrocortisone is also known as: A-Hydrocort, Colocort, Cortef, Cortenema, Cortifoam, Hydrocortone, Hydrocortone Phosphate, Solu-Cortef

Hydrocortisone Pregnancy Warnings

Hydrocortisone has not been assigned to an FDA pregnancy category. Animal studies involving corticosteroids have revealed evidence of an increased incidence of cleft palate in offspring. There are no controlled data in human pregnancy, however, corticosteroids have been used during human pregnancy without evidence of teratogenicity. Hydrocortisone should be given during pregnancy only when benefit outweighs risk.

See references

Hydrocortisone Breastfeeding Warnings

There are no data on the excretion of hydrocortisone into human milk. Some corticosteroids are excreted into human milk in small amounts. The manufacturer recommends against the use of pharmacologic doses of hydrocortisone by nursing women.

See references

References for pregnancy information

  1. Zuspan FR, Cordero L, Semchyshyn S "Effects of hydrocortisone on lecithin-sphingomyelin ratio." Am J Obstet Gynecol 128 (1977): 571-4
  2. "Product Information. Hydrocortone (hydrocortisone)." Merck & Co, Inc, West Point, PA.
  3. Houlihan CM, Knuppel RA, Vintzileos AM, Guo JZ, Hahn DW "The effect of specific hormones on fibrinolysis in pregnancy." Am J Obstet Gynecol 175 (1996): 168-72
  4. Wilson EA, Jawad MJ "Stimulation of human chorionic gonadotropin secretion by glucocorticoids." Am J Obstet Gynecol 142 (1982): 344-9
  5. Whitt GG, Buster JE, Killam AP, Scragg WH "A comparison of two glucocorticoid regimens for acceleration of fetal lung maturation in premature labor." Am J Obstet Gynecol 124 (1976): 479-82
  6. Tan SL, Balen A, el Hussein E, Campbell S, Jacobs HS "The administration of glucocorticoids for the prevention of ovarian hyperstimulation syndrome in in vitro fertilization: a prospectiv randomized study." Fertil Steril 58 (1992): 378-83

References for breastfeeding information

  1. "Product Information. Hydrocortone (hydrocortisone)." Merck & Co, Inc, West Point, PA.

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