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Eflornithine cream

Generic Name: eflornithine (eh-FLOOR-neh-theen)
Brand Name: Vaniqa

Eflornithine cream is used for:

Slowing the growth of unwanted facial hair in women.

Eflornithine cream is an enzyme inhibitor. It works by blocking an enzyme necessary for hair to grow.

Do NOT use eflornithine cream if:

  • you are allergic to any ingredient in eflornithine cream

Contact your doctor or health care provider right away if any of these apply to you.

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Before using eflornithine cream:

Some medical conditions may interact with eflornithine cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have scraped or broken skin, or sores on the affected area

Some MEDICINES MAY INTERACT with eflornithine cream. However, no specific interactions with eflornithine cream are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if eflornithine cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use eflornithine cream:

Use eflornithine cream as directed by your doctor. Check the label on the medicine for exact dosing instructions. Check the label on the medicine for exact dosing instructions.

  • Eflornithine cream comes with an additional patient leaflet. Read it carefully and reread it each time you get eflornithine cream refilled. Ask your doctor or pharmacist any questions that you may have about eflornithine cream.
  • Apply a thin layer of eflornithine cream to the affected areas of the face and under the chin, at least 5 minutes after hair removal (eg, plucking, shaving). Rub in thoroughly. Do not wash the treated area for at least 4 hours. Wait at least 8 hours between applications of eflornithine cream.
  • Cosmetics or sunscreens may be applied to treated areas after eflornithine cream has dried.
  • If you miss a dose of eflornithine cream, skip the missed dose and return to your regular dosing schedule. Do not apply 2 doses at once.

Ask your health care provider any questions you may have about how to use eflornithine cream.

Important safety information:

  • Eflornithine cream is for external use only. Avoid contact with the vaginal area, eyes, nose, or mouth.
  • Eflornithine cream does not remove hair. You will need to continue your routine method of hair removal while using eflornithine cream.
  • You may need to use eflornithine cream for at least 4 to 8 weeks before you begin to see improvement. If your symptoms do not improve or become worse, contact your doctor.
  • Use eflornithine cream with extreme caution in CHILDREN younger than 12 years of age. Safety and effectiveness in this age group have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using eflornithine cream during pregnancy. It is unknown if eflornithine cream is excreted in breast milk. If you are or will be breast-feeding while you are using eflornithine cream, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of eflornithine cream:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Redness; skin tingling; temporary stinging or burning.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bleeding or irritation of the skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Eflornithine cream may be harmful if swallowed. Symptoms may include dizziness; facial swelling; hair loss; headache; hearing loss; loss of appetite; seizures; unusual bruising or bleeding; upset stomach; weakness.

Proper storage of eflornithine cream:

Store eflornithine cream at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Do not freeze. Store away from heat, moisture, and light. Do not store in the bathroom. Keep eflornithine cream out of the reach of children and away from pets.

General information:

  • If you have any questions about eflornithine cream, please talk with your doctor, pharmacist, or other health care provider.
  • Eflornithine cream is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take eflornithine cream or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about eflornithine cream. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to eflornithine cream. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using eflornithine cream.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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