Generic Name: desmopressin (DES-moe-PRES-in)
Brand Name: DDAVP
Desmopressin tube is used for:
Managing temporarily increased thirst and urination caused by head injury or certain types of brain surgery, or to manage certain types of diabetes (cranial diabetes insipidus). It may also be used for other conditions as determined by your doctor.
Desmopressin tube is an antidiuretic hormone. It works by causing the kidneys to produce less urine.
Do NOT use desmopressin tube if:
- you are allergic to any ingredient in desmopressin tube
- you have moderate to severe kidney problems
- you have or have a history of low blood sodium levels (salt depletion)
Contact your doctor or health care provider right away if any of these apply to you.
Before using desmopressin tube:
Some medical conditions may interact with desmopressin tube. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have nasal problems (eg, scarring, swelling, congestion, blockage, discharge, severe runny nose) or a history of nasal surgery
- if you have severe drowsiness
- if you have a history of kidney problems, heart attack or other heart problems (eg, heart blood vessel problems, heart failure), blood clots (eg, in the legs, lungs, eyes), blood circulation problems, stroke, high or low blood pressure, blood electrolyte problems (eg, low blood sodium levels), swelling or fluid retention, or a condition that causes you to be very thirsty
- if you have cystic fibrosis, dehydration, fever, severe infection, or vomiting or diarrhea
- if you are exposed to very hot weather, are physically active, or drink a lot of water or fluids
- if you have recently had surgery in the head area
- if you take antihistamines (eg, diphenhydramine) or medicines to treat blood pressure or heart problems
Some MEDICINES MAY INTERACT with desmopressin tube. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Carbamazepine, chlorpromazine, lamotrigine, narcotic analgesics (eg, codeine), nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), oxybutynin, selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), or tricyclic antidepressants (eg, imipramine) because the risk of fluid overload with low blood sodium levels may be increased
Ask your health care provider if desmopressin tube may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use desmopressin tube:
Use desmopressin tube as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with desmopressin tube. Talk to your pharmacist if you have questions about this information.
- Desmopressin tube should only be used in the nose. Do not get it in your eyes or mouth. If you get it in your eyes, rinse at once with cool tap water.
- Open desmopressin tube by pulling the plastic tag on the neck of the dropper bottle. Break the security seal and remove the plastic cap. Twist off the small, ridged seal from the top of the dropper. Save this to reseal the bottle to prevent leakage between doses.
- Fill the soft plastic rhinal tube (nose tube) with the correct dose of medicine. Insert the tip of the medicine dropper bottle downward into the end of the nose tube that is marked with an arrow. Squeeze the medicine from the dropper bottle into the nose tube until the medicine reaches the correct dose mark on the nose tube. Use constant pressure when squeezing the dropper bottle to avoid air bubbles in the tube. Remove the dropper bottle from the nose tube by withdrawing it quickly downward.
- For adults and older children: Hold the nose tube about Â¾ inch from the end and gently insert it into 1 nostril until the tips of your fingers touch your nose. Place the other end of the tube in your mouth. Hold your breath, tilt your head back slightly, and blow through the nose tube with a short, strong puff.
- For very young children: Place the nose tube only far enough into the child's nostril so that the medicine does not run out. An adult may need to blow the medicine into the child's nose.
- After use, replace the top of the ridged seal onto the tip of the dropper bottle. Cover the resealed dropper bottle with the plastic cap. Wash the tube in water and shake thoroughly until no more water is left. Allow the tube to air dry. It can be used again for the next dose.
- If you miss a dose of desmopressin tube, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use desmopressin tube.
Important safety information:
- Desmopressin tube may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use desmopressin tube with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Desmopressin tube may increase the risk of fluid overload and low blood sodium levels (hyponatremia). Hyponatremia may be fatal if left untreated. Children and elderly patients are at a greater risk for these conditions. Follow the fluid intake instructions given to you by your health care provider very carefully. Serious side effects, such as seizures, may occur if you drink too much fluid while taking desmopressin tube. Do not drink more than needed to satisfy your thirst. Contact your doctor right away if you experience symptoms of hyponatremia (eg, confusion; hallucinations; headache; loss of appetite; mental or mood changes, such as irritability; muscle weakness, spasms, or cramps; nausea; restlessness; seizures; sluggishness; tiredness; unusual weight gain; vomiting).
- Check with your doctor if you experience infection, fever, vomiting, or diarrhea. Tell your doctor if you will be exposed to very hot weather, will be physically active, or will be increasing your water intake for any reason. The risk of low blood sodium levels may be increased.
- Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
- Tell your doctor or dentist that you take desmopressin tube before you receive any medical or dental care, emergency care, or surgery.
- Lab tests, including urine volume or blood electrolyte levels, may be performed while you use desmopressin tube. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use desmopressin tube with caution in the ELDERLY and in CHILDREN; they may be more sensitive to its effects, especially fluid overload and low blood sodium levels. Carefully follow the fluid intake instructions given to you by your doctor.
- Desmopressin tube should be used with extreme caution in CHILDREN younger than 6 years old if used for nighttime bedwetting; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using desmopressin tube while you are pregnant. It is not known if desmopressin tube is found in breast milk. If you are or will be breast-feeding while you are using desmopressin tube, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of desmopressin tube:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Cough; facial flushing; mild stomach cramps; nosebleed; runny or stuffy nose; sore throat.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); calf or leg pain, tenderness, or swelling; chest pain; confusion; coughing up blood; fainting; fast or irregular heartbeat; hallucinations; loss of appetite; mental or mood changes (eg, agitation, irritability); muscle weakness, spasms, or cramps; nausea; numbness of an arm or leg; one-sided weakness; personality changes; recurrent or severe nosebleeds; restlessness; seizures; severe or persistent headache or dizziness; slurred speech; swelling of the hands, ankles, or feet; swelling of the head of the penis; unusual tiredness or sluggishness; unusual weight gain; vision problems; vomiting.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include confusion; drowsiness; severe or persistent headache; sudden, unexplained weight gain; trouble urinating. Desmopressin tube may be harmful if swallowed.Proper storage of desmopressin tube:
Store desmopressin tube in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Storage for up to 3 weeks at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), is permitted. Store away from heat, moisture, and light. Keep desmopressin tube out of the reach of children and away from pets.
- If you have any questions about desmopressin tube, please talk with your doctor, pharmacist, or other health care provider.
- Desmopressin tube is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take desmopressin tube or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about desmopressin tube. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to desmopressin tube. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using desmopressin tube.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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