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Vivarin Side Effects

Generic Name: caffeine

Note: This page contains side effects data for the generic drug caffeine. It is possible that some of the dosage forms included below may not apply to the brand name Vivarin.

For the Consumer

Applies to caffeine: oral capsule, oral capsule extended release, oral packet, oral powder for suspension, oral solution, oral tablet, oral tablet chewable, oral tablet enteric coated, oral tablet extended release

Other dosage forms:

As well as its needed effects, caffeine (the active ingredient contained in Vivarin) may cause unwanted side effects that require medical attention.

Severity: Major

If any of the following side effects occur while taking caffeine, check with your doctor immediately:

More common
  • Feeding intolerance
Less common
  • Agitation
  • black, tarry stools
  • blood in the stools or urine
  • bruising
  • burning feeling or tenderness in the stomach
  • chills
  • coma
  • confusion
  • coughing or vomiting blood
  • decreased urine output
  • depression
  • dizziness
  • fainting
  • fast heartbeat
  • fever
  • headache
  • hostility
  • indigestion
  • irritability
  • lethargy
  • lightheadedness
  • muscle twitching
  • nausea
  • persistent bleeding
  • rapid, shallow breathing
  • rapid weight gain
  • rash
  • seizures
  • severe stomach pain
  • stomach upset
  • stupor
  • swelling of the face, ankles, or hands
  • trouble breathing
  • unusual tiredness or weakness
  • vomiting
  • vomiting of blood or material that looks like coffee grounds

If any of the following symptoms of overdose occur while taking caffeine, get emergency help immediately:

Symptoms of overdose
  • Irritability
  • nervousness
  • rapid heartbeat
  • trouble sleeping

Severity: Minor

Some caffeine side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common
  • Rash
Less common
  • Dry skin

For Healthcare Professionals

Applies to caffeine: compounding powder, intravenous solution, oral gum, oral liquid, oral tablet, oral tablet dispersible, oral tablet extended release

Gastrointestinal

Very common (10% or more): Constipation (up to 17.4%)
Common (1% to 10%): Necrotizing enterocolitis, gastritis, GI hemorrhage, gastroesophageal reflux, dilated bowel loops
Frequency not reported: Increased gastric aspirate, GI intolerance, vomiting, regurgitation[Ref]

General

Long-term follow-up studies have not shown caffeine (the active ingredient contained in Vivarin) to adversely affect neurological development or growth parameters.[Ref]

Cardiovascular

Common (1% to 10%): Hemorrhage, tachycardia
Uncommon (0.1% to 1%): Arrhythmia
Frequency not reported: Increased left ventricular output, increased stroke volume, hypertension[Ref]

Dermatologic

Common (1% to 10%): Rash, dry skin, skin breakdown[Ref]

Hematologic

Common (1% to 10%): Disseminated intravascular coagulation, anemia
Frequency not reported: Decreased hemoglobin[Ref]

Hepatic

Common (1% to 10%): Kidney failure[Ref]

Metabolic

Common (1% to 10%): Acidosis, hyperglycemia
Frequency not reported: Hypoglycemia, temporary reduced weight gain, decreased thyroxine[Ref]

Nervous system

Common (1% to 10%): Cerebral hemorrhage
Uncommon (0.1% to 1%): Convulsions/seizures
Frequency not reported: Irritability, restlessness, jitteriness, tremors, brain injury[Ref]

Ocular

Common (1% to 10%): Retinopathy of prematurity[Ref]

Other

Common (1% to 10%): Perinatal disorder (trace aspirates, feeding intolerances), injection site reaction, sepsis, accidental injury, abnormal healing, infusion site phlebitis and inflammation
Frequency not reported: Failure to thrive, deafness[Ref]

Respiratory

Common (1% to 10%): Dyspnea, lung edema
Frequency not reported: Tachypnea[Ref]

Hypersensitivity

Rare (less than 0.1%): Hypersensitivity reaction[Ref]

Renal

Frequency not reported: Increased urine flow rate, increased creatinine clearance, increased sodium and calcium excretion[Ref]

References

1. "Product Information. Cafcit (caffeine)" Roxane Laboratories Inc, Columbus, OH.

It is possible that some side effects of Vivarin may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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