Vitamin D2 Side Effects

Generic name: ergocalciferol

Medically reviewed by Drugs.com. Last updated on Aug 5, 2023.

Note: This document contains side effect information about ergocalciferol. Some dosage forms listed on this page may not apply to the brand name Vitamin D2.

Applies to ergocalciferol: oral capsule, oral capsule liquid filled, oral liquid, oral solution, oral tablet.

Serious side effects of Vitamin D2

Along with its needed effects, ergocalciferol (the active ingredient contained in Vitamin D2) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ergocalciferol:

Incidence not known

Bloody or cloudy urine
blurred vision
decrease in height
dizziness
drowsiness
dry mouth
frequent urination
increased thirst
increased urge to urinate during the night
increased volume of pale, dilute urine
loss of appetite
nervousness
pain in the back, ribs, arms, or legs
pain in the lower back or side
pounding in the ears
slow growth in children
slow or fast heartbeat
swelling of the face, fingers, or lower legs
trouble breathing
unusual tiredness or weakness
vomiting
waking to urinate at night
weight gain

Other side effects of Vitamin D2

Some side effects of ergocalciferol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

For Healthcare Professionals

Applies to ergocalciferol: compounding powder, injectable solution, oral capsule, oral solution, oral tablet.

Metabolic

Rare (less than 0.1%): Hypercalcemia

Frequency not reported: Hypervitaminosis D^[Ref]

Hypervitaminosis D is characterized by: impairment of renal function with polyuria, nocturia, polydipsia, hypercalciuria, reversible azotemia, hypertension, nephrocalcinosis, generalized vascular calcification, or irreversible renal insufficiency which may result in death; intellectual disability; widespread calcification of the soft tissues, including the heart, blood vessels, renal tubules, and lungs; bone demineralization (osteoporosis) in adults; decline in the average rate of linear growth and increased mineralization of bones in infants and children (dwarfism), vague aches, stiffness, and weakness; nausea, anorexia, constipation; and mild acidosis, anemia, and weight loss.^[Ref]