Vitamin D2 Side Effects
Generic Name: ergocalciferol
Note: This page contains side effects data for the generic drug ergocalciferol. It is possible that some of the dosage forms included below may not apply to the brand name Vitamin D2.
It is possible that some side effects of Vitamin D2 may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
For the Consumer
Applies to ergocalciferol: oral capsules and solution
Side effects include:
Possible hypervitaminosis D effects: polyuria, nocturia, polydipsia, hypercalciuria, reversible azotemia, hypertension, nephrocalcinosis, generalized vascular calcification, irreversible renal insufficiency (may be fatal), mental retardation, widespread soft tissue calcification, osteoporosis, dwarfism, vague aches, stiffness, weakness, nausea, anorexia, constipation, mild acidosis, anemia, weight loss.
For Healthcare Professionals
Applies to ergocalciferol: compounding powder, injectable solution, oral capsule, oral solution, oral tablet
Metabolic side effects have included hypercalcemia.[Ref]
Hypercalciuria may precede hypercalcemia in patients being treated with ergocalciferol. Early signs and symptoms of hypercalcemia include headache, anorexia, nausea, vomiting, gastrointestinal disturbances, abdominal cramps, dry mouth, metallic taste, weakness, fatigue, muscle and bone pain, ataxia, tinnitus, and vertigo. Later stages of hypercalcemia may present as pruritus, mental confusion, hypertension, cardiac arrhythmias, seizures, metastatic calcification, and renal insufficiency (manifested as polyuria, nocturia, polydipsia, and proteinuria).[Ref]
1. Araugo OE, Flowers FP, Brown K "Vitamin D therapy in psoriasis." DICP 25 (1991): 835-9
2. Miller SM "New perspectives on vitamin D." Am J Med Technol 49 (1983): 27-37
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