Vaprisol Side Effects

Generic name: conivaptan

Note: This document contains side effect information about conivaptan. Some of the dosage forms listed on this page may not apply to the brand name Vaprisol.

Some side effects of Vaprisol may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to conivaptan: intravenous solution

Get emergency medical help if you have any of these signs of an allergic reaction while taking conivaptan (the active ingredient contained in Vaprisol) hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have a serious side effect such as:

• feeling like you might pass out;

• low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling);

• trouble speaking, trouble swallowing, weakness, mood changes, muscle spasm or weakness in your arms and legs, seizure;

• pain, redness, or swelling where the IV needle is placed;

• swelling, rapid weight gain; or

• pain or burning when you urinate.

Less serious side effects of conivaptan may include:

• mild fever;

• headache;

• diarrhea; or

• vomiting.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to conivaptan: intravenous solution

Local

Local side effects have included injection site reactions including erythema, pain, phlebitis, swelling, and cannulae site reactions.

Gastrointestinal

Gastrointestinal side effects have included constipation, diarrhea, dry mouth, nausea, vomiting, oral candidiasis, and thirst.

Cardiovascular

Cardiovascular side effects have included atrial fibrillation, orthostatic hypotension, hypotension, peripheral edema, and hypertension.

Metabolic

Metabolic side effects have included dehydration, hypokalemia, hypomagnesemia, and hyponatremia.

Hematologic

Hematologic side effects have included anemia.

Renal

Renal side effects have included hematuria, polyuria, and, pollakiuria.

Genitourinary

Genitourinary side effects have included urinary tract infection.

Nervous system

Nervous system side effects have included headache.

Psychiatric

Psychiatric side effects have included insomnia and confusion.

General

General side effects have included pain and pyrexia.

Endocrine

Endocrine side effects have included hypoglycemia and hyperglycemia.

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