Uvadex Side Effects
Generic name: methoxsalen
Note: This document contains side effect information about methoxsalen. Some of the dosage forms listed on this page may not apply to the brand name Uvadex.
Some side effects of Uvadex may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to methoxsalen: oral capsule
Get emergency medical help if you have any of these signs of an allergic reaction while taking methoxsalen (the active ingredient contained in Uvadex) hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Methoxsalen is expected to produce skin redness that may not occur until several hours after your UVA treatment. This redness may last for 2 or 3 days. You may also have slight swelling. These are normal effects of the medication and UVA treatment.
Call your doctor at once if you have a serious side effect such as:
severe skin redness within 24 hours after UVA treatment;
severe itching, swelling, or severe skin discomfort;
blisters, pimples, or skin rash;
blurred vision, eye pain, or seeing "halos" around lights;
feeling like you might pass out; or
worsening of your psoriasis.
Less serious side effects of methoxsalen may include:
mild skin redness, itching, or tenderness;
sleep problems (insomnia);
headache, dizziness; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For Healthcare Professionals
Applies to methoxsalen: compounding powder, injectable solution, oral capsule
Dermatologic side effects have included mild to serious skin burns, premature aging of the skin, pruritus, inflammation, erythema, rash (nonspecific), edema, extension of psoriasis, cutaneous tenderness, hypopigmentation, keratosis, folliculitis, dermal vessel damage, longer duration of epidermal and dermal abnormalities, miliaria, urticaria, vesiculation formation, and bullae formation.
Cardiovascular side effects are mostly associated with methoxsalen (the active ingredient contained in Uvadex) sterile solution and have included arrhythmia and serious (nonspecific) cardiovascular adverse experiences. Hypotension and dizziness have been associated with the sterile solution and the oral administration of methoxsalen.
Immunologic side effects associated with the sterile solution have included infections (nonspecific) and hickman catheter infections. Immunologic side effect with oral administration of methoxsalen (the active ingredient contained in Uvadex) has been herpes simplex.
Oncologic side effects have included cutaneous squamous cell cancers, malignant melanoma, and basal cell carcinoma.
Psychiatric side effects have included depression.
Gastrointestinal side effects have included unspecified gastrointestinal disturbances.
General side effects have included malaise and headache.
Ocular side effects have included cataracts.
More Uvadex resources
- Uvadex Advanced Consumer (Micromedex) - Includes Dosage Information
- Uvadex Prescribing Information (FDA)
- Methoxsalen Professional Patient Advice (Wolters Kluwer)
- 8-MOP hard-gelatin capsules MedFacts Consumer Leaflet (Wolters Kluwer)
- 8-MOP Prescribing Information (FDA)
- 8-Mop Concise Consumer Information (Cerner Multum)
- 8-Mop Advanced Consumer (Micromedex) - Includes Dosage Information
- Oxsoralen-Ultra soft-gelatin capsules MedFacts Consumer Leaflet (Wolters Kluwer)
- Oxsoralen-Ultra Prescribing Information (FDA)
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