Triamterene and hydrochlorothiazide Side Effects
Please note - some side effects for Triamterene and hydrochlorothiazide may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
Triamterene and hydrochlorothiazide Side Effects - for the Professional
Triamterene and Hydrochlorothiazide
Side effects observed in association with the use of Triamterene and Hydrochlorothiazide tablets, other combination products containing triamterene/hydrochlorothiazide, and products containing triamterene or hydrochlorothiazide include the following:
Gastrointestinal: jaundice (intrahepatic cholestatic jaundice), pancreatitis, nausea, appetite disturbance, taste alteration, vomiting, diarrhea, constipation, anorexia, gastric irritation, cramping.
Central Nervous System: drowsiness and fatigue, insomnia, headache, dizziness, dry mouth, depression, anxiety, vertigo, restlessness, paresthesias.
Cardiovascular: tachycardia, shortness of breath and chest pain, orthostatic hypotension (may be aggravated by alcohol, barbiturates or narcotics).
Renal: acute renal failure, acute interstitial nephritis, renal stones composed of triamterene in association with other calculus materials, urine discoloration.
Hematologic: leukopenia, agranulocytosis, thrombocytopenia, aplastic anemia, hemolytic anemia and megaloblastosis.
Ophthalmic: xanthopsia, transient blurred vision.
Hypersensitivity: anaphylaxis, photosensitivity, rash, urticaria, purpura, necrotizing angiitis (vasculitis, cutaneous vasculitis), fever, respiratory distress including pneumonitis.
Other: muscle cramps and weakness, decreased sexual performance and sialadenitis.
Whenever adverse reactions are moderate to severe, therapy should be reduced or withdrawn.
Altered Laboratory Findings
SERUM ELECTROLYTES: hyperkalemia, hypokalemia, hyponatremia, hypomagnesemia, hypochloremia.
CREATININE, BLOOD UREA NITROGEN: Reversible elevations in BUN and serum creatinine have been observed in hypertensive patients treated with Triamterene and Hydrochlorothiazide tablets.
GLUCOSE: hyperglycemia, glycosuria and diabetes mellitus.
SERUM URIC ACID, PBI AND CALCIUM:.
OTHER: Elevated liver enzymes have been reported in patients receiving Triamterene and Hydrochlorothiazide tablets.
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