Tazorac Side Effects

Please note - some side effects for Tazorac may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects of Tazorac - for the Consumer

Tazorac Cream

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Tazorac Cream:

Burning; dry skin; irritation; itching; peeling; redness; scaling; skin inflammation; skin pain; stinging.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe or prolonged itching, burning, redness, or peeling; sunburn; swelling of the skin, hands, or feet; worsening of psoriasis.

Tazorac Gel

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Tazorac Gel:

Bleeding; burning; cracks in skin; dry skin; irritation; itching; peeling; redness; scaling; skin discoloration; skin inflammation; skin pain; stinging.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe or prolonged itching, burning, redness, or peeling; sunburn; swelling of the skin, hands, or feet; worsening of psoriasis.

Tazorac Side Effects - for the Professional

Tazorac

In human dermal safety studies, tazarotene 0.05% and 0.1% gels did not induce allergic contact sensitization, phototoxicity or photoallergy.

Psoriasis:

The most frequent adverse events reported with Tazorac® Gel 0.05% and 0.1% were limited to the skin. Those occurring in 10 to 30% of patients, in descending order, included pruritus, burning/stinging, erythema, worsening of psoriasis, irritation, and skin pain. Events occurring in 1 to 10% of patients included rash, desquamation, irritant contact dermatitis, skin inflammation, fissuring, bleeding and dry skin. Increases in “psoriasis worsening” and “sun-induced erythema” were noted in some patients over the 4th to 12th months as compared to the first three months of a 1 year study. In general, the incidence of adverse events with Tazorac® Gel 0.05% was 2 to 5% lower than that seen with Tazorac® Gel 0.1%.

Acne:

The most frequent adverse events reported with Tazorac® Gel 0.1% in the treatment of acne occurring in 10 to 30% of patients, in descending order, included desquamation, burning/stinging, dry skin, erythema and pruritus. Events occurring in 1 to 10% of patients included irritation, skin pain, fissuring, localized edema and skin discoloration.

Side Effects by Body System

Dermatologic

Dermatologic side effects in up to 10% to 30% of patients include pruritus, burning/stinging, erythema, worsening of psoriasis, irritation, desquamation, dry skin, and skin pain. Side effects in up to 1% to 10% include rash, irritant contact dermatitis, skin inflammation, fissuring, bleeding, localized edema, and skin discoloration. Psoriasis worsening and sun induced erythema have also been reported.

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