Tazarotene topical Pregnancy and Breast Feeding Warnings
Tazarotene topical is also known as: Avage, Tazorac
Overview
Do not use Tazarotene Gel if you are pregnant. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Tazarotene Gel is found in breast milk. Do not breast-feed while taking Tazarotene Gel.
Tazarotene topical Pregnancy Warnings
Tazarotene has been assigned to pregnancy category X by the FDA. Animal studies have revealed reduced fetal body weights, reduced skeletal ossification, single incidences of known retinoid malformations, including spina bifida, hydrocephaly, and heart anomalies. There are no controlled data in human pregnancy. Six women inadvertently exposed to the drug during pregnancy in clinical trials gave birth to healthy babies. Tazarotene is considered contraindicated during pregnancy.
It is recommended that women of childbearing potential receive a negative result for a pregnancy test (having a sensitivity down to at least 50 milli-international units/mL for hCG) within two weeks before the initiation of tazarotene therapy. Use of birth control measures is recommended if tazarotene is to be used in women of childbearing potential.
Tazarotene topical Lactation Warnings
There are no data on the excretion of tazarotene into human milk.
Animal studies have reported that radioactivity was detected in milk after a single dose of radioactive tazarotene was applied to the skin of lactating rats.
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