Syprine Side Effects
Generic Name: trientine
Note: This document contains side effect information about trientine. Some of the dosage forms listed on this page may not apply to the brand name Syprine.
Some side effects of Syprine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to trientine: oral capsule
Along with its needed effects, trientine (the active ingredient contained in Syprine) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur while taking trientine:More common - Symptoms of anemia
- Unusually pale skin
- unusual tiredness
- general feeling of discomfort, illness, or weakness
- joint pain
- skin rash, blisters, hives, or itching
- swollen glands
Note: Signs of anemia are more likely to occur in children, menstruating women, and pregnant women, who usually need more iron than other patients. If these signs appear during trientine treatment, your doctor will need to do some tests.
For Healthcare Professionals
Applies to trientine: oral capsule
Central nervous system side effects have included dystonia, malaise, myasthenia gravis, and weakness.
Immunologic side effects have included systemic lupus erythematosus.
Hematologic side effects have included iron deficiency and hypochromic microytic anemia. The hypochromic microytic anemia was reported in 4 patients being treated with trientine (the active ingredient contained in Syprine) who had primary biliary cirrhosis.
Musculoskeletal system side effects have included muscle spasm, muscle pain, cramps, and rhabdomyolysis. The rhabdomyolysis was reported in 4 patients being treated with trientine (the active ingredient contained in Syprine) who had primary biliary cirrhosis.
Gastrointestinal side effects have included heartburn, epigastric pain and tenderness, acute gastritis, aphthoid ulcers, abdominal pain, melena, and anorexia. These side effects were reported in 4 patients being treated with trientine (the active ingredient contained in Syprine) who had primary biliary cirrhosis.
Dermatologic side effects have included thickening, fissuring, and flaking of the skin. These side effects were reported in 4 patients being treated with trientine (the active ingredient contained in Syprine) who had primary biliary cirrhosis.
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