Sogroya Side Effects

Generic name: somapacitan-beco

Medically reviewed by Drugs.com. Last updated on Dec 29, 2023.

Note: This document contains side effect information about somapacitan-beco. Some dosage forms listed on this page may not apply to the brand name Sogroya.

Applies to somapacitan-beco: subcutaneous solution.

Serious side effects of Sogroya

Along with its needed effects, somapacitan-beco (the active ingredient contained in Sogroya) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking somapacitan-beco:

More common

• Bloating
• blurred vision
• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• change in ability to see colors, especially blue or yellow
• chills
• constipation
• cough
• darkened urine
• darkening of the skin
• depressed mood
• diarrhea
• difficulty swallowing
• dizziness
• dry mouth
• dry skin and hair
• fainting
• fast heartbeat
• feeling cold
• fever
• flushed, dry skin
• fruit-like breath odor
• hair loss
• headache
• hives, itching, skin rash
• hoarseness or husky voice
• increased hunger
• increased thirst
• increased urination
• indigestion
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• loss of appetite
• loss of consciousness
• loss of fat or tissue weakness in the skin area at the injection site
• mental depression
• muscle cramps and stiffness
• nausea
• nervousness
• pains in the stomach, side, or abdomen, possibly radiating to the back
• pale skin
• persistent non-healing sore
• pink growth
• pounding in the ears
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• reddish patch or irritated area
• shiny bump
• slow or fast heartbeat
• stomach pain
• sweating
• swelling
• thickening of the skin
• tightness in the chest
• trouble breathing
• unexplained weight loss
• unusual bleeding or bruising
• unusual tiredness or weakness
• vomiting
• weight gain
• white, yellow or waxy scar-like area
• yellow eyes or skin

Other side effects of Sogroya

Some side effects of somapacitan-beco may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Acid or sour stomach
• back pain
• belching
• difficulty in moving
• heartburn
• muscle pain or stiffness
• pain in the joints
• stomach discomfort or upset
• trouble sleeping

For Healthcare Professionals

Applies to somapacitan-beco: subcutaneous solution.

General

-In pediatric patients with growth hormone deficiency (GHD): Common adverse reactions occurring in 5% or more of patients receiving this drug include nasopharyngitis, headache, fever, extremity pain, and injection site reactions.

-In adult patients with GHD: Adverse reactions occurring in over 2% of patients treated with this drug comprise back pain, joint pain, indigestion, sleep disturbances, dizziness, tonsillitis, peripheral edema, vomiting, adrenal insufficiency, high blood pressure, elevated blood creatine phosphokinase levels, weight gain, and anemia.^[Ref]

Cardiovascular

Common (1% to 10%): Hypertension^[Ref]

Dermatologic

Common (1% to 10%): Rash, urticaria

Uncommon (0.1% to 1%): Lipohypertrophy, pruritus^[Ref]

Endocrine

Common (1% to 10%): Adrenal insufficiency, hypoadrenalism, hypothyroidism^[Ref]

Gastrointestinal

Common (1% to 10%): Dyspepsia, nausea/vomiting, diarrhea, gastroenteritis

Frequency not reported: Pancreatitis^[Ref]

Nausea/vomiting included vomiting (4.5%) and nausea (1.5%); Diarrhea included diarrhea (2.3%), gastroenteritis viral (1.5%), and gastrointestinal viral infection (0.8%).^[Ref]

Hematologic

Common (1% to 10%): Anemia^[Ref]

Hypersensitivity

Frequency not reported: Severe hypersensitivity^[Ref]

Local

Common (1% to 10%): Injection site reaction

Frequency not reported: Lipohypertrophy, lipoatrophy^[Ref]

Injection site reaction included injection site bruising (1.5%), injection site pain (1.5%), injection site hematoma (1.5%), injection site reaction (0.8%), and injection site swelling (0.8%).^[Ref]

Metabolic

Very common (10% or more): Elevated phosphate (17.5%)

Common (1% to 10%): Elevated creatine phosphokinase, blood creatinine kinase increase, weight increased, hyperglycemia

Frequency not reported: Glucose intolerance, diabetes mellitus, fluid retention^[Ref]

Elevated phosphate and creatine phosphokinase occurred intermittently and were non-progressive.^[Ref]

Musculoskeletal

Very common (10% or more): Back pain (10%)

Common (1% to 10%): Arthralgia, myalgia, muscle stiffness

Uncommon (0.1% to 1%): Joint stiffness^[Ref]

Nervous system

Very common (10% or more): Headache (12.1%)

Common (1% to 10%): Sleep disorder, dizziness, paresthesia

Uncommon (0.1% to 1%): Carpal tunnel syndrome

Frequency not reported: Intracranial hypertension^[Ref]

Oncologic

Frequency not reported: Neoplasms^[Ref]

Other

Common (1% to 10%): Peripheral edema, pyrexia, fatigue, asthenia, influenza

Frequency not reported: Increased mortality in patients with acute critical illness^[Ref]

Pyrexia included pyrexia (8.3%) and hyperthermia (0.8%); pain in extremity included pain in extremity (9.1%) and growing pains (0.8%).^[Ref]

Respiratory

Nasopharyngitis included nasopharyngitis (11.4%), rhinitis (3.8%), pharyngitis streptococcal (0.8%), acute sinusitis (0.8%), nasal congestion (0.8%), pharyngitis (0.8%), and sinusitis (0.8%).^[Ref]

Very common (10% or more): Nasopharyngitis (16.7%)

Common (1% to 10%): Tonsillitis, bronchitis, upper respiratory tract infection^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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