Semprex-D Side Effects

Generic name: acrivastine / pseudoephedrine

Medically reviewed by Drugs.com. Last updated on Apr 25, 2023.

Note: This document contains side effect information about acrivastine / pseudoephedrine. Some dosage forms listed on this page may not apply to the brand name Semprex-D.

Applies to acrivastine / pseudoephedrine: oral capsule.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• fever and skin redness with small pus-filled bumps;

• fast heart rate; or

• pounding heartbeats or fluttering in your chest.

Side effects such as dizziness, drowsiness, and urination problems may be more likely in older adults.

Common side effects may include:

• dizziness, drowsiness;

• dry mouth;

• sinus pain;

• nausea; or

• headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to acrivastine / pseudoephedrine: oral capsule.

Nervous system

Very common (10% or more): Headache (19%), somnolence (12%)

Common (1% to 10%): Dizziness^[Ref]

Gastrointestinal

Common (1% to 10%): Dry mouth, nausea, dyspepsia^[Ref]

Hypersensitivity

Postmarketing reports: Serious hypersensitivity reactions (anaphylaxis, angioedema, bronchospasm, erythema multiforme)^[Ref]

Psychiatric

Common (1% to 10%): Insomnia, nervousness

Genitourinary

Common (1% to 10%): Dysmenorrhea

Respiratory

Common (1% to 10%): Pharyngitis, cough increase

Other

Common (1% to 10%): Asthenia

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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