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Drug Information
Side Effects > Norflex

Norflex Side Effects

Generic Name: Orphenadrine

Please note - some side effects for Norflex may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).


For the consumer

For the professional

Side Effects of Norflex - for the consumer


Norflex

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Norflex:

Agitation; blurred vision; constipation; dizziness or lightheadedness; drowsiness; dry mouth; headache; large pupils; nausea; stomach irritation or upset; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur when using Norflex:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chills, fever, or sore throat; confusion; fainting; fast or irregular heartbeat; hallucinations; pain, swelling, or redness the injection site; tremor; trouble urinating or inability to urinate.

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For the professional


Norflex

Adverse reactions of orphenadrine are mainly due to the mild anti-cholinergic action of orphenadrine, and are usually associated with higher dosage. Dryness of the mouth is usually the first adverse effect to appear. When the daily dose is increased, possible adverse effects include: tachycardia, palpitation, urinary hesitancy or retention, blurred vision, dilatation of pupils, increased ocular tension, weakness, nausea, vomiting, headache, dizziness, constipation, drowsiness, hypersensitivity reactions, pruritus, hallucinations, agitation, tremor, gastric irritation, and rarely urticaria and other dermatoses. Infrequently, an elderly patient may experience some degree of mental confusion. These adverse reactions can usually be eliminated by reduction in dosage. Very rare cases of aplastic anemia associated with the use of orphenadrine tablets have been reported. No causal relationship has been established.

Rare instances of anaphylactic reaction have been reported associated with the intramuscular injection of Norflex Injection.

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More resources:

Cerner Multum Norflex

MedFacts Norflex

Micromedex Norflex - Includes detailed dosage instructions.

FDA Orphenadrine

FDA Norflex

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