Norethindrone Side Effects

Brand Names: Aygestin, Camila, Errin, Jolivette, Nor-QD, Nora-BE, Ortho Micronor

Please note - some side effects for Norethindrone may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects of Norethindrone - for the Consumer

Norethindrone/Ethinyl Estradiol

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Norethindrone/Ethinyl Estradiol:

Breast tenderness; bleeding between menstrual periods; change in vaginal mucus; headache; loss of scalp hair; nausea; nervousness; rash; spotty darkening of the skin (especially on the face); stomach cramps and bloating; vaginal infection; vomiting; weight or appetite change.

Seek medical attention right away if any of these SEVERE side effects occur when using Norethindrone/Ethinyl Estradiol:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); breast lumps; calf or leg pain or swelling; chest pain; coughing of blood; dark urine or light-colored bowel movements; depression; dizziness or fainting; fever; heaviness in the chest; lack of energy or fatigue; loss of appetite; mood change; numbness in arm or leg; partial or complete loss of vision or other vision changes; sleeping problems; slurred speech; stomach pain or tenderness; sudden severe headache; sudden shortness of breath; swelling of the fingers or ankles; weakness on one side of the body; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Norethindrone

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Norethindrone:

Acne; changes in menstrual flow, including breakthrough bleeding, spotting, or missed periods; dizziness; drowsiness; fever; headache; hot flashes; nausea; nervousness; pain; rash; stomach pain; trouble sleeping; weakness; weight gain or loss.

Seek medical attention right away if any of these SEVERE side effects occur when using Norethindrone:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; depression; lumps in the breast or under the armpits; migraine headache; partial or complete loss of vision or changes in vision; shortness of breath; slurred speech; sudden loss of coordination; sudden or severe headache; sudden severe headache, dizziness, vomiting, or fainting; swelling of fingers or ankles; tenderness, pain, or swelling of the calf; weakness, numbness, or pain in the arms or legs; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Norethindrone/Ethinyl Estradiol (HRT)

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Norethindrone/Ethinyl Estradiol (HRT):

Diarrhea; headache; irregular vaginal bleeding or spotting; mild breast pain; mild hair loss; nausea; stomach upset, cramps, or bloating; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur when using Norethindrone/Ethinyl Estradiol (HRT):

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); breast lumps; chest pain; confusion; coughing up blood; dark urine or pale stools; dizziness or fainting; fever; heaviness in the chest; lack of energy or fatigue; loss of appetite; mental or mood change; numbness in arm or leg; pain or tenderness in the calf; persistent or recurrent abnormal vaginal bleeding; severe or persistent breast pain; shortness of breath; sleeping problems; speech problems; stomach pain or tenderness; sudden or severe headache or vomiting; swelling of the fingers or ankles; unusual vaginal discharge, itching, or odor; vision problems or changes (including partial or complete loss of vision); weakness or one-sided weakness; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Norethindrone/Ethinyl Estradiol Chewable Tablets

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Norethindrone/Ethinyl Estradiol Chewable Tablets:

Breast tenderness or enlargement; changes in appetite; changes in weight; dizziness; hair loss; headache; nausea; stomach cramps or bloating; unusual spotting or bleeding; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur when using Norethindrone/Ethinyl Estradiol Chewable Tablets:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); breast discharge; breast lumps; calf or leg pain, swelling, or tenderness; change in amount of urine produced; change in vaginal secretions; changes in vision or speech; confusion; coughing of blood; crushing chest pain or heaviness in the chest; dark-colored urine; depression; difficulty wearing contact lenses; fainting; fever; fluid retention (swelling of the fingers and ankles); light-colored bowel movements; mental or mood changes; missed menstrual period; numbness of an arm or leg; one-sided weakness; persistent or new headache or migraines; persistent or recurrent abnormal vaginal bleeding; persistent or severe dizziness; severe pain or tenderness in the stomach; shortness of breath; sudden partial or complete loss of vision; sudden severe headache or vomiting; unusual or persistent tiredness, lack of energy, or trouble sleeping; vaginal irritation or discharge; weakness; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Norethindrone Tablets

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Norethindrone Tablets:

Breast tenderness; changes in menstrual flow, including breakthrough bleeding or spotting; dizziness; headache; nausea.

Seek medical attention right away if any of these SEVERE side effects occur when using Norethindrone Tablets:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); absent or late menstrual period; chest pain; dark urine; depression; increased facial hair; lower abdominal pain; lumps in the breast or under the armpits; migraine headache; partial or complete loss of vision or changes in vision; shortness of breath; slurred speech; stomach pain; sudden loss of coordination; sudden or severe headache; swelling of fingers or ankles; tenderness, pain, or swelling of the calf; weakness, numbness, or pain in the arms or legs; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Norethindrone/Ethinyl Estradiol Tablets

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Norethindrone/Ethinyl Estradiol Tablets:

Breast tenderness; bleeding or spotting between menstrual periods; headache; nausea.

Seek medical attention right away if any of these SEVERE side effects occur when using Norethindrone/Ethinyl Estradiol Tablets:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); breast pain, lump, or discharge; calf or leg pain, swelling, or tenderness; change in the amount of urine produced; chest pain or heaviness; confusion; coughing up blood; fainting; irregular heartbeat; left-sided jaw, neck, shoulder, or arm pain; mental or mood changes (eg, depression); migraines; missed menstrual period; numbness of an arm or leg; one-sided weakness; persistent, severe, or recurring headache or dizziness; persistent vaginal spotting; severe or persistent trouble sleeping; severe stomach pain or tenderness; shortness of breath; slurred speech; sudden, severe vomiting; swelling of the fingers, hands, legs, or ankles; symptoms of liver problems (eg, yellowing of the skin or eyes, fever, dark urine, pale stools, loss of appetite); unusual or severe vaginal bleeding; unusual tiredness or weakness; vaginal irritation or discharge; vision changes (eg, sudden vision loss, double vision).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

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Side Effects by Body System - for Healthcare Professionals

Genitourinary

Genitourinary side effects have included breakthrough bleeding, spotting, change in menstrual flow, amenorrhea, changes in cervical erosion and secretion, and breast tenderness. Changes in the cervical squamocolumnar junction and cervical secretions have also been reported.

Endocrine

Endocrine side effects have included increases in PBI, BEI levels, and a decrease in T3 uptake.

Hematologic

Hematologic side effects have included an increase in prothrombin time and clotting factors VII, VIII, IX, and X.

Hepatic

Hepatic side effects have included hepatic adenomas and cholestatic jaundice.

Dermatologic

Dermatologic side effects have included acne, melasma, chloasma, and pruritus.

General

General side effects have included weight gain/loss and hirsutism.

Psychiatric

The psychiatric side effects have included mental depression.

Cardiovascular

Cardiovascular side effects have included edema

Gastrointestinal

Gastrointestinal side effects have included nausea.

Nervous system

Nervous system side effects have included insomnia, headache and dizziness.

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