Norethindrone Side Effects
It is possible that some side effects of norethindrone may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
For the Consumer
Applies to norethindrone: oral tablets
Side effects include:
Menstrual abnormalities (amenorrhea; frequent, irregular, prolonged, or infrequent bleeding), nausea, weight changes, breast changes (tenderness, enlargement, secretion), headache.
For Healthcare Professionals
Applies to norethindrone: compounding powder, oral tablet
Genitourinary side effects have included breakthrough bleeding, spotting, change in menstrual flow, amenorrhea, changes in cervical erosion and secretion, and breast tenderness. Changes in the cervical squamocolumnar junction and cervical secretions have also been reported.
Endocrine side effects have included increases in PBI, BEI levels, and a decrease in T3 uptake.
Hematologic side effects have included an increase in prothrombin time and clotting factors VII, VIII, IX, and X.
Hepatic side effects have included hepatic adenomas and cholestatic jaundice.
Dermatologic side effects have included acne, melasma, chloasma, and pruritus.
General side effects have included weight gain/loss and hirsutism.
The psychiatric side effects have included mental depression.
Cardiovascular side effects have included edema
Gastrointestinal side effects have included nausea.
Nervous system side effects have included insomnia, headache and dizziness.
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