Neptazane Side Effects

Generic name: methazolamide

Note: This document contains side effect information about methazolamide. Some of the dosage forms listed on this page may not apply to the brand name Neptazane.

Some side effects of Neptazane may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to methazolamide: oral tablet

If you experience any of the following serious side effects, stop taking methazolamide (the active ingredient contained in Neptazane) and seek emergency medical attention or contact your doctor immediately:

• an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

• a sore throat or a fever;

• unusual bleeding or bruising;

• side or groin pain;

• tingling or tremors in the hands or feet; or

• a rash.

Other, less serious side effects may be more likely to occur. Continue to take methazolamide and talk to your doctor if you experience

• decreased appetite, nausea, vomiting, constipation, diarrhea, or changes in taste;

• drowsiness, dizziness, fatigue, or weakness;

• nervousness or tremor;

• headache or confusion;

• increased sensitivity of the skin to sunlight;

• worsening gout;

• loss of blood sugar control (if you are diabetic);

• ringing in your ears or hearing problems; or

• changes in vision.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

For Healthcare Professionals

Applies to methazolamide: compounding powder, oral tablet

Nervous system

Nervous system side effects have included paresthesias (most often a tingling in the extremities), hearing dysfunction, tinnitus, taste alteration, drowsiness, and confusion. Flaccid paralysis and convulsions have also been reported.

Gastrointestinal

Gastrointestinal side effects have included loss of appetite, nausea, vomiting, and diarrhea.

Genitourinary

Genitourinary side effects have included polyuria, hematuria, and glycosuria. Crystalluria and renal calculi have been reported rarely.

Hypersensitivity

Hypersensitivity reactions have included rare reports of toxic epidermal necrolysis, Stevens-Johnson syndrome, fulminant hepatic necrosis, agranulocytosis, aplastic anemia, and other blood dyscrasias. Photosensitivity has been reported occasionally.

Dermatologic

Dermatologic side effects have included urticaria.

Metabolic

Metabolic side effects have included metabolic acidosis and electrolyte disturbances.

General

General side effects have included fatigue and malaise.

Ocular

Ocular side effects have included transient myopia. This can usually be resolved with a reduction in dose or discontinuation of therapy.

Hepatic

Hepatic side effects have included hepatic insufficiency.

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