Methazolamide Dosage
This dosage information may not include all the information needed to use Methazolamide safely and effectively. See additional information for Methazolamide.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Glaucoma
Open-angle glaucoma: 50 to 100 mg orally 2 to 3 times daily
Secondary glaucoma: 50 to 100 mg orally 2 to 3 times daily
Acute angle-closure glaucoma (preoperatively only): 50 to 100 mg 2 to 3 times daily
Renal Dose Adjustments
CrCl less than 25 mL/min: not recommended
Liver Dose Adjustments
Not recommended for patients with severe liver disease. Patients with mild liver disease should be monitored carefully.
Precautions
Long-term methazolamide administration is contraindicated in patients with angle-closure glaucoma because it may permit closure of the angle to occur while the worsening of glaucoma is masked by decreased intraocular pressures.
A baseline CBC and platelet count should be obtained on all patients prior to initiating therapy and periodically throughout treatment to monitor for hematologic reactions common to all sulfonamides. Monitoring of serum electrolytes is also recommended.
Safety and efficacy in pediatric patients have not been established.
Dialysis
Data not available

