Monoferric Side Effects

Generic name: ferric derisomaltose

Medically reviewed by Drugs.com. Last updated on Sep 30, 2023.

Note: This document contains side effect information about ferric derisomaltose. Some dosage forms listed on this page may not apply to the brand name Monoferric.

Applies to ferric derisomaltose: intravenous solution.

Serious side effects of Monoferric

Along with its needed effects, ferric derisomaltose (the active ingredient contained in Monoferric) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking ferric derisomaltose:

Rare

• Blurred vision
• confusion
• cough
• difficulty swallowing
• dizziness
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• fast heartbeat
• hives, itching, rash
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• sweating
• tightness in the chest
• troubled breathing
• unusual tiredness or weakness

Incidence not known

• Chest pain
• fast, pounding, or irregular heartbeat or pulse
• fever or chills
• headache
• loss of consciousness
• nervousness
• pounding in the ears
• seizures
• slow heartbeat

Other side effects of Monoferric

Some side effects of ferric derisomaltose may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Nausea
• rash

Incidence not known

• Abdominal or stomach pain
• anxiety
• back pain
• bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
• burning, crawling, itching, numbness, prickling, "pins and needles" , or tingling feelings
• change or loss of taste
• constipation
• diarrhea
• joint or muscle pain
• muscle spasms
• vomiting

For Healthcare Professionals

Applies to ferric derisomaltose: intravenous solution.

Metabolic

Common (1% to 10%): Hypophosphatemia (serum phosphate under 2 mg/dL)

Frequency not reported: Iron overload^[Ref]

Hypersensitivity

Uncommon (0.1% to 1%): Serious or severe hypersensitivity

Postmarketing reports: Anaphylactic/anaphylactoid reaction, hypersensitivity^[Ref]

Dermatologic

Common (1% to 10%): Rash

Postmarketing reports: Erythema, urticaria, discoloration skin, pruritus, sweating^[Ref]

Gastrointestinal

Common (1% to 10%): Nausea

Postmarketing reports: Abdominal pain, nausea and vomiting, constipation, diarrhea^[Ref]

Cardiovascular

Postmarketing reports: Tachycardia, hypertension, hypotension, flushing, phlebitis^[Ref]

Local

Postmarketing reports: Extravasation, injection site reactions, long lasting brown discoloration at injection site^[Ref]

Musculoskeletal

Postmarketing reports: Back pain, muscle spasms, arthralgia, myalgia^[Ref]

Nervous system

Postmarketing reports: Dizziness, headache, paresthesia, dysgeusia, seizure, loss of consciousness, syncope^[Ref]

Other

Postmarketing reports: Fatigue, pyrexia, chest pain, chills, Fishbane reactions, influenza like symptoms^[Ref]

Hepatic

Postmarketing reports: Hepatic enzymes increased^[Ref]

Respiratory

Postmarketing reports: Dyspnea, cough^[Ref]

Psychiatric

Postmarketing reports: Anxiety^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer