Mecasermin Side Effects

It is possible that some side effects of mecasermin may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to mecasermin: subcutaneous solution

As well as its needed effects, mecasermin may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking mecasermin, check with your doctor immediately:

More common
  • Anxiety
  • bluish skin color of the fingertips
  • blurred vision
  • breathlessness
  • chest pain
  • chills
  • cold sweats
  • coma
  • confusion
  • cool, pale skin
  • depression
  • dizziness
  • fast heartbeat
  • headache
  • increased hunger
  • loss of hearing
  • nausea
  • nervousness
  • nightmares
  • rapid growth of normal cells of the thymus (no symptoms)
  • seizures
  • shakiness
  • slurred speech
  • thickening of the skin
  • unusual tiredness or weakness
Incidence not known
  • Change in the ability to see colors, especially blue or yellow
  • cough
  • difficult or labored breathing
  • difficulty with swallowing
  • hives or welts
  • itching
  • itching or hives at the injection site
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • limp
  • pain in the hip or knee
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the skin
  • shortness of breath
  • skin rash
  • tightness in the chest
  • vomiting
  • wheezing

Get emergency help immediately if any of the following symptoms of overdose occur while taking mecasermin:

Symptoms of overdose
  • Anxiety
  • arm or leg pain
  • backache
  • changes in vision
  • excessive sweating
  • extreme weakness
  • frequent urination
  • increase in hands and feet size
  • increased thirst
  • increased volume of pale, diluted urine
  • joint pain
  • stop in menstruation

Some mecasermin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common
  • Abnormal response of the tympanic membrane to air pressure
  • difficulty with moving
  • difficulty with swallowing
  • ear pain
  • earache
  • large, flat, blue or purplish patches in the skin
  • muffled hearing
  • muscle pain or stiffness
  • redness or swelling in the ear
  • sense of fullness in the ear
  • snoring
  • sore throat
  • voice changing

For Healthcare Professionals

Applies to mecasermin: subcutaneous solution

Local

Local side effects have included lipohypertrophy and bruising.

Cardiovascular

Cardiovascular side effects have included cardiac murmur.

Gastrointestinal

Gastrointestinal side effects have included vomiting.

Hematologic

Hematologic side effects have included thymus hypertrophy.

Musculoskeletal

Musculoskeletal side effects have included arthralgia and pain in extremities. Slipped capital femoral epiphysis and progression of scoliosis has been reported.

Respiratory

Respiratory side effects have included snoring and tonsillar hypertrophy.

Metabolic

Metabolic side effects have included hypoglycemia.

Other

Other side effects have included otitis media, serous otitis media, hypoacusis, fluid in middle ear, ear pain and abnormal tympanometry.

Nervous system

Nervous system side effects have included headache, dizziness, and convulsions. Intracranial hypertension has been reported.

Hypersensitivity

Hypersensitivity side effects have included anaphylaxis, generalized urticaria, angioedema, and dyspnea.

Dermatologic

Dermatologic side effects have included postmarketing reports of alopecia and abnormal hair texture.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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