Lindane topical Side Effects

Not all side effects for lindane topical may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to lindane topical: topical cream, topical lotion, topical shampoo

In addition to its needed effects, some unwanted effects may be caused by lindane topical. In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking lindane topical, check with your doctor or nurse as soon as possible:

  • Convulsions (seizures)
  • dizziness, clumsiness, or unsteadiness
  • fast heartbeat
  • muscle cramps
  • nervousness, restlessness, or irritability
  • vomiting
  • skin irritation not present before use of lindane
  • skin rash

After you stop taking this drug, it is possible that you may still experience side effects that need medical attention. If you notice any of the following side effects check with your doctor immediately:

Serious side effects have resulted in patients using lindane. Sometime it has occurred even when used according to the labeled directions. Serious side effects have been reported following lindane use with repeat or prolonged use, but also in rare cases following a single application. You should discuss these possible effects with your doctor.

For Healthcare Professionals

Applies to lindane topical: topical liquid, topical lotion, topical shampoo

Nervous system

Seizures reported with topical lindane use for scabies have generally followed its inappropriate use. Such uses include application of the lotion after a bath to hydrated skin, repeated applications, or prolonged use. Many of the patients who have experienced seizures following lindane use are infants and small children.

Pseudotumor cerebri has been reported following long-term exposure to a lindane veterinary product.

Nervous system side effects have included dizziness, paresthesias, headache, disorientation, seizures, and death. Seizures have occurred after both improper and proper use.


Many reports of aplastic anemia occurred in the 1950s and 60s during which time lindane vaporizers were used in the home. These devices heated lindane pellets and continuously released a vapor into the air.

Hematologic abnormalities, including aplastic anemia, have been reported anecdotally in patients who were exposed to lindane pesticide or veterinarian products. At least two patients have experienced aplastic anemia following repeated, long-term use (over three to six weeks) of topical lindane for the treatment of scabies.


Dermatologic side effects have included alopecia, dermatitis, contact dermatitis, pruritus, and urticaria.

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