Interferon alfa-n3 Side Effects

Please note - some side effects for Interferon alfa-n3 may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects of Interferon alfa-n3 - for the Consumer

Interferon Alfa-n3 Solution

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Interferon Alfa-n3 Solution:

Appetite loss; changes in taste or hearing; chills; diarrhea; fatigue; flu-like symptoms; headache; muscle and joint pain; nausea; pain or other reaction at the site of injection; stomach pain; vomiting.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; bloody diarrhea; chest pain; dark urine or changes in amount of urine; depression; difficulty sleeping; dizziness; drowsiness; intolerance to heat or cold; irregular heartbeat; one-sided weakness (arm, leg); persistent sore throat; poor coordination; pounding in the chest; psychotic or manic behavior; seizures; severe stomach/abdominal pain; suicidal thoughts; tingling hands or feet; unusual bleeding/bruising; unusual increase in thirst; vision changes; vomiting blood; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Side Effects by Body System - for Healthcare Professionals

General

General flu-like side effects including fever (40%), headache (31%), chills (14%), fatigue (14%), malaise (9%), and increased sweating (2%) have been reported most frequently.

Musculoskeletal

Musculoskeletal side effects including myalgia (45%), arthralgia (5%), and back pain (4%) have been reported. Muscle cramps, tingling of legs and feet, and hot sensation on bottom of feet have rarely been reported.

Nervous system

Nervous system side effects including headache (31%), dizziness (9%), and insomnia (2%) have infrequently been reported.

Gastrointestinal

Gastrointestinal side effects including nausea (4%), vomiting (3%), dyspepsia/heartburn (3%), and diarrhea (2%) have been reported.

Dermatologic

Dermatologic side effects including generalized pruritus and rash on neck have rarely been reported.

Psychiatric

Psychiatric side effects including depression (2%) and nervousness (1%) have been reported.

Respiratory

Respiratory side effects including nose/sinus drainage (2%) have been reported the most frequently. Tongue hyperesthesia, strange taste in mouth, increased salivation, pharyngitis, nosebleed, and throat tightness have been reported in less than 1% of patients.

Local

Local side effects including itching and pain at the application site have rarely been reported.

Ocular

Ocular side effects including visual disturbance (1%) have been reported.

Genitourinary

Genitourinary side effects including herpes labialis and dysuria have been reported in 1% of patients.

Immunologic

Immunologic side effects including swollen lymph nodes (1%) have been reported.

Hematologic

Hematologic side effects including decreased white blood cells (11%) have been reported.

Other

Other side effects including left groin lymph node swelling, excessive thirst, heat intolerance, hot flashes, photosensitivity, and decrease in concentration have rarely been reported.

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