Hydroxyamphetamine / tropicamide ophthalmic Side Effects

Medically reviewed by Drugs.com. Last updated on Feb 23, 2024.

Applies to hydroxyamphetamine/tropicamide ophthalmic: ophthalmic solution.

Serious side effects

Along with its needed effects, hydroxyamphetamine/tropicamide ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking hydroxyamphetamine / tropicamide ophthalmic:

Rare

Blurred vision
chest pain or discomfort
confusion
dizziness
faintness or lightheadedness when getting up from a lying or sitting position
fast, slow, or irregular heartbeat
nausea
pain or discomfort in arms, jaw, back or neck
shortness of breath
sudden sweating
unusual tiredness or weakness

Frequency of side effects not known

Agitation
anxiety
cold, clammy, pale skin
cough
difficulty swallowing
eye pain
failure to recognize people
hives
irritability
itching
hyperactivity or restlessness
loss of consciousness
loss of vision
mood or mental changes
nervousness
nightmares
pounding heartbeat or pulse
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
seeing, hearing, or feeling things that are not there
skin rash
tightness in chest
tremor
unusual behavior such as disorientation to time or place
unusual feeling of excitement
wheezing

Symptoms of Overdose

Get emergency help immediately if any of the following symptoms of overdose occur while taking hydroxyamphetamine / tropicamide ophthalmic:

Bloating
blurred vision
chest pain or discomfort
diarrhea
dizziness
enlarged pupils
fainting
fast, slow, or irregular heartbeat
gas
headache
heartburn
indigestion
lightheadedness
loss of appetite
nausea
nervousness
pounding in the ears
pounding or rapid pulse
stomach pain
sweating
vomiting

Other side effects

Some side effects of hydroxyamphetamine / tropicamide ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Frequency of side effects not known

Change in color vision
difficulty seeing at night
dry mouth
headache
increased sensitivity of eyes to sunlight
muscle stiffness or tightness
temporary stinging in the eyes

For Healthcare Professionals

Applies to hydroxyamphetamine / tropicamide ophthalmic: ophthalmic solution.

General

Transient stinging, dry mouth, blurred vision, photophobia with or without corneal staining, tachycardia, headache, allergic reactions, nausea, vomiting, pallor, and muscle rigidity have been reported following use of tropicamide and/or hydroxyamphetamine hydrobromide and thus may occur with the combination product. Rare but serious cardiovascular events (including death due to myocardial infarction, ventricular fibrillation, and significant hypotensive episodes) have occurred shortly following instillation of this drug.^[Ref]

Ocular

Frequency not reported: Intraocular pressure increased, vision blurred, photophobia, corneal staining, transient stinging^[Ref]

Cardiovascular

Frequency not reported: Myocardial infarction, ventricular fibrillation, hypotension, tachycardia, vasomotor collapse, cardiorespiratory collapse^[Ref]