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Humate-P Side Effects

Generic Name: antihemophilic factor / von willebrand factor

Note: This page contains information about the side effects of antihemophilic factor / von willebrand factor. Some of the dosage forms included on this document may not apply to the brand name Humate-P.

For the Consumer

Applies to antihemophilic factor / von willebrand factor: intravenous powder for solution

In addition to its needed effects, some unwanted effects may be caused by antihemophilic factor / von willebrand factor. In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking antihemophilic factor / von willebrand factor, check with your doctor or nurse immediately:

More common
  • Difficulty with breathing or swallowing
  • dizziness
  • fast heartbeat
  • fever
  • hives or welts
  • itching
  • nausea
  • reddening of the skin, especially around the ears
  • shortness of breath
  • skin rash
  • swelling of the face, throat, or tongue
  • unusual tiredness or weakness
Incidence not known
  • Cough
  • tightness in the chest
  • vomiting
  • wheezing

For Healthcare Professionals

Applies to antihemophilic factor / von willebrand factor: intravenous powder for injection


Hypersensitivity side effects have included allergic-anaphylactic reactions including urticaria, chest tightness, rash, pruritus, edema, and shock.[Ref]


Hematologic side effects have included postoperative wound or injection-site bleeding, including, epistaxis, cerebral hemorrhage, subdural hematoma, gastrointestinal bleeding, menorrhagia, hemoptysis, hematuria, groin bleed, ear bleed, shoulder bleed, anemia, and decreased hemoglobin.[Ref]


Cardiovascular side effects have included chest pain, thrombophlebitis, phlebitis, peripheral edema, and vasodilation.[Ref]


Gastrointestinal side effects have included nausea, constipation, vomiting, and sore throat.[Ref]

Nervous system

Nervous system side effects have included dizziness, headache, increased sweating, insomnia, paresthesia and extremity pain.[Ref]


Genitourinary side effects have included urinary retention and urinary tract infection.[Ref]


General side effects have included pain, fever, abdominal pain, infection, back pain, and facial edema.[Ref]


1. "Product Information. Humate-P (antihemophilic factor-von Willebrand factor)." CSL Behring, King of Prussia, PA.

Not all side effects for Humate-P may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

More about Humate-P (antihemophilic factor / von willebrand factor)

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