Haegarda Side Effects
Generic name: C1 esterase inhibitor (human)
Note: This document contains side effect information about C1 esterase inhibitor (human). Some dosage forms listed on this page may not apply to the brand name Haegarda.
Applies to C1 esterase inhibitor (human): powder for solution. Other dosage forms:
Serious side effects of Haegarda
Along with its needed effects, C1 esterase inhibitor (human) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking C1 esterase inhibitor (human):
More common
- Chest pain or tightness
- head congestion
- hoarseness or other voice changes
- nausea
- pain or tenderness around the eyes and cheekbones
- rash
- sore throat
- trouble breathing
- vomiting
Less common
- Bleeding gums
- collection of blood under the skin
- coughing up blood
- deep, dark purple bruise
- difficulty with swallowing
- dizziness
- hard lump
- headache
- increased menstrual flow or vaginal bleeding
- itching, pain, flushing, redness, or swelling of the skin
- nosebleeds
- paralysis
- prolonged bleeding from cuts
- red or black, tarry stools
- red or dark brown urine
- swelling
- unusually warm skin
Incidence not known
- Confusion
- difficulty with speaking
- dizziness
- double vision
- fast heartbeat
- general tiredness and weakness
- hives
- inability to move the arms, legs, or facial muscles
- numbness or tingling in the face, arms, or legs
- pain, redness, or swelling in the arm or leg
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- slow speech
- trouble speaking, thinking, or walking
Other side effects of Haegarda
Some side effects of C1 esterase inhibitor (human) may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Diarrhea
- headache
- pain
- stomach pain
Less common
- Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
- change in taste
- fever
- loss of taste
- muscle aches
- pain at the catheter site
- stuffy or runny nose
- unusual tiredness or weakness
For Healthcare Professionals
Applies to C1 esterase inhibitor (human): intravenous kit, intravenous powder for injection, subcutaneous powder for injection.
Respiratory
Respiratory side effects have included sinusitis, bronchitis, upper respiratory tract infection, and viral upper respiratory tract infection.[Ref]
Nervous system
Nervous system side effects have included headache.[Ref]
Musculoskeletal
Musculoskeletal side effects have included limb injury, back pain, and pain in extremity.[Ref]
Dermatologic
Dermatologic side effects have included pruritus.[Ref]
Cardiovascular
Cardiovascular side effects have included postmarketing reports of thrombotic events including deep vein thrombosis, myocardial infarction, and transient ischemic attack.[Ref]
Frequently asked questions
- What is Haegarda used for and how does it work?
- How is Berinert administered?
- What is Ruconest used for and how does it work?
- How does Berinert work for Hereditary Angioedema (HAE)?
- What is Cinryze used for and how does it work?
More about Haegarda (C1 esterase inhibitor (human))
- Check interactions
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- Reviews (1)
- Drug images
- Dosage information
- Patient tips
- During pregnancy
- FDA approval history
- Drug class: hereditary angioedema agents
- Breastfeeding
- En español
Patient resources
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Professional resources
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References
1. Product Information. Cinryze (C1 esterase inhibitor, human). ViroPharma Incorporated. 2022.
2. Gandhi PK, Gentry WM, Bottorff MB. Thrombotic events associated with C1 esterase inhibitor products in patients with hereditary angioedema: investigation from the United States Food and Drug Administration adverse event reporting system database. Pharmacotherapy. 2012;32:902-9.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.