Gadodiamide Side Effects
Not all side effects for gadodiamide may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to gadodiamide: intravenous solution
In addition to its needed effects, some unwanted effects may be caused by gadodiamide. In the event that any of these side effects do occur, they may require medical attention.
If any of the following side effects occur while taking gadodiamide, check with your doctor or nurse immediately:Less common or rare
- bloody, black, or tarry stools
- blurred vision
- burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- change in consciousness
- changes in skin color
- chest pain or discomfort
- clumsiness or unsteadiness
- decreased urine output
- difficult or labored breathing
- difficulty controlling your bladder or bowels
- difficulty swallowing
- difficulty walking
- dilated neck veins
- extreme fatigue
- fast, slow, or irregular heartbeat
- feeling faint, dizzy, or lightheaded
- feeling of warmth or heat
- feeling sad or depressed
- feeling unusually cold
- flushing or redness of the skin, especially on the face and neck
- general feeling of discomfort or illness
- headache, severe and throbbing
- irregular breathing
- loss of bladder control
- loss of consciousness
- muscle cramps
- muscle twitching
- numbness or tingling in your arms, legs, or face
- pain or discomfort in the arms, jaw, back, or neck
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- rapid weight gain
- redness of the face, neck, arms, and occasionally, upper chest
- shakiness and unsteady walk
- shakiness in the legs, arms, hands, or feet
- shortness of breath
- skin rash
- slurred speech or problems swallowing
- sudden sweating
- swelling of the face, fingers, feet, ankles, or lower legs
- tightness in the chest
- total body jerking
- trembling or shaking of the hands or feet
- troubled breathing
- unsteadiness, trembling, or other problems with muscle control or coordination
- unusual tiredness or weakness
- weight gain
- Burning or itching of the skin
- joint stiffness
- limited range of motion in the arms and legs
- muscle weakness
- pain that is deep in the hip bone or ribs
- partial or slight paralysis
- red or dark patches on the skin
- skin swelling, hardening, or tightening
Some of the side effects that can occur with gadodiamide may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:Less common or rare
- Abdominal or stomach pain
- bad, unusual, or unpleasant (after) taste
- bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
- bloated or full feeling
- change in taste
- changes in vision
- continuing ringing or buzzing or other unexplained noise in the ears
- difficulty with moving
- dry mouth
- excess air or gas in the stomach
- hearing loss
- hives or welts
- increased sweating
- joint pain
- muscle pains or stiffness
- redness of the skin
- runny nose
- stuffy nose
- swollen joints
For Healthcare Professionals
Applies to gadodiamide: injectable solution
Cardiovascular side effects have included cardiac failure, arrhythmia and myocardial infarction. Also reported include vasodilation, flushing, chest pain, deep thrombophlebitis, and rarely, arrhythmia and myocardial infarction resulting in death in patients with ischemic heart disease.
Nervous system side effects have included headache, tinnitus, taste loss, taste perversion, and dizziness. Convulsions including grand mal, ataxia, abnormal coordination, paresthesia, tremor, aggravated multiple sclerosis (characterized by sensory and motor disturbances), and aggravated migraine have been reported.
Gastrointestinal side effects have included nausea, abdominal pain, diarrhea, eructation, dry mouth, vomiting, and melena.
Hypersensitivity side effects have included anaphylactoid reactions (characterized by cardiovascular, respiratory, and cutaneous symptoms).
General side effects have included fever, hot flushes, rigors, fatigue, malaise, pain, and syncope.
Hepatic side effects have included abnormal hepatic function.
Respiratory side effects have included rhinitis and dyspnea.
Ocular side effects have included abnormal vision.
Renal side effects have included acute reversible renal failure.
Musculoskeletal side effects have included arthralgia and myalgia.
Dermatologic side effects have included pruritus, rash, erythematous rash, increased sweating, and urticaria.
More about gadodiamide
- Other brands: Omniscan
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