Gadodiamide use while Breastfeeding

Drugs containing Gadodiamide: Omniscan

Gadodiamide Levels and Effects while Breastfeeding

Summary of Use during Lactation

There is no published experience with gadodiamide during breastfeeding. Guidelines developed by several professional organizations state that breastfeeding need not be disrupted after a nursing mother receives a gadolinium-containing contrast medium.[1][2][3] However, gadodiamide releases more free gadolinium than most other gadolinium-containing contrast agents and European sources recommend that the mother pump and discard milk for 24 hours after receiving gadodiamide.[4][5] Other agents may be preferred, especially while nursing a newborn or preterm infant.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Gadopentetate

References

1. American College of Radiology Committee on Drugs and Contrast Media. Administration of contrast media to breast-feeding mothers. In, ACR manual on contrast media. 2012;Version 8:79-80.

2. Chen MM, Coakley FV, Kaimal A, Laros RK Jr. Guidelines for computed tomography and magnetic resonance imaging use during pregnancy and lactation. Obstet Gynecol. 2008;112:333-40. PMID: 18669732

3. Patenaude Y, Pugash D, Lim K et al. The use of magnetic resonance imaging in the obstetric patient. J Obstet Gynaecol Can. 2014;36:349-55. PMID: 24798674

4. Webb JA, Thomsen HS. Gadolinium contrast media during pregnancy and lactation. Acta Radiol. 2013;54:599-600. PMID: 23966544

5. European Society of Urogenital Radiology. ESUR guidelines on contrast media. 2012;Version 8.0. http://www.esur.org/guidelines

Gadodiamide Identification

Substance Name

Gadodiamide

CAS Registry Number

122795-43-1

Drug Class

Contrast Media

Diagnostic Agents

Administrative Information

LactMed Record Number

532

Last Revision Date

20140708

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

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