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Fluoxymesterone Side Effects

Not all side effects for fluoxymesterone may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to fluoxymesterone: oral tablets

Side effects include:

Males: Gynecomastia, frequent or persistent penile erections.

Females: Amenorrhea, other menstrual irregularities, inhibition of gonadotropin secretion, virilization (e.g., deepening of the voice, clitoral enlargement).

For Healthcare Professionals

Applies to fluoxymesterone: compounding powder, oral tablet


Rare (less than 0.1%): Hepatocellular neoplasms, peliosis hepatis, hepatic coma
Frequency not reported: Cholestatic jaundice, alterations in liver function tests[Ref]


Frequency not reported: Females: Virilization, gonadotropin secretion inhibition, amenorrhea and other menstrual irregularities; Males: Gynecomastia, oligospermia, penile erections of excessive frequency and duration[Ref]


Frequency not reported: Increased serum cholesterol; retention of sodium, chloride, water, potassium, calcium, and inorganic phosphates[Ref]


Frequency not reported: Polycythemia; suppression of clotting factors II, V, VII, and X; bleeding in patients on concomitant anticoagulant therapy[Ref]


Frequency not reported: Hirsutism, male pattern baldness, acne[Ref]


Frequency not reported: Nausea[Ref]

Nervous system

Frequency not reported: Headache, generalized paresthesia[Ref]


Rare (less than 0.1%): Anaphylactoid reactions
Frequency not reported: Hypersensitivity reactions[Ref]


Frequency not reported: Increased or decreased libido, anxiety, depression[Ref]


1. "Product Information. Androxy (fluoxymesterone)." Upsher-Smith Laboratories Inc, Minneapolis, MN.

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