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Flonase Side Effects

Generic Name: fluticasone nasal

Note: This page contains information about the side effects of fluticasone nasal. Some of the dosage forms included on this document may not apply to the brand name Flonase.

For the Consumer

Applies to fluticasone nasal: nasal spray

In addition to its needed effects, some unwanted effects may be caused by fluticasone nasal (the active ingredient contained in Flonase). In the event that any of these side effects do occur, they may require medical attention.

Severity: Major

You should check with your doctor immediately if any of these side effects occur when taking fluticasone nasal:

More common:
  • Bloody nose
Less common:
  • Cough
  • fever
  • headache
  • muscle aches
  • sore throat
  • sores inside the nose
  • stuffy or runny nose
  • unusual tiredness or weakness
Incidence not known:
  • Difficulty with swallowing
  • dizziness
  • fast heartbeat
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the skin
  • skin rash, itching, hives or welts
  • tightness in the chest

Severity: Minor

Some of the side effects that can occur with fluticasone nasal may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:
  • Back pain

For Healthcare Professionals

Applies to fluticasone nasal: nasal spray

Endocrine

Frequency not reported: Hypothalamic-pituitary-adrenal (HPA) axis effects (including growth reduction)[Ref]

Nervous system

Common (1% to 10%): Headache, unpleasant taste, unpleasant smell[Ref]

Gastrointestinal

Common (1% to 10%): Toothache, nausea, diarrhea, abdominal distension, vomiting, gastrointestinal gaseous symptoms
Frequency not reported: Gum signs and symptoms[Ref]

Hypersensitivity

Very rare (less than 0.01%): Hypersensitivity reactions (including anaphylaxis, angioedema, rash, urticaria, bronchospasm)[Ref]

Ocular

Common (1% to 10%): Conjunctivitis
Very rare (less than 0.01%): Cataracts, glaucoma, raised intraocular pressure
Frequency not reported: Transient ocular changes[Ref]

Immunologic

Frequency not reported: Candida albicans infection, immunosuppression[Ref]

Respiratory

Very common (10% or more): Nasopharyngitis (26%), epistaxis (20%)
Common (1% to 10%): Pharyngolaryngeal pain, nasal ulceration, cough, pharyngitis, bronchitis, nasal dryness, throat irritation, throat dryness, blood in nasal mucosa, nasal irritation
Uncommon (0.1% to 1%): Rhinalgia, nasal discomfort (including nasal burning, nasal soreness)
Postmarketing reports: Nasal septal perforation[Ref]

General

The most commonly reported side effects were nasopharyngitis, epistaxis, and pyrexia.[Ref]

Musculoskeletal

Common (1% to 10%): Back pain[Ref]

Other

Very common (10% or more): Pyrexia
Frequency not reported: Impaired wound healing[Ref]

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. "Product Information. Flonase (fluticasone)." Glaxo Wellcome, Research Triangle Park, NC.

Not all side effects for Flonase may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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