Extendryl PSE Side Effects
Generic Name: methscopolamine / pseudoephedrine
Note: This page contains information about the side effects of methscopolamine / pseudoephedrine. Some of the dosage forms included on this document may not apply to the brand name Extendryl PSE.
Not all side effects for Extendryl PSE may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to methscopolamine / pseudoephedrine: extended-release tablets
Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur while taking methscopolamine / pseudoephedrine:
Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; loss of appetite; nausea; nervousness or anxiety; restlessness; trouble sleeping; upset stomach; vomiting; weakness.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; mental or mood changes; seizures; severe dizziness, lightheadedness, or headache; tremor; vision changes.
For Healthcare Professionals
Applies to methscopolamine / pseudoephedrine: oral tablet extended release
Cardiovascular side effects have included cardiac palpitations. In general, sympathomimetics have been associated with tachycardia, arrhythmias, and cardiovascular collapse with hypotension.[Ref]
Nervous system side effects have included drowsiness, lassitude, increased irritability and excitement (especially in children). Other side effects associated with sympathomimetic amines have included headache, dizziness, anxiety, fear, nervousness, restlessness, tremor, weakness, insomnia, hallucinations, convulsions, and CNS depression.
Antihistamines and anticholinergic drugs side effects have included drowsiness and dizziness.[Ref]
Gastrointestinal side effects have included nausea and excessive dryness of the mouth, nose and throat.[Ref]
Ocular side effects have included blurred vision.[Ref]
Genitourinary side effects associated with the used of sympathomimetic amines have included dysuria and urinary retention in patients with prostatic hypertrophy.[Ref]
Respiratory side effects associated with the use of sympathomimetics have included respiratory difficulty.[Ref]
1. "Product Information. PSE 120/MSC 2.5 (methscopolamine-pseudoephedrine)." Cypress Pharmaceutical Inc, Madison, MS.
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